[Modified dithranol minute therapy of psoriasis vulgaris]. / Modifizierte Dithranol-Minutentherapie der Psoriasis vulgaris.

A modified application of 1% and 2% dithranol was tested in 63 psoriatic patients. There were no differences in efficacy between a very short application time (on/off) and that of 5-10 minutes tried on symmetrical lesions. On the whole, higher concentrations of dithranol (2%) were more effective with both short and longer application times. The dithranol tolerance seems to be better with the on/off-application, especially when the 2% preparation is used. In addition, we found a correlation between tolerance of 2% dithranol and the patient's skin type.

[Hereditary congenital hypotrichosis, Marie Unna type]. / Hypotrichosis congenita hereditaria Marie Unna.

Two patients with hereditary hypotrichosis congenita are reported. The family was affected in five generations. Our patients belong to the same family Marie Unna originally investigated. The histological findings correspond with the clinical picture. In the second case, we suspect an early latent stage of this hair abnormity on account of the condition of the hair as well as our microscopical findings. According to literature, seven families suffering from this disease are known up to now.