Disability and physical activity in people with chronic disease receiving physiotherapy. A prospective cohort study.

Chronic disease affects patients' disability and participation in activities of daily living. Longitudinal information on disability and physical activity is generally scarce in patients with chronic disease. The current study aimed to investigate if self-reported disability and physical activity changed in patients with chronic disease receiving physiotherapy. Furthermore, the aim was to assess if an improvement in self-reported disability was related to an increase in objectively measured physical activity and if an aggravation in self-reported disability was related to a decrease in physical activity. Seventy patients with either multiple sclerosis, Parkinson's disease, rheumatoid arthritis or stroke receiving free of charge physiotherapy were tested at baseline and 1 year later. Disability was measured with the self-reported modified Ranking Scale-9 Questionnaire and physical activity was objectively measured using tri-axial accelerometry. Neither self-reported disability nor physical activity changed among patients receiving 1 year of free of charge physiotherapy at group level. Furthermore, self-reported change of disability was not expressed with changes in objectively measured physical activity, indicating that the two measures represent two different constructs.

Effectiveness of stratified treatment for back pain in Danish primary care: A randomized controlled trial.

BACKGROUND: A randomized controlled trial (RCT) of stratified care demonstrated superior clinical outcomes and cost-effectiveness for low back pain (LBP) patients in UK primary care. This is the first study in Europe, outside of the original UK study, to investigate the clinical efficacy and cost-effectiveness of stratified care compared with current practice for patients with non-specific LBP. METHODS: The study was a two-armed RCT. Danish primary care patients with LBP were randomized to stratified care (n = 169) or current practice (n = 164). Primary outcomes at 3- and 12-months' follow-up were Roland Morris Disability Questionnaire (RDMQ), patient-reported global change and time off work. Secondary outcomes included pain intensity, patient satisfaction, healthcare resource utilization and quality-adjusted life years. RESULTS: Intention-to-treat analyses found no between-group difference in RMDQ scores at 3 months (0.5, 95% CI -1.8 to 0.9) or 12 months (0.4, -2.1 to 1.3). No overall differences were found between the arms at 3 and 12 months with respect to time off work or secondary outcomes. Stratified care intervention resulted in significantly fewer treatment sessions (3.5 [SD 3.1] vs. 4.5 [3.5]) and significantly lower total healthcare costs (€) (13.4 [529] vs. 228 [830], p = .002). There was no difference in cost-effectiveness (0.09, 0.05 to 0.13 vs. 0.10, 0.07-0.14, p = .70). CONCLUSIONS: There was no significant difference in clinical outcomes between patients with non-specific LBP receiving stratified care and those receiving current practice. However, stratified care may reduce total healthcare costs if implemented in Danish primary care. SIGNIFICANCE: Stratified care for low back pain based on risk profile is recommended by recent evidence based clinical guidelines. This study is the first broad replication of the STarT Back Trial in Europe. Therefore, the study adds to the body of knowledge evaluating the effectiveness of stratified care for low back pain in primary care, and provides insight into the effects of stratification on clinical practice.

German translation, cross-cultural adaptation and validation of the Musculoskeletal Health Questionnaire: a cohort study.

BACKGROUND: The Musculoskeletal Health Questionnaire (MSK-HQ) was developed to measure the health status of patients with various musculoskeletal conditions across