ABSTRACT
The article presents the results of a study that describes the impact of successful Helicobacter pylori infection eradication on the main biochemical markers of metabolic syndrome. It was found that successful anti-helicobacter therapy in patients with MS was accompanied by statistically significant improvement in carbohydrates and lipid metabolism, the liver functional state, lowering hsCRP levels.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Helicobacter Infections/complications , Helicobacter Infections/drug therapy , Helicobacter pylori , Metabolic Syndrome/microbiology , Metabolic Syndrome/prevention & control , Adult , Aged , Biomarkers/metabolism , Female , Humans , Male , Metabolic Syndrome/diagnosis , Metabolic Syndrome/metabolism , Middle Aged , Remission Induction , Young AdultABSTRACT
Cardiovascular diseases are the cause of premature death, but the lifestyle modifications, struggle with the major cardiovascular risk factors can significantly reduce the incidence of coronary events, cerebral vascular lesions and the latter of peripheral arteries. In everyday practice, the elimination of risk factors by the family doctor should be a mandatory part of prevention and treatment programs.
Subject(s)
Cardiovascular Diseases/prevention & control , Family Practice/methods , Practice Patterns, Physicians' , Risk Reduction Behavior , Humans , Physician's Role , Risk FactorsABSTRACT
This article presents an analysis of the traditional risk factors for adverse cardiovascular events in patients with ulcerative colitis. In addition, special attention is given to additional ("new") cardiovascular risk factors.
Subject(s)
Cardiovascular Diseases/epidemiology , Colitis, Ulcerative/epidemiology , Comorbidity , Humans , Risk FactorsABSTRACT
In this article we assessed the positive impact of statins and omega-3 polyunsaturated fatty acids on achieving target lipid levels, acute phase proteins in patients with ulcerative colitis and subclinical atherosclerosis.
Subject(s)
Atherosclerosis/drug therapy , Colitis, Ulcerative/complications , Fatty Acids, Omega-3/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Acute-Phase Proteins/metabolism , Atherosclerosis/etiology , Atherosclerosis/metabolism , Humans , Lipid Metabolism/drug effectsABSTRACT
The pathogenesis of gastric mucosa lesions in elderly and senile people has many factors. It's based on contradiction between protective factors (mucus secretion, prostaglandins, bicarbonate, microcirculation, regeneration, etc.) and aggression factors (hydrochloric acid, pepsin, bile acids, pancreatic enzymes, bacteria). In addition, such important factors as neurohumoral disorders, nutrition and vascularization of the gastric mucosa have attached. The aim of the study was to evaluate the possible relations between microcirculation and data of gastric mucosa transendoscopy thermometry in elderly and senile patients with atherosclerosis confirmed by duplex ultrasound of extracranial brachiocephalic arteries.
Subject(s)
Atherosclerosis/diagnostic imaging , Atherosclerosis/physiopathology , Brachiocephalic Trunk/diagnostic imaging , Gastric Mucosa/physiopathology , Osteoarthritis/diagnostic imaging , Osteoarthritis/physiopathology , Thermometry/methods , Aged , Alzheimer Disease/complications , Atherosclerosis/complications , Gastroscopy/methods , Humans , Microcirculation , Osteoarthritis/complications , Regional Blood Flow , Ultrasonography, Doppler, Duplex/methodsABSTRACT
Article presents the result of assessmaent of cardiovascular risk factors in patients with nonalcoholic fatty liver disease (NAFLD). The results show the presence of cardiovascular risk factors in patients with NAFLD, namely the increase of waist and hip circumferences compared with patients of the control group, hyperglycemia and dyslipidemia, decrease in apolipoprotein A1 (AroA1) compared to practically healthy people.
