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2.
Cancer Radiother ; 11(8): 500-2, 2007 Dec.
Article in French | MEDLINE | ID: mdl-17959408

ABSTRACT

Gingival metastases are very rare. We report the case of a 47 year-old man presenting with a gingival metastasis from a non small cell lung carcinoma. According to the literature, the most probable way of spread of such metastasis is haematogenous. Local implantation of cancer cells, present in patient's expectorations, in a fragile gingiva may be an other pathway of lung cancer metastasizing in this region as we will try to describe in this case report. Cytological and/or histological investigation is needed to assess the malignant and the metastatic character of these gingival lesions. A rapid regression is observed after a flash of external beam radiation; nevertheless metastasis prognosis depends on the primary tumour progress.


Subject(s)
Carcinoma, Non-Small-Cell Lung/pathology , Gingival Neoplasms/secondary , Lung Neoplasms/pathology , Neoplasm Metastasis , Carcinoma, Non-Small-Cell Lung/blood , Humans , Lung Neoplasms/blood , Male , Middle Aged , Radiotherapy Dosage
3.
Cancer Radiother ; 10(3): 142-4, 2006 May.
Article in French | MEDLINE | ID: mdl-16309942

ABSTRACT

We report three cases of Hodgkin's disease (HD) involving the nasopharynx. Their clinical presentations, morphological and immunohistochimical features and their therapy modalities are discussed. The patients were aged 36, 41 and 77, presenting with increasing bilateral nasal obstruction in one case and a cervical mass in the two others. Histological study showed mixed cellularity type of HD in all cases. The Reed Sternberg cells expressed both of CD15 and CD30 in one case, and only one of them in the other cases. In one case, LMP1 was detected, CD20 and CD3 were not. HD of nasopharynx should be differentiated from EBV-associated lymphoproliferations. The treatment is based on radiotherapy that can be associated to neoadjuvant chemotherapy if nodes are involved.


Subject(s)
Hodgkin Disease , Nasopharyngeal Neoplasms , Adult , Aged , Female , Hodgkin Disease/diagnosis , Hodgkin Disease/radiotherapy , Humans , Male , Nasopharyngeal Neoplasms/diagnosis , Nasopharyngeal Neoplasms/radiotherapy
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