ABSTRACT
Statines are first choice medications for hypercholesterolemia and combined hyperlipidemia of varying severity in wide population of patients. Atorvastatine is one of the most effective statines. In Russia, Atorvastatine is represented by nearly twenty drugs most of which are generics. The article covers data on efficiency, safety and good tolerance of Liptonorm--a generic Atorvastatine.
Subject(s)
Atorvastatin/pharmacology , Cardiovascular Diseases/blood , Cardiovascular Diseases/drug therapy , Drugs, Generic/pharmacology , Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology , Aged , Atorvastatin/administration & dosage , Atorvastatin/adverse effects , Drugs, Generic/administration & dosage , Drugs, Generic/adverse effects , Female , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects , Male , Middle Aged , Risk , RussiaABSTRACT
The article deals with usage of nondihydropiridine calcium antagonists--verapamil and dilthiasem--in treating patients with arterial hypertension, cardiomyopathy and arrhythmia, for secondary prevention of IHD. Data also concern cardio-, angio--and nephroprotective activity of the medications, their ability to prevent left ventricle hypertrophy, possible usage in patients after myocardial infarction. The authors also discuss problems of tolerance and safety of calcium antagonists with prolonged action vs. those with short-term action.
