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2.
Sci Rep ; 14(1): 10719, 2024 05 10.
Article in English | MEDLINE | ID: mdl-38729975

ABSTRACT

The shielding parameters can vary depending on the geometrical structure of the linear accelerators (LINAC), treatment techniques, and beam energies. Recently, the introduction of O-ring type linear accelerators is increasing. The objective of this study is to evaluate the shielding parameters of new type of linac using a dedicated program developed by us named ORSE (O-ring type Radiation therapy equipment Shielding Evaluation). The shielding evaluation was conducted for a total of four treatment rooms including Elekta Unity, Varian Halcyon, and Accuray Tomotherapy. The developed program possesses the capability to calculate transmitted dose, maximum treatable patient capacity, and shielding wall thickness based on patient data. The doses were measured for five days using glass dosimeters to compare with the results of program. The IMRT factors and use factors obtained from patient data showed differences of up to 65.0% and 33.8%, respectively, compared to safety management report. The shielding evaluation conducted in each treatment room showed that the transmitted dose at every location was below 1% of the dose limit. The results of program and measurements showed a maximum difference of 0.003 mSv/week in transmitted dose. The ORSE program allows for the shielding evaluation results to the clinical environment of each institution based on patient data.


Subject(s)
Particle Accelerators , Radiation Protection , Particle Accelerators/instrumentation , Radiation Protection/instrumentation , Radiation Protection/methods , Humans , Radiotherapy, Intensity-Modulated/methods , Radiation Dosage
3.
PLoS One ; 19(4): e0301435, 2024.
Article in English | MEDLINE | ID: mdl-38635642

ABSTRACT

In radiotherapy, when photon energy exceeding 8 MV is utilized, photoneutrons can activate the components within the gantry of the linear accelerator (linac). At the end of the linac's lifecycle, radiation workers are tasked with its dismantling and disposal, potentially exposing them to unintentional radiation. This study aims to identify and measure the radioisotopes generated by this activation through spectroscopy, and to evaluate the effective dose rate. We selected nine medical linacs, considering various factors such as manufacturer (Siemens, Varian, and Elekta), model, energy, period of operation, and workload. We identified the radionuclides in the linac head by employing an in situ high-purity germanium (HPGe) detector. Spectroscopy and dose-rate measurements were conducted post-shutdown. We also measured the dose rates at the beam-exit window following irradiation with 10 MV and 15 MV photon beams. As a result of the spectroscopy, we identified approximately 20 nuclides including those with half-lives of 100 days or longer, such as 54Mn, 60Co, 65Zn, 122Sb, and 198Au. The dose rate measurements after 10 MV irradiation decreased to the background level in 10 min. By contrast, on 15 MV irradiation, the dose rate was 628 nSv/h after 10 min and decreased to 268 nSv/h after 1.5 hours. It was confirmed that the difference in the level of radiation and the type of nuclide depends on the period of use, energy, and workload. However, the type of nuclide does not differ significantly between the linacs. It is necessary to propose appropriate guidelines for the safety of workers, and disposal/move-install should be planned while taking into consideration the equipment's energy usage rate.


Subject(s)
Manganese , Radioisotopes , Humans , Radiotherapy Dosage , Particle Accelerators , Photons , Spectrum Analysis
5.
Phys Eng Sci Med ; 47(2): 443-451, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38224383

ABSTRACT

With the increasing use of flattening filter free (FFF) beams, it is important to evaluate the impact on the skin dose and target coverage of breast cancer treatments. This study aimed to compare skin doses of treatments using FFF and flattening filter (FF) beams for breast cancer. The study established treatment plans for left breast of an anthropomorphic phantom using Halcyon's 6-MV FFF beam and TrueBeam's 6-MV FF beam. Volumetric modulated arc therapy (VMAT) with varying numbers of arcs and intensity modulated radiation therapy (IMRT) were employed, and skin doses were measured at five points using Gafchromic EBT3 film. Each measurement was repeated three times, and averaged to reduce uncertainty. All plans were compared in terms of plan quality to ensure homogeneous target coverage. The study found that when using VMAT with two, four, and six arcs, in-field doses were 19%, 15%, and 6% higher, respectively, when using Halcyon compared to TrueBeam. Additionally, when using two arcs for VMAT, in-field doses were 10% and 15% higher compared to four and six arcs when using Halcyon. Finally, in-field dose from Halcyon using IMRT was about 1% higher than when using TrueBeam. Our research confirmed that when treating breast cancer with FFF beams, skin dose is higher than with traditional FF beams. Moreover, number of arcs used in VMAT treatment with FFF beams affects skin dose to the patient. To maintain a skin dose similar to that of FF beams when using Halcyon, it may be worth considering increasing the number of arcs.


