Development and validation of an accurate smartphone application for measuring waist-to-hip circumference ratio.

Waist-to-hip circumference ratio (WHR) is now recognized as among the strongest shape biometrics linked with health outcomes, although use of this phenotypic marker remains limited due to the inaccuracies in and inconvenient nature of flexible tape measurements when made in clinical and home settings. Here we report that accurate and reliable WHR estimation in adults is possible with a smartphone application based on novel computer vision algorithms. The developed application runs a convolutional neural network model referred to as MeasureNet that predicts a person's body circumferences and WHR using front, side, and back color images. MeasureNet bridges the gap between measurements conducted by trained professionals in clinical environments, which can be inconvenient, and self-measurements performed by users at home, which can be unreliable. MeasureNet's accuracy and reliability is evaluated using 1200 participants, measured by a trained staff member. The developed smartphone application, which is a part of Amazon Halo, is a major advance in digital anthropometry, filling a long-existing gap in convenient, accurate WHR measurement capabilities.

Subtrochanteric Pathological Femur Fracture in an HIV-Positive Patient on Tenofovir-based antiretroviral therapy: A Case Report and Review of the Literature.

Introduction: The population of people living with human immunodeficiency virus (HIV) and AIDS has increased and so is the incidence of fragility fractures in these patients. Multiple contributory factors are responsible for osteomalacia or osteoporosis in such patients such as a chronic inflammatory response to the HIV, highly active antiretroviral therapy (HAART) itself, and associated comorbidities. Tenofovir has also been reported to disrupt bone metabolism and causes fragility fractures. Case Report: A 40-year-old HIV-positive female came to us with pain in her left hip and was unable to bear weight. She had a history of trivial fall. The patient has been taking tenofovir-associated HAART regimen for the past 6 years and has been compliant. She was diagnosed with a left-side transverse subtrochanteric closed femur fracture. Closed reduction and internal fixation was done using a proximal femur intramedullary nail (PFNA). The latest follow-up shows fracture union and good functional outcomes after treating osteomalacia, and HAART changed to a non-tenofovir regimen later. Conclusion: Patients with HIV infection are prone to fragility fractures and periodic monitoring of their BMD, serum calcium, and vitamin D3 levels should be done for prevention and early diagnosis. More vigilance in patients receiving a tenofovir-associated HAART regimen is needed. Appropriate medical treatment needs to be started once any abnormality in the bone metabolic parameters is detected, and drugs like tenofovir need to be changed as it causes osteomalacia.

Photo generated charge transport studies of defects-induced shuttlecock-shaped ZnO/Ag hybrid nanostructures.

We report the stimulating effects of interfacial charge transfer process between spherical Ag nanoparticles and shuttlecock-shaped ZnO nanostructures observed by UV-visible spectroscopy and x-ray absorption spectroscopy. In specific, ZnO nanorods and shuttlecock-shaped ZnO/Ag nanostructures were developed using a simple chemical colloidal method and characterized for structural variations using XRD. The observed red shift in plasmonic peak and the increase in Urbach energy signify interfacial interactions and increased randomness in the hybrid ZnO/Ag nanostructures. Simultaneously, the enhanced intensity of deep-level emission in the ZnO/Ag hybrid suggests the increased recombination rate of electron-hole pairs. The red and blue emissions evolving with temperature subsequently suggests the presence of oxygen vacancies or zinc interstitials in the system. The decrease in intensities and emerging features in O K-edge and Zn L-edge indicates the charge transfer from Ag to ZnO at the interface of ZnO/Ag hybrids. Moreover, the differences in absorption edges with alternating light on/off conditions were analyzed for the exploitation of this ZnO-based system in various applications.

Synthesis of ZnO@Ag dumbbells for highly efficient visible-light photocatalysts.

The photocatalytic activity (PCA) of ZnO@Ag nanocomposites for different concentrations of Ag is reported. Dumbbells shaped zinc oxide (ZnO) nanostructures with silver (Ag) nanoparticles were synthesized by a simple chemical colloidal method. The as synthesized nanocomposites (without any heat treatment) were used for optical and photocatalytic studies. The FESEM analysis shows that the composite catalysts are composed of ZnO dumbbells coated with spherical Ag nanoparticles. UV-visible spectrum of ZnO@Ag photocatalysts shows a strong absorption band of ZnO at 380 nm with a plasmonic peak of Ag at 440 nm. The PL emission intensity of the composites varies with Ag concentration and has a minimum for the catalyst containing 13.7% of Ag. A possible growth mechanism of ZnO nanostructures with hexagonal cross-section has been proposed. Photocatalytic property of the as synthesized ZnO and ZnO@Ag catalysts was studied by investigating the degradation of methylene blue (MB) dye on exposure to UV-visible radiation. A relatively faster degradation of the dye was observed for ZnO@Ag composites as compared to pure ZnO, showing an improved photocatalytic behavior in the visible region. We proposed a possible mechanism for the enhancement in photocatalytic activity of Ag coated ZnO photocatalysts.