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1.
J Child Orthop ; 5(3): 225-30, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21779309

ABSTRACT

BACKGROUND: Lengthening of soft-tissue contractures is frequently required in children with a wide variety of congenital and acquired deformities. However, little is known about the biomechanics of surgical procedures which are commonly used in contracture surgery, or if variations in technique may have a bearing on surgical outcomes. We investigated the hypothesis that the site of intramuscular tenotomy (IMT) within the muscle-tendon-unit (MTU) of the tibialis posterior (TP) would affect the lengthening characteristics. METHODS: We performed a randomized trial on paired cadaver tibialis posterior muscle-tendon-units (TP-MTUs). By random allocation, one of each pair of formalin-preserved TP-MTUs received a high IMT, and the other a low IMT. These were individually tensile-tested with an Instron(®) machine under controlled conditions. A graph of load (Newtons) versus displacement (millimetres) was generated for each pair of tests. The differences in lengthening and load at failure for each pair of TP-MTUs were noted and compared using paired t tests. RESULTS: We found 48% greater lengthening for low IMT compared to high IMT for a given load (P = 0.004, two tailed t test). Load at failure was also significantly lower for the low IMT. These findings confirm our hypothesis that the site of the tenotomy affects the amount of lengthening achieved. This may contribute to the reported variability in clinical outcome. CONCLUSIONS: Understanding the relationship between tenotomy site and lengthening may allow surgeons to vary the site of the tenotomy in order to achieve pre-determined surgical goals. It may be possible to control the surgical "dose" by altering the position of the intramuscular tenotomy within the muscle-tendon-unit.

2.
J Pediatr Orthop B ; 14(6): 389-404, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16200013

ABSTRACT

The management of the upper limb in cerebral palsy is often complex and challenging. Effective treatment requires a multidisciplinary approach involving paediatricians, occupational therapists, physiotherapists, orthotists and upper extremity surgeons. Interventions are generally aimed at improving function and cosmesis by spasticity management, preventing contractures and correcting established deformities. Treatment objectives vary according to each child and range from static correction of deformities to ease nursing care, to improvements in dynamic muscle balance to augment hand function. Botulinum toxin A therapy has been shown to relieve spasticity and improve function in the short term. Surgery is also effective but requires careful patient selection, as many children with cerebral palsy are not candidates for surgery. Occupational therapy and physiotherapy have small treatment effects alone but are essential adjuncts to medical and surgical management.


Subject(s)
Cerebral Palsy/therapy , Muscle Spasticity/therapy , Upper Extremity , Botulinum Toxins, Type A/therapeutic use , Cerebral Palsy/complications , Cerebral Palsy/physiopathology , Humans , Muscle Spasticity/etiology , Muscle Spasticity/physiopathology , Neuromuscular Agents/therapeutic use , Upper Extremity/physiopathology , Upper Extremity/surgery
3.
Injury ; 36(12): 1467-75, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16243333

ABSTRACT

OBJECTIVE: To review the functional outcome of patients with complex tibial plateau fractures treated with fine-wire fixation. DESIGN: Retrospective review with follow-up of patients in outpatient clinic. SETTING: Tertiary trauma center. PATIENTS: All patients who had fine-wire fixation for tibial plateau fractures between 1996 and January 2001 were reviewed. INTERVENTIONS: Fine-wire fixation with/without limited internal fixation for complex tibial plateau fractures. MAIN OUTCOME MEASURES: Knee range of motion, adequacy of articular surface reduction, mechanical axis, Knee Society Clinical Rating Scale and Short-Form 36 Health Questionnaire. RESULTS: Eighteen of twenty-one eligible patients were available for follow-up. There were 14 Shatzker VI and 4 V fractures. Seven fractures were open. Average follow-up was 28.2 months. All fractures united. There were three cases of delayed union, all progressed to union following additional procedures and bone grafting. There were no cases of osteomyelitis, septic arthritis or deep vein thrombosis. Seven patients had Knee Society Clinical Rating Scores of good/excellent (38.9%), and 11 had fair/poor scores (61.1%). Abnormal mechanical axes and multiple co-morbid injuries were associated with poorer outcomes. Although SF-36 scores were lower in the study group compared to matched population norms, 15 of 18 patients had full or partial return to pre-injury levels of functioning. CONCLUSION: Fine-wire fixation with limited internal fixation is a satisfactory method of managing complex high-energy fractures of the tibial plateau where soft tissue injury and bony comminution make traditional techniques of open reduction and internal fixation unsuitable.


Subject(s)
Fracture Fixation/methods , Fracture Healing , Fractures, Closed/rehabilitation , Fractures, Open/rehabilitation , Tibial Fractures/rehabilitation , Adult , Aged , Bone Wires , Female , Follow-Up Studies , Fracture Fixation/instrumentation , Fractures, Closed/surgery , Fractures, Open/surgery , Humans , Male , Middle Aged , Retrospective Studies , Statistics, Nonparametric , Surgical Wound Infection , Tibial Fractures/surgery
4.
J Pediatr Orthop ; 25(3): 286-91, 2005.
Article in English | MEDLINE | ID: mdl-15832139

ABSTRACT

Most clinicians who perform botulinum toxin A injections for children with cerebral palsy do so using the "free-hand" or manual technique without using radiologic or electrophysiologic guidance to aid needle placement. The objective of this study was to investigate the accuracy of manual needle placement compared with needle placement guided by electrical stimulation. A total of 1,372 separate injections for upper and lower limb spasticity were evaluated in 226 children with cerebral palsy. The accuracy of manual needle placement compared with electrical stimulation was acceptable only for gastroc-soleus (>75%); it was unacceptable for the hip adductors (67%), medial hamstrings (46%), tibialis posterior (11%), biceps brachii (62%), and forearm and hand muscles (13% to 35%). The authors recommend using electrical stimulation or other guidance techniques to aid accurate needle placement in all muscles except the gastroc-soleus. Further study is needed to determine whether more accurate injecting will lead to better functional outcomes and more efficient use of botulinum toxin A.


Subject(s)
Botulinum Toxins, Type A/administration & dosage , Cerebral Palsy/diagnosis , Neuromuscular Agents/administration & dosage , Paralysis/drug therapy , Adolescent , Child , Child, Preschool , Electric Stimulation , Female , Humans , Infant , Injections, Intramuscular , Male , Paralysis/etiology
5.
Hand Clin ; 19(4): 591-600, 2003 Nov.
Article in English | MEDLINE | ID: mdl-14596551

ABSTRACT

Clinical experience thus far has shown BoNT-A to be a safe and efficacious method in the short to medium term management of spasticity of the upper limb in cerebral palsy. The relaxation of hypertonic musculature allows for improvement in function and posture, reduction of pain, and in some patients, improvement in cosmesis. It is also a valuable tool in predicting response to and guiding contemplated muscle-tendon surgery. Careful patient selection, detailed clinical assessment of deformity and disability, and a clear outline of treatment goals are essential to good outcomes. Further work needs to be done to determine optimum doses of BoNT-A for individual muscles and to evaluate the long-term outcome of repeated injections.


Subject(s)
Arm/physiopathology , Botulinum Toxins, Type A/therapeutic use , Cerebral Palsy/drug therapy , Neuromuscular Agents/therapeutic use , Cerebral Palsy/physiopathology , Dose-Response Relationship, Drug , Humans , Injections, Intramuscular
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