ABSTRACT
Metabolic syndrome is associated with an increased risk of cognitive impairment. The purpose of this prospective pilot study was to examine the effects of dance exercise on cognitive function in elderly patients with metabolic syndrome. The participants included 38 elderly metabolic syndrome patients with normal cognitive function (26 exercise group and 12 control group). The exercise group performed dance exercise twice a week for 6 months. Cognitive function was assessed in all participants using the Korean version of the Consortium to Establish a Registry for Alzheimer's disease (CERAD-K). Repeated-measures ANCOVA was used to assess the effect of dance exercise on cognitive function and cardiometabolic risk factors. Compared with the control group, the exercise group significantly improved in verbal fluency (p = 0.048), word list delayed recall (p = 0.038), word list recognition (p = 0.007), and total CERAD-K score (p = 0.037). However, no significance difference was found in body mass index, blood pressure, waist circumference, fasting plasma glucose, triglyceride, and HDL cholesterol between groups over the 6-month period. In the present study, six months of dance exercise improved cognitive function in older adults with metabolic syndrome. Thus, dance exercise may reduce the risk for cognitive disorders in elderly people with metabolic syndrome. Key pointsMetabolic syndrome (MS) is associated with an increased risk of cognitive impairment.Aerobic exercise improves cognitive function in elderly people and contributes to the prevention of degenerative neurological disease and brain damage. Dance sport is a form of aerobic exercise that has the additional benefits of stimulating the emotions, promoting social interaction, and exposing subjects to acoustic stimulation and music.In the present study, dance exercise for a 6-month period improved cognitive function in older adults with MS. In particular, positive effects were observed in verbal fluency, word list delayed recall, word list recognition, and the total CERAD-K score.Our data suggest that the implementation of dance exercise programs may be an effective means of prevention and treatment of cognitive disorders.
ABSTRACT
OBJECTIVE: Visceral adipose tissue (VAT) is presumed to play an important role in the development of metabolic syndrome (MS). The purpose of this study was to evaluate the influence of measurement location of VAT on the cardiometabolic risk factors and the MS in the Korean population. METHODS: To assess abdominal fat distribution, 5 single-slice computed tomography (CT) images were obtained in 470 healthy subjects. The five CT images were obtained at the intervertebral space from L1 to S1 using known anatomical landmarks. Multiple logistic regression analysis was performed to assess the relationship between regional adipose tissue areas and MS. RESULTS: All risk factors were more closely correlated with VAT than subcutaneous adipose tissue (SAT), except waist circumference and blood pressure. Images located at L2-L3 or L3-L4 provided high correlations between VAT area and all cardiometabolic risk factors. The highest adjusted odds (per SD) between VAT and MS were the L2-L3 image in men (OR 4.53) and the L1-L2 in women (OR 4.87), which was higher than measures at L4-L5 (OR 3.22 in men, OR 4.71 in women). However, differences in OR between L1-L2 VAT (OR 4.87) and L4-L5 (OR 4.71) were not great in women. CONCLUSIONS: The results of this study suggest that VAT has a stronger association with MS than ASAT in Korean population regardless of measurement site, and an image located in the upper abdomen (L2-L3 or L3-L4) would be a better predictor of the relationship between VAT and MS in Korean men.