Subject(s)
Breast Neoplasms , Particle Accelerators , Phantoms, Imaging , Radiotherapy Dosage , Radiotherapy, Intensity-Modulated , Skin , Humans , Skin/radiation effects , Female , Breast Neoplasms/radiotherapy , Breast/radiation effects , Breast/diagnostic imaging , Radiotherapy Planning, Computer-Assisted , Dose-Response Relationship, Radiation , Radiation Dosage
6.
Sci Rep ; 13(1): 17994, 2023 Oct 21.
Article in English | MEDLINE | ID: mdl-37865666

ABSTRACT

The purpose of our study is to establish an efficient quality assurance (QA) procedure using a transmission-type detector (IBA, Stealth chamber), a reference signal detector, as a field chamber. Relative dosimetry items, including monitor unit linearity, output constancy based on dose rate and field size, and output factor were measured and compared with results obtained from the Farmer-type chamber (IBA, Wellhofer, FC65-G). Moreover, output for each field size was measured to assess its applicability to small fields. Results using the Stealth chamber were in good agreement with the FC65-G within 1.0%, except for output constancy according to gantry angle, which had a 1.1% error rate for the Stealth chamber and 2.7% for the FC65-G. Differences of up to - 6.26% output factor were observed for the Stealth chamber and up to - 0.56% for the CC-13 ionization chamber (IBA) in the 3 × 3 cm2 field. Our study confirmed the possibility of using Stealth chambers for relative dosimetry measurement in QA.

7.
Phys Eng Sci Med ; 46(3): 1043-1053, 2023 Sep.
Article in English | MEDLINE | ID: mdl-37470930

ABSTRACT

Our study recalculated the use factor of linear accelerators (LINACs) by using an in-house program based on Digital Imaging and Communications in Medicine radiation therapy (DICOM-RT). We considered the impact of advancements and changes in treatment trends, including modality, technology, and radiation dose, on the use factor, which is one of the shielding parameters. In accordance with the methodology described in the NCRP 151 report, we computed the use factor for four linear accelerators (LINACs) across three hospitals. We analyzed the results based on the treatment techniques and treatment sites for three-dimensional conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy or volumetric modulated arc therapy. Our findings revealed that the use factors obtained at 45° and 90° were 14.8% and 13.5% higher than those of the NCRP 151 report. In treatment rooms with a high 3D-CRT ratio, the use factor at a specific angle differed by up to 14.6% relative to the NCRP 151 report value. Our results showed a large difference in the use factor for specific sites such as the breast and spine, so it is recommended that each institution recalculate the use factor using patient's data.


Subject(s)
Radiotherapy, Conformal , Radiotherapy, Intensity-Modulated , Humans , Radiotherapy Planning, Computer-Assisted/methods , Access to Information , Radiotherapy, Conformal/methods , Radiotherapy, Intensity-Modulated/methods , Radiotherapy Dosage
8.
Front Vet Sci ; 9: 832272, 2022.
Article in English | MEDLINE | ID: mdl-35664845

ABSTRACT

Purpose: The purpose of this study is to propose a technique for delivering accurate doses in an image-guided system by developing an experimental setup optimized for total lymphoid irradiation (TLI) in rat lung transplantation. Materials and Methods: In this study, a position-controlled shielding system was developed, and the dose was quantitatively evaluated using a 3D rat phantom and Gafchromic EBT3 film. In addition, we made our own image-guided system that allows the position of the rat and the shielding system to be confirmed during TLI. Results: As a result of using the position-controlled shielding system, it was found that the doses to the head and lungs were reduced by 93.1 and 87.4%, respectively, of the prescribed doses. In addition, it was shown that the position of the shielding system can be easily confirmed by using the image guidance system. Conclusion: A shielding apparatus that can control dose delivery according to the size of the rat can optimize the dose for TLI in rat lung transplantation.

9.
In Vivo ; 36(2): 1013-1017, 2022.
Article in English | MEDLINE | ID: mdl-35241564

ABSTRACT

BACKGROUND/AIM: The purpose of this study was to determine whether a semi-cylindrical beam spoiler (sCBS) developed herein effectively increases the skin dose in patients with early-stage glottic cancer. PATIENTS AND METHODS: We measured the surface doses for 26 patients who used the sCBS during treatment of early-stage glottic cancer through a parallel-opposed lateral two-field 6 MV photon beam. Measurements were performed by attaching optically stimulated luminescent dosimeters to the left, right, anterior (in-field), inferior, and superior (out-field) sides of the patient. RESULTS: The measured results were 81.8±2.1% (left), 81.0±1.7% (right), and 76.8±2.7% (anterior) in the in-field region compared to prescription doses, with 5.7±1.7% (superior) and 2.7±0.7% (inferior) in the out-field region. CONCLUSION: sCBS can deliver a suitably ideal surface dose for treatment of early-stage glottic cancer.


