Effect of temporal location of correction of monochromatic aberrations on the dynamic accommodation response.

Dynamic correction of monochromatic aberrations of the eye is known to affect the accommodation response to a step change in stimulus vergence. We used an adaptive optics system to determine how the temporal location of the correction affects the response. The system consists of a Shack-Hartmann sensor sampling at 20 Hz and a 37-actuator piezoelectric deformable mirror. An extra sensing channel allows for an independent measure of the accommodation level of the eye. The accommodation response of four subjects was measured during a +/- 0.5 D step change in stimulus vergence whilst aberrations were corrected at various time locations. We found that continued correction of aberrations after the step change decreased the gain for disaccommodation, but increased the gain for accommodation. These results could be explained based on the initial lag of accommodation to the stimulus and changes in the level of aberrations before and after the stimulus step change. Future considerations for investigations of the effect of monochromatic aberrations on the dynamic accommodation response are discussed.

Effect of correction of ocular aberration dynamics on the accommodation response to a sinusoidally moving stimulus.

We used an adaptive optics system to correct the aberration dynamics of five subjects while they fixated on a monochromatic stimulus undergoing sinusoidal vergence changes between 1.5 and 2.5 D, at a temporal frequency of 0.2 Hz. The aberrations were measured at 20 Hz using a Shack-Hartmann sensor and corrected using a 37-actuator deformable mirror. The accommodation response (AR) was analyzed in terms of the gain and phase lag. Manipulation of aberrations significantly affected the gain of the AR for only one subject when the odd-order aberrations were corrected. The predictability of the sinusoidal stimulus could account for the lack of an effect in the remaining subjects and conditions.

Dual wavefront sensing channel monocular adaptive optics system for accommodation studies.

Manipulation of the eye's aberrations using adaptive optics (AO) has shown that optical imperfections can affect the dynamic accommodation response. A limitation of current system designs used for such studies is an inability to make direct measurements of the eye's aberrations during the experiment. We present an AO system which has a dual wavefront sensing channel. The corrective device is a 37-actuator piezoelectric deformable mirror. The measurements used to control the mirror, and direct measurements of the eye's aberrations, are captured on a single Shack-Hartmann sensor. Other features of the system include stroke amplification of the deformable mirror and a rotating diffuser to reduce speckle.We demonstrate the utility of the system by investigating the impact of aberration dynamics on the control of steady-state accommodation on four subjects.

Role of ocular aberrations in dynamic accommodation control.

BACKGROUND: Accommodation control is mediated by a number of cues, including blur,chromatic aberration and target proximity. Data from wavefront measurements have shown clear shifts in ocular aberrations during increasing accommodative demand, most notably a negative shift in spherical aberration. Work in adaptive optics, where aberrations have been corrected, has suggested a role for aberrations in the control of accommodation for some individuals. This study aimed to determine the relative effects of aberration correction and inversion on closed-loop stepwise accommodation responses to small increases and decreases in stimulus vergence. METHODS: An adaptive optics system was used to modify ocular aberrations, while five participants viewed a high contrast target stepping 0.5 D in an inward or outward direction. Aberrations were variously unchanged, corrected or inverted following the step change in stimulus vergence. A Shack-Hartmann wavefront sensor was used to record accommodative responses to the stepwise changes in stimulus vergence. Accommodative response data were analysed using a curve fitting method to calculate the gain,latency and response time. RESULTS: Correction of aberrations failed to have a significant effect on dynamic accommodative responses. Inversion of even-order aberration terms produced a significant reduction in accommodative response gain for outward steps in stimulus vergence.Additionally, an increase in the number of accommodative responses in the wrong direction was seen following aberration inversion. Inward steps were not altered significantly by aberration inversion. CONCLUSION: Accommodation in humans appears to derive a cue from the even-order aberrations of the eye to help guide the initial direction of responses to reductions in stimulus vergence (that is, disaccommodation). With all aberrations and even-order aberrations inverted, the number of incorrect directional responses to outward moving stimuli increases, suggesting that aberrations are important in determining the initial path of stepwise accommodative responses.