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1.
Indian J Pharm Sci ; 72(4): 531-3, 2010 Jul.
Article in English | MEDLINE | ID: mdl-21218074

ABSTRACT

Triphenyltinbenzoate was synthesized using triphenyltinchloride and silver benzoate prepared from sodium benzoate. The structure of the synthetic compound was elucidated by spectral and C, H analysis. The antibacterial activities of the organotin compound were determined against four bacteria namely Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Streptococcus pyogenes (clinical isolate) and Pseudomonas aeruginosa (ATCC 27853) in vitro experiment. All the bacteria were inhibited at a concentration of 200 µg/ml and 20 µg/ml in dimethylsulphoxide solution and the minimum inhibitory concentration was found to be same, 7.5 µg/ml for Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes and 10 µg/ml for Pseudomonas aeruginosa.

2.
Indian J Pharm Sci ; 71(5): 562-3, 2009 Sep.
Article in English | MEDLINE | ID: mdl-20502579

ABSTRACT

The in vitro toxicity of neem seed oil (Azadirachta indica A. Juss, family: Meliaceae, Dogon yaro in Hausa language in Nigeria) was tested against the larvae of a one-host tick, Boophilus decoloratus (family: Ixodidae or hard tick, commonly known as blue tick) parasitic mainly to cattle generally found in savannas of tropical equatorial Africa. The 20, 40, 60, 80 and 100% concentrations of neem seed oil were found to kill all (100% mortality) the larvae after 27, 27, 27, 27 and 24 h respectively.

3.
Phytother Res ; 13(6): 532-4, 1999 Sep.
Article in English | MEDLINE | ID: mdl-10479769

ABSTRACT

The in vitro toxicity of neem seed oil (Azadiracta indica, family: Meliaceae, 'Dogon yaro' in Hausa -language) was tested against the larvae of a three-host tick, Amblyomma variegatum (family: Ixodidae or hard tick) parasitic to cattle commonly found in Nigeria. Undiluted neem oil (100% concentration) was found to kill all (100% mortality) the larvae after 48 h. The toxicity was concentration and time dependent.


Subject(s)
Cattle Diseases/prevention & control , Plant Oils/toxicity , Tick Control , Tick Infestations/veterinary , Animals , Cattle , Female , Larva/drug effects , Seeds , Tick Infestations/prevention & control , Ticks/drug effects
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