Subject(s)
Laryngeal Neoplasms , Humans , Laryngeal Neoplasms/radiotherapy , Radiotherapy Dosage
10.
ACS Appl Mater Interfaces ; 13(23): 27353-27363, 2021 Jun 16.
Article in English | MEDLINE | ID: mdl-34075756

ABSTRACT

In order to ensure high-performance semitransparent perovskite solar cells (ST-PSCs), the deposition of high-quality scalable transparent cathodes on ST-PSCs at room temperature is necessary. In this study, we designed an amorphous InGaTiO (IGTO) electrode, prepared by linear facing target sputtering (LFTS) as a transparent cathode for ST-PSCs. Even in the room temperature sputtering process, the amorphous IGTO cathode showed a low sheet resistance of 9.895 Ohm/square and a high optical transmittance of 87.53% without the occurrence of in situ or postannealing, unlike Sn-doped In2O3 (ITO) electrodes. Due to its complete amorphous structure and low energy sputtering, the amorphous IGTO electrode showed superior mechanical properties, when compared to other typical crystalline ITO films. Additionally, the LFTS process led to a low energy deposition of the amorphous IGTO cathode on ST-PSCs, and did not result in plasma damage on perovskite active layers, which is often typical in conventional situations of direct current sputtering. On the basis of these optimized plasma damage-free sputtering conditions, we examined the feasibility of LFTS-grown IGTO cathodes for ST-PSCs. In our results, we observed that a similar performance of the ST-PSC with an IGTO cathode with the opaque PSC with Ag cathode, indicated that amorphous IGTO cathode is a prospective transparent cathode for ST-PSCs on both rigid or flexible substrates.

11.
Sci Technol Adv Mater ; 21(1): 435-449, 2020 Jul 22.
Article in English | MEDLINE | ID: mdl-32939169

ABSTRACT

We investigated the characteristics of thermally evaporated fullerene (C60)/Ag/C60 (CAC) multilayer films for use in semi-transparent perovskite solar cells (PSCs) and thin-film heaters (TFHs). The top and bottom C60 layers and Ag interlayer were prepared using multi-source thermal evaporation, and the thickness of the Ag interlayer was investigated in detail for its effects on the resistivity, optical transmittance, and mechanical properties of the CAC electrodes. We used a figure-of-merit analysis to obtain a CAC electrode with a smooth surface morphology that exhibited a sheet resistance of 5.63 Ohm/square and an optical transmittance of 66.13% at a 550 nm wavelength. We conducted mechanical deformation tests to confirm that the thermally evaporated multilayer CAC electrode has a high durability, even after 10,000 times of inner and outer bending, rolling, and twisting due to the flexibility of the amorphous C60 and Ag interlayer. We evaluated the feasibility of using CAC electrodes for semi-transparent PSCs and TFHs. The semi-transparent PSC with 1.08 cm2 active area prepared with a transparent multilayer CAC cathode showed a power conversion efficiency (PCE) of 5.1%. Furthermore, flexible TFHs (2.5 × 2.5 cm2) fabricated on a thermally evaporated CAC electrode show a high saturation temperature of 116.6 C, even at a low input voltage of 4.5 V, due to a very low sheet resistance. Based on the performance of the PSCs and TFHs, we conclude that the thermally evaporated multilayer CAC electrode is promising for use as a transparent conductive electrode (TCE) for semi-transparent PSCs and TFHs, with characteristics comparable to sputtered TCEs.

12.
RSC Adv ; 10(71): 43847-43852, 2020 Nov 27.
Article in English | MEDLINE | ID: mdl-35519689

ABSTRACT

We compared nickel oxide (NiO x ) deposited by thermal evaporation and that deposited by the spin-coating process, for use in the hole transport layers of inverted planar perovskite solar cells (PSCs). Spin-coating deposition for NiO x HTL has been widely used, owing to its simplicity, low cost, and high efficiency. However, the spin-coating process has a technical limit to depositing a large-area uniformly. In contrast, thermal evaporation fabrication has a low price and is able to produce uniform and reproducible thin film. Hence, the chemical states, energy band alignment, surface morphologies, and microstructures of NiO x deposited by spin coating and thermal evaporation were analyzed. The PSC with NiO x HTL deposited by thermal evaporation showed a higher power conversion efficiency of 16.64% with open circuit voltage 1.07 V, short circuit current density of 20.68 mA cm-2, and a fill factor of 75.51% compared to that of PSC with spin-coated NiO x . We confirmed that thermal evaporation can deposit NiO x to give a better performance as a HTL with higher reproducibility than spin-coating.

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