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1.
Clin Case Rep ; 12(7): e9036, 2024 Jul.
Article in English | MEDLINE | ID: mdl-39005572

ABSTRACT

Coronary artery aneurysms and ST-segment elevation myocardial infarction are rare in clinical practice, presenting a management challenge. To the best of our knowledge, this case appears to be the first successful percutaneous treatment of a completely obstructed aneurysmal left main coronary artery.

2.
Cureus ; 14(3): e22993, 2022 Mar.
Article in English | MEDLINE | ID: mdl-35415052

ABSTRACT

Background and aims The measurement of the skinfold thickness at various sites with the calipers has remained the traditional method for estimation of body fat percentage (%BF) in clinical practice. Although this technique is relatively inexpensive and easy to learn, there are more chances of errors while measuring the skinfold thickness by this method. Therefore, no single standard prediction formula for the determination of body fat could be fixed. The aim of our study was to use B-mode ultrasound (US) for measuring the subcutaneous fat thickness and the calipers for skinfold thickness, and then compare, correlate, and derive the prediction equations for estimation of %BF by both the techniques. Methods This cross-sectional, observational, monocentric study was conducted on 43 Indian male volunteers aged 18 to 40 years. After collecting anthropometric data (age, height, weight, body mass index, waist circumference, hip circumference, waist-to-hip ratio [WHR], etc.), the skinfold thickness was measured at four standard sites (biceps, triceps, subscapular region, and suprailiac region) with skinfold caliper (SFC) and then B-mode US. The data were analyzed for distribution, and independent t-test was applied to compare the difference between two means of a %BF estimated by both the methods. The prediction equations were developed from anthropometric and skinfold thickness data obtained from both the methods, i.e., SFC and US, by applying stepwise multiple linear regression. Results It was observed that mean values of all the skinfold thicknesses along with the %BF measured by SFC were far more than those measured by US. The %BF measured by US technique (%BF US) was significantly lesser, i.e., 20.69 (SD: 3.126; p < 0.0002), than that of the SFC method (%BF SFC), i.e., 30.38 (SD: 4.634), which is 0.68 % higher. The best prediction equation for the %BF by SFC method was [%BF SFC = -26.154 + 0.208 SFss + 0.374 age + 0.354 SFbi + 32.066 WHR] (R2 = 84.8), where SFss and SFbi are skin fold thicknesses at subscapular and biceps regions, respectively, measured with SFCs, and that by the US method was [%BF US = 0.713 + 0.351 USsi + 0.232 age + 0.248 USss + 0.448 USbi] (R2 = 84.6), where USsi and USss are skinfold measurements at suprailiac and subscapular regions, respectively, measured by US technique. Conclusion In our study, we arrived to the conclusion that even though the estimated %BF by both the methods were found to have a significant correlation with each other, the values were very less in case of the US method. In the prediction equations, it was found that the skinfold thickness at the suprailiac region was not found to be the significant determining factor for estimation of %BF by SFC method as that by the US method. Looking at the lesser sample size with all participants being males, we do not recommend the prediction equations to be used in clinical practice in spite of the high R2 values.

3.
Indian Heart J ; 74(1): 22-27, 2022.
Article in English | MEDLINE | ID: mdl-34883110

ABSTRACT

OBJECTIVE: There is limited evidence on feasibility and safety of only heparin rota-flush(OHRF)solution in rotational atherectomy (RA). We compared the safety and efficacy of OHRF solution with alternative rota-flush (ARF) solution in patients who underwent RA. METHODS: A total of 48 patients who underwent RA were enrolled in the study. In 25 patients OHRF solution and in 23 patients ARF solution was utilized. The study end points were procedural success rateandrota-related adverse cardiovascular event (RRAE) including slow flow, no reflow, bradycardia, and hemodynamic instability. RESULTS: Procedural success was achieved in all patients in both the OHRF and ARF groups. There was no statistically significant difference in RRAE between the two groups(32.0% vs. 34.7%, p = 0.83). CONCLUSION: OHRF solution appears a more simplistic solution while performing rotablation as compared to ARF solution. Side effects such as hypotension and bradycardia can be circumvented with OHRF solution during rotablation.


