ABSTRACT
BACKGROUND: Kidneys from child donors are very efficient at adapting to the recipient organism. This research aims to verify the size of kidney grafts from pediatric donors after transplant and to identify factors responsible for the size attained by these kidneys. Moreover, it aims to seek relationships between size and function of the transplanted pediatric kidney. METHODS: Seventy-seven renal transplants performed at least 6 months earlier, with cadaver donor 15 years old or younger, had ultrasound measurements of the graft and renal function assessment. Potential factors for graft volume were analyzed using bivariate analysis, followed by multiple linear regression. RESULTS: After a follow up of 4.2+/-3.3 years posttransplant, the grafts presented the following range of measures: length 10.61+/-1.13 cm, width 4.67+/-0.84 cm, and depth 4.76+/-0.99 cm. Graft volumes were 126.62+/-47.76 cm. Bivariate analysis showed that (1) age of both donor and recipient at transplantation; (2) sex of recipient; (3) occurrence of acute rejection episodes were statistically significant. After multivariate analysis, age and sex of recipients were the only significant factors influencing graft volume; child kidneys reached greater volumes when transplanted into adult and male individuals. Larger volume kidneys presented significantly more proteinuria. No difference was evident with regard to creatinine clearance values or urinary retinol binding protein among kidneys of differing sizes. CONCLUSIONS: The size of the recipient (age and sex) is the main factor responsible for volumes achieved by kidneys from pediatric donors. The volume attained by these kidneys demonstrated no relationship with glomerular or tubular function of the organ.
Subject(s)
Kidney Transplantation/physiology , Adolescent , Adult , Age Distribution , Cadaver , Child , Child, Preschool , Cohort Studies , Female , Follow-Up Studies , Humans , Infant , Kidney/anatomy & histology , Kidney/diagnostic imaging , Male , Middle Aged , Organ Size , Postoperative Complications/classification , Postoperative Complications/epidemiology , Reoperation/statistics & numerical data , Retrospective Studies , Tissue Donors , Ultrasonography , Urinary Tract Infections/epidemiologyABSTRACT
Sao analisadas, retrospectivamente, através de exame ultra-sonográfico, as alteraçoes no comprimento do tendao patelar de 30 pacientes submetidos à reconstruçao intra-articular do ligamento cruzado anterior do joelho usando este tendao como enxerto livre. Foram selecionados somente pacientes que nao se queixavam de dor no joelho operado e que nao apresentaram nenhuma complicaçao pós-operatória. Observou-se que em 50 por cento dos casos houve aumento no comprimento do tendao e que em dois (6,6 por cento) pacientes ele foi maior do que 10 por cento. Em relaçao à outra metade, em cinco (16,7 por cento) pacientes nao houve variaçao no tamanho do tendao patelar em comparaçao com o lado nao operado, enquanto nos outros dez (33,3 por cento) houve diminuiçao, com nenhuma variaçao superior a 10 por cento. Na análise dos dados, nenhuma diferença citada foi estatisticamente significante.
