[Correlation between atrial function and functional capacity in highly trained subjects]. / Corrélation entre fonction atriale et capacité fonctionnelle chez les sportifs de haut niveau.

AIM: The aim of the study is to show the relationship existing between tissular Doppler imaging (TDI) parameters and functional capacity in highly trained subjects. METHODS AND PATIENTS: We therefore studied 46 patients including 22 untrained and 24 trained subjects. Each subject had pulsed TDI recording of systolic (S) and diastolic (E and A) longitudinal myocardial velocities in the basal portion of the RV free wall (RV), the septum (sep) and the LV free wall (LV) from apical 4C view. Athletes underwent the same day a cardiopulmonary test during which we measured peak V(O)2 (ml/kg/min) and anaerobic threshold (AT, ml/kg/min) and calculated VE/V(CO)2 slope. We studied differences between echocardiographic parameters in the two groups using Student test. Coefficients of correlations were calculated using the Spearman method. RESULTS: Differences between two groups concerned Tei index of right (RV) and left ventricle (LV), telediastolic diameter of LV, and A waves on each wall. In athletes RV, sep and LV S waves did not correlate with V(O)2, AT or VE/V(CO)2 RV, sep and LV A waves correlated significantly and negatively with V(O)2, RV and sep A waves negatively with AT, and sep and LV A waves positively with VE/V(CO)2. CONCLUSION: In athletes, atrial function shows a negative relationship with cardiopulmonary exercise parameters: the lower the proportion of LV filling due to atrial contraction, the better the level of functional capacity. This is probably due to myocardial structure, which allows more efficient early filling in hypertrophic athlete's heart.

[Long-term clinical benefits of using active stents in diabetic patients: two year follow-up of a consecutive series of 122 patients]. / Bénéfice clinique à long terme de l'utilisation des stents actifs chez les patients diabétiques: suivi à deux ans d'une série consécutive de 122 patients.

The objective of our study is to evaluate the long-term results of coronary angioplasty using active stents in a population of diabetic patients. This is a single-centre study on a consecutive series of 122 diabetic patients (40% of them insulin dependent) who between January 2003 and June 2004 underwent angioplasty with implantation of an active stent (sirolimus Cypher(R) or paclitaxel Taxus(R)) for one or more de novo coronary lesions. The mean age was 66 +/- 10 years and a total of 171 coronary segments were treated. The lesions treated were complex (type B2 + C) in 69% of the cases, with a mean stent length of 21 +/- 15 mm and a mean stent diameter of 2.7 +/- 0.3 mm. Follow-up at two years for 119 patients (3 lost to follow-up) revealed a mortality rate of 4.2%, and a myocardial infarction rate of 7.5%. The rates for revascularisation of the target lesion and the target vessel were 11.4% and 17.8% respectively, with a rate of major cardiac events of 22.5%. During this period, 25.2% of the patients underwent revascularisation of at least one vessel. This study confirms the benefits of using active stents for revascularisation of the target lesion in diabetic patients. However, it serves as a reminder that the progression of coronary atheroma is global, and that the prognosis for these patients depends essentially upon managing risk factors, and particularly on controlling their diabetes.