ABSTRACT
Acrokeratoelastoidosis (AKE) is a rare skin disorder characterized by a papular eruption and fragmentation of elastic tissue that primarily involves the margins of the hands and feet. The most common histopathologic findings of AKE are hyperkeratosis and degeneration of elastic fibers. Various treatment options have been tried with little help or without success. We report the third case of acrokeratoelastoidosis in an Arabic woman localized exclusively to the feet.
Subject(s)
Foot Dermatoses/diagnosis , Keratosis/diagnosis , Adult , Cytoplasmic Granules/ultrastructure , Elastic Tissue/pathology , Female , Fibroblasts/pathology , Foot Dermatoses/genetics , Foot Dermatoses/pathology , Genes, Dominant , Humans , Keratosis/genetics , Keratosis/pathologyABSTRACT
Darier disease is an uncommon genodermatosis characterized by verrucous papules in a seborrheic distribution. The linear form of this disease is rare and could result from genetic mosaicism in this autosomal dominant disorder. We report a case of linear Darier disease that involved the right lower limb with a zosteriform distribution.