Subject(s)
Immunologic Deficiency Syndromes/complications , Thymoma/complications , Thymus Neoplasms/complications , Aged , B-Lymphocytes/immunology , CD4-CD8 Ratio , CD4-Positive T-Lymphocytes/immunology , Female , Humans , Immunologic Deficiency Syndromes/immunology , Radiography, Thoracic , Thymoma/immunology , Thymus Neoplasms/immunologyABSTRACT
INTRODUCTION: Bubble formation in insulin pump giving sets is a common problem. We studied change in temperature, change in atmospheric pressure, and vibration as potential mechanisms of bubble formation. METHODS: 5 Animas 2020 pumps with 2â mL cartridges and Inset II infusion systems, 5 Medtronic Paradigm pumps with 1.8â mL cartridge and Quickset and 3 Roche Accu-chek pumps with 3.15â mL cartridges were used. Temperature study: insulin pumps were exposed to a temperature change from 4°C to 37°C. Pressure study: insulin pumps were taken to an altitude of 300â m. Vibration study: insulin pumps were vigorously shaken. All were observed for bubble formation. RESULTS: Bubble formation was observed with changes in temperature and atmospheric pressure. Bubble formation did not occur with vibration. DISCUSSION: Changes in insulin temperature and atmospheric pressure are common and may result in bubble formation. Vibration may distribute bubbles but does not cause bubble formation.