Subject(s)
Cardiovascular Diseases/epidemiology , Dyslipidemias/epidemiology , Hyperglycemia/epidemiology , Non-alcoholic Fatty Liver Disease/epidemiology , Apolipoprotein A-I/metabolism , Biomarkers/metabolism , Cardiovascular Diseases/metabolism , Case-Control Studies , Comorbidity , Female , Humans , Male , Middle Aged , Non-alcoholic Fatty Liver Disease/metabolism , Risk Factors , Waist CircumferenceABSTRACT
In patients with preasthma and bronchial asthma, short-term courses of fasting dietotherapy (FDT) with a 7-day fasting period proved to be effective, as evidenced by clinical-and-functional and laboratory investigations. The incidence rate of viral infections was much lower with short-term courses compared to long-term courses. Too low an effect, if any, with FDT short-term courses can be explained by excess of the patient's body weight. Short-term FDT courses with a 3-day fasting period have been found out to result in a significant decrease in the level of anxiety, as measured by Spilberger Anxiety Inventory.
Subject(s)
Asthma/diet therapy , Fasting , Adult , Asthma/physiopathology , Female , Humans , MaleABSTRACT
Clinical and functional efficacy of the antileukotriene agent montelucast (singulair) was investigated in 30 patients with moderately severe bronchial asthma. Patients with a positive FEV1 response to montelukast (61.1%) demonstrated a higher blood level of IgE and sputum eosinophilia. Enhancement of bronchodilatatory effect secondary to the use of beta 2-agonist has been recordable in the wake of a 24-day montelucast treatment (10 mg o.d.).
Subject(s)
Acetates/therapeutic use , Asthma/drug therapy , Leukotriene Antagonists/therapeutic use , Quinolines/therapeutic use , Acetates/administration & dosage , Administration, Oral , Adolescent , Adult , Child , Cyclopropanes , Drug Administration Schedule , Eosinophilia/chemically induced , Female , Humans , Immunoglobulin E/blood , Immunoglobulin E/drug effects , Leukotriene Antagonists/administration & dosage , Male , Middle Aged , Quinolines/administration & dosage , Sputum/cytology , Sputum/drug effects , SulfidesABSTRACT
Forty-four patients with bronchial asthma, aside from clinical and functional evaluation, were studied for the psychological profile (MMPI-test) and the presence of antibodies to the lung tissue. The correlations established were as follows: normal titers of antibodies to the lung tissue--more agreeable and satisfactory psychological profile of the patients, the lower or higher the antibody titer, the less acceptable is the psychological profile.
Subject(s)
Asthma/immunology , Asthma/psychology , Autoantibodies/blood , Lung/immunology , Psychophysiologic Disorders/immunology , Psychophysiologic Disorders/psychology , Adolescent , Adult , Female , Humans , MMPI , Male , Middle Aged , PsychoneuroimmunologyABSTRACT
A study is presented of the effect of different modifiers (analogues of natural food) on the rate of starch hydrolysis in the small and large intestine. Revealed were different changes of the activity of amylase and glycyl-l-leucin-dipeptidase under the effect of B vitamins, Enzaprost F., cimetidine, obsidan, prednisolone, dopamine, ethaden, ethanol. Both in vitro and in vivo studies showed that the reactions of changes of the enzymatic activity were of the same direction.
Subject(s)
Intestine, Large/enzymology , Intestine, Small/enzymology , Digestion/drug effects , Digestive System Diseases/drug therapy , Digestive System Diseases/enzymology , Humans , Hydrolysis/drug effects , In Vitro Techniques , Intestine, Large/drug effects , Intestine, Small/drug effects , Starch/metabolismABSTRACT
Parietal measurements of pH values in patients with various intestinal diseases and in normal subjects have revealed that alkaline medium with gradual elevation of the values in the caudal direction is characteristics of the normal large intestine; acid pH values were registered in patients with lactase insufficiency, nonspecific ulcerative colitis, in contrast to those with post-dysentery colitis and tumors of the large intestine. Lactulose and sodium sulfate were found the factors that significantly influence the large intestine parietal pH values, the effects of wheat bran were lower; magnesium sulfate and sodium hydrocarbonate mineral water with medium mineral content had no effect on parietal pH values.
