1.
Clin Pharmacol Ther
; 59(3): 265-7, 1996 Mar.
Article
in English
| MEDLINE
| ID: mdl-8653988
2.
J Med Chem
; 18(7): 689-91, 1975 Jul.
Article
in English
| MEDLINE
| ID: mdl-1151988
ABSTRACT
Triarylpyridylethanols were prepared by condensing the corresponding diaryl ketones and diarylmethanes. The ethylenes were obtained by the acid-catalyzed elimination of H2O from the ethanols. In the absence of electron-donating substituents, acid treatment of the carbinols resulted in predominant cleavage to starting ketone. The compounds were tested for their antifertility effects in pregnant hamsters. The most active compound was carbinol 3, which, at 30 mg/kg, prevented all of the treated animals from maintaining their pregnancies.
Subject(s)
Contraceptive Agents/chemical synthesis , Ethanol/chemical synthesis , Ethylenes/chemical synthesis , Pyridines/chemical synthesis , Animals , Contraceptive Agents/pharmacology , Cricetinae , Ethanol/pharmacology , Ethylenes/pharmacology , Female , Fetal Death/chemically induced , Pregnancy , Pyridines/pharmacology
3.
J Reprod Fertil
; 19(3): 503-10, 1969 Aug.
Article
in English
| MEDLINE
| ID: mdl-5817745
Subject(s)
Corpus Luteum/drug effects , Estrogens/pharmacology , Gonadotropins/pharmacology , Animals , Corpus Luteum/anatomy & histology , Drug Synergism , Estrus , Female , Follicle Stimulating Hormone/pharmacology , Guinea Pigs , Injections, Subcutaneous , Luteinizing Hormone/pharmacology , Pregnancy , Prolactin/pharmacology
4.
Endocrinology
; 84(6): 1512-6, 1969 Jun.
Article
in English
| MEDLINE
| ID: mdl-5781130
5.
Anat Rec
; 163(3): 359-72, 1969 Mar.
Article
in English
| MEDLINE
| ID: mdl-5774723
6.
Anat Rec
; 163(3): 373-87, 1969 Mar.
Article
in English
| MEDLINE
| ID: mdl-5774724
Subject(s)
Corpus Luteum/drug effects , Pregnancy, Animal , Animals , Estrone/pharmacology , Female , Follicle Stimulating Hormone/pharmacology , Hypophysectomy , Injections, Subcutaneous , Luteinizing Hormone/pharmacology , Mice , Pituitary Gland/physiology , Pregnancy , Progesterone/pharmacology , Prolactin/pharmacology , Vagina/drug effects
7.
J Reprod Fertil
; 16(3): 333-41, 1968 Aug.
Article
in English
| MEDLINE
| ID: mdl-5691791
8.
Endocrinology
; 83(1): 129-36, 1968 Jul.
Article
in English
| MEDLINE
| ID: mdl-5659424
9.
J Anim Sci
; 27(2): 451-65, 1968 Mar.
Article
in English
| MEDLINE
| ID: mdl-5646345
10.
J Anim Sci
; 27(2): 468-71, 1968 Mar.
Article
in English
| MEDLINE
| ID: mdl-5689563
Subject(s)
Cattle/physiology , Ovary/physiology , Pregnancy, Animal/physiology , Reproduction/physiology , Animals , Female , Ovary/abnormalities , Pregnancy
11.
Endocrinology
; 81(3): 542-52, 1967 Sep.
Article
in English
| MEDLINE
| ID: mdl-6033190