1.
Seizure
; 12(7): 483-9, 2003 Oct.
Article
in English
| MEDLINE
| ID: mdl-12967577
ABSTRACT
In children, non-convulsive status epilepticus (NCSE) is rare and difficult to treat. Response to steroids and GABAergic medication is variable and often decreases with increasing duration of NCSE. We present our experience with oral ketamine, an NMDA-receptor antagonist, administered to five children with severe epilepsy (Lennox-Gastaut Syndrome, myoclonic-astatic epilepsy, progressive myoclonic epilepsy and Pseudo-Lennox Syndrome) during an episode of NCSE. Resolution of NCSE was documented in all cases clinically and electroencephalographically within 24-48 hours of starting ketamine. No significant side effects were noted.
Subject(s)
Excitatory Amino Acid Antagonists/therapeutic use , Ketamine/therapeutic use , Status Epilepticus/drug therapy , Administration, Oral , Child , Child, Preschool , Electroencephalography/drug effects , Female , Humans , Male , Motor Skills/drug effects , Status Epilepticus/physiopathology , Time Factors
2.
Neuropediatrics
; 31(1): 47-8, 2000 Feb.
Article
in English
| MEDLINE
| ID: mdl-10774998