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1.
Heliyon ; 10(7): e28589, 2024 Apr 15.
Article in English | MEDLINE | ID: mdl-38590897

ABSTRACT

Actinotignum schaalii affects elderly people and is associated with individuals with urological-related predispositions, but can be found in a variety of locations, such as cutaneous, intraabdominal, genitourinary and surgical infections. Disseminated infections occur less frequently and are by and large related to urinary tract colonisation. This pathogen is often neglected due to growth requirements, especially in urinary tract infections. We present 107 Actinotignum schaalii isolated from genitourinary samples (80.4%), from skin and soft tissue infections (13.1%), from bone and deep tissue infection (4.7%) and from blood cultures (1.9%). The automated system Alfred 60/AST was paramount for the isolation of 77.6% of the UTI. All the isolates tested were susceptible to penicillin, ampicillin, linezolid, vancomycin, teicoplanin, rifampicin and tetracycline. In conclusion, we present a large series of Actinotignum schaalii infections. This pathogen is hard to isolate, and is resistant to commonly used empirical antimicrobials.

2.
Diagn Microbiol Infect Dis ; 87(4): 318-319, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28139278

ABSTRACT

Bacteria use bicarbonate as substrate for crucial metabolic reactions. We report the first case of bacteremia by capnophilic E. coli without the YadF gene (also known as CynT2 or Can2) that needs high concentrations of CO2 to non-enzymatically produce bicarbonate. This lack may also apply to previously reported capnophilic Enterobacteriaceae.


Subject(s)
Bacteremia/microbiology , Bicarbonates/metabolism , Enterobacteriaceae/metabolism , Aged , Carbon Dioxide/metabolism , Carbonic Anhydrases/metabolism , Escherichia coli Proteins/metabolism , Humans , Male
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