[Estimation of the renin-angiotensin-aldosterone system, water and electrolyte imbalance and endothelial function in newborns of women with chronic hypertension].

The aim of this study was to evaluate the parameters of renin-angiotensin-aldosterone system, natriuretic peptides, and markers of endothelial function in the early neonatal period and at the age of 3 months in 83 full-term infants of women with chronic hypertension, there were: 60 newborns from women with chronic hypertension of mild to moderate severity (main group) and 23 newborns from women without hypertension (comparison group). The levels of the renin angiotensin-II, aldosterone, natriuretic peptides, endothelin-1, in cord and peripheral blood were determined by immunoassay, the metabolites of stable oxide nitric--by Griess method. The newborn of women with chronic hypertension showed a significant elevation of renin, angiotensin II and brain natriuretic peptide at birth. A statistically significant increase in concentration of atrial natriuretic peptide (aANP1-28) was determined to the 3-5 days of life. Significantly high levels of renin, angiotensin II, endothelin-1 and decreased levels of endogenous nitrite at the age of 3 months of life was found. The results findings suggest that prenatal activation of the renin-angiotensin-aldosterone system of the fetus, continuing to be in the newborn of women with chronic hypertension during the first three months of life. The same infants have the violation of endothelial function to 3 months of age.

[The evaluation of parameters of erythropoiesis and ferrokinetics in children born with extreme low body mass].

The article deals with the results of examination of 51 neonatal infants born with extreme low body mass in terms of gestation 22-31 week at first day of life and in 38-40 weeks of post conception age. The study established lowering of both values of indicators of erythrocyte sprout and level of iron-binding proteins in premature infants with extreme low body mass at birth and at achievement of age of mature infant.

[Characteristics of the population and subpopulation composition of peripheral blood lymphocytes in noncomplicated pregnancy based on flow cytofluorometry data]. / Pokazateli populiatsionnogo i subpopuliatsionnogo sostava limfotsitov perifericheskoi krovi pri neoslozhnennoi beremennosti po materialam protochnoi tsitofliuorometrii.

The population and subpopulation composition of peripheral blood lymphocytes of 33 women was studied in the dynamics of non-complicated pregnancy by the method of flow cytofluorometry with the use of equipment and reagents supplied by Becton Dickinson, Inc. This study revealed that the non-complicated course of pregnancy was characterized by the adequate reaction of the mother's immune system ensuring the physiological development of the fetus during pregnancy and timely labor.