Subject(s)
Bacteria, Anaerobic/metabolism , Hydrogen/metabolism , Iron/metabolism , Microbial Interactions , Acetic Acid/metabolism , Alkalies/chemistry , Alkalies/metabolism , Anaerobiosis , Bacteria, Anaerobic/growth & development , Biodegradation, Environmental , Chromatography, High Pressure Liquid , Ethanol/metabolism , Ferrosoferric Oxide/metabolism , Formates/metabolism , Hydrogen/chemistry , Iron/chemistry , Lactic Acid/metabolism , Mannitol/metabolism , Oxidation-Reduction , Spectroscopy, Mossbauer , Water Pollution, ChemicalABSTRACT
The hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus was found to be capable of lithoautotrophic growth on medium containing molecular hydrogen, sulfate, and amorphous Fe(III) oxide. During the growth of this microorganism, amorphous Fe(III) oxide was transformed into black strongly magnetic sediment rich in magnetite, as shown by Mossbauer studies. Experiments involving inhibition of microbial sulfate reduction and abiotic controls revealed that magnetite production resulted from chemical reactions proceeding at elevated temperatures (83 degrees C) between molecular hydrogen, amorphous Fe(III) oxide, and sulfide formed enzymatically in the course of dissimilatory sulfate reduction. It follows that magnetite production in this system can be characterized as biologically mediated mineralization. This is the first report of magnetite formation as a result of activity of sulfate-reducing microorganisms.
Subject(s)
Archaeoglobus fulgidus/metabolism , Ferric Compounds/metabolism , Iron/metabolism , Oxides/metabolism , Sulfates/metabolism , Archaeoglobus fulgidus/growth & development , Biodegradation, Environmental , Culture Media , Ferrosoferric Oxide , Sulfates/chemistry , TemperatureABSTRACT
The authors studied the activity of a pathological process in the lymph nodes of the mediastinum, by using 67Ga citrate and 99mTc, and pulmonary circulation with MAA-99mTc. Radionuclide studies have established that in new cases of respiratory tuberculosis, the function of lymph nodes recovers by 1.5 times higher than that in pretreated patients. In patients with destructive tuberculosis, pulmonary circulation restores insignificantly and slowly, particularly in a group of pretreated patients. This is explained by the fact that the lung fibrous changes available prior to therapy defy an evolutionary process.
Subject(s)
Lymph Nodes/diagnostic imaging , Tuberculosis, Pulmonary/diagnostic imaging , Citrates/pharmacokinetics , Gallium/pharmacokinetics , Humans , Lung/blood supply , Lung/diagnostic imaging , Lung/pathology , Lymph Nodes/pathology , Microcirculation , Mycobacterium tuberculosis/isolation & purification , Radionuclide Angiography/methods , Radiopharmaceuticals/pharmacokinetics , Technetium/pharmacokinetics , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/pathologyABSTRACT
The paper presents the results of typing by HLA classes I and II antigens in 55 patients with tuberculosis and 85 healthy Tyvians in the Erza District. Republic of Tyva. HLA I and II antigens were determined serologically and polymerase chain reaction, respectively. Tyvian patients with pulmonary tuberculosis had HLA B7 antigen more frequently and HLA B12 antigen less frequently than the controls. The findings suggest that pulmonary tuberculosis is associated with HLA-DRB1 14(6) specificity in this district of the Republic of Tyva. These data may be useful in forming groups at risk for pulmonary tuberculosis in the district under study.