Subject(s)
Atherectomy, Coronary , Coronary Artery Disease , Vascular Calcification , Atherectomy, Coronary/adverse effects , Coronary Angiography , Coronary Artery Disease/diagnosis , Coronary Artery Disease/etiology , Coronary Artery Disease/surgery , Coronary Vessels/surgery , Heparin , Humans , Retrospective Studies , Treatment Outcome , Vascular Calcification/diagnosis , Vascular Calcification/surgery
4.
J Clin Orthop Trauma ; 10(1): 149-154, 2019.
Article in English | MEDLINE | ID: mdl-30705551

ABSTRACT

BACKGROUND: The purpose of this study was to compare the values of quadriceps angle (Q angle) in relation to age, weight, height, gender, bilateral and postural variations, and strenuous activities on the weight bearing limbs in order to observe its variability. MATERIALS AND METHODS: A total of 450 adult healthy volunteers (150 male students, 150 female students and 150 male labourers) were enrolled in this cross sectional study. Each volunteer had its height, weight and Q angles measured. Q angle was measured in all subjects bilaterally in both supine and standing position with the same goniometer. Comparison of Q angles and various parameters and groups were studied and tabulated. Correlation between age, weight, height and Q angles was determined by Karl Pearson's correlation coefficient. RESULTS: Females had statistically significant higher Q angles in both knees than males of either group, and difference between males of two groups was insignificant. It was more often greater on left side (42.36%) as compared to right, both in males and females. Majority of subjects showed an increase in angle from supine to standing position. There was negative correlation between height and Q angle with both standing and supine position all three groups. Weight and age did not show significant correlation with Q angle. Physical activity did not show any significant effect on the angle. CONCLUSION: Q angle is an important parameter to assess quadriceps muscle's function and its effect on knee. An increase in the angle is clearly associated with patellofemoral problems. Higher Q angle among females may predispose them to sports related injuries. It is important to take into consideration of such factors like sex, height, posture, side, foot rotation and muscle's relaxation while measuring and comparing the angle.

5.
Int J Appl Basic Med Res ; 6(2): 106-10, 2016.
Article in English | MEDLINE | ID: mdl-27127739

ABSTRACT

CONTEXT: In India, the correlation of severity of minor myocardial damage with dyslipidemia has rarely been studied in patients of unstable angina (UA). Dyslipidemia is proven to be a major risk factor for developing acute coronary syndrome (ACS) but still there is doubt about the type of lipoproteins involved in causing minor myocardial damage occurring in UA patients of ACS. AIMS: The aim of our study was to find out the contribution of various types of lipoproteins to predict the severity of minor myocardial damage occurring in the patients of UA. SETTINGS AND DESIGN: Correlation design was used for the study. A single group of individuals was selected. Data were collected on dependent variable creatine kinase-MB (CK-MB) and independent variables (lipid profile parameters). SUBJECTS AND METHODS: The study comprised fifty patients admitted in cardiac care unit with typical history of UA with electrocardiogram showing no ST-segment elevation. The severity of myocardial damage was assessed from on admission CK-MB levels. The lipid profile was estimated from fasting blood samples of all the patients. STATISTICAL ANALYSIS USED: For the purpose of the study, Pearson correlation and multiple linear regression analysis methods were applied. RESULTS: The triacylglycerol (TAG), very-low-density lipoprotein (VLDL), total cholesterol/high-density lipoprotein (TC/HDL) showed significant positive correlation whereas HDL was negatively correlating with CK-MB levels. CONCLUSIONS: The TAG, VLDL, and TC/HDL were found to be significantly affecting the severity of myocardial damage in the patients of UA.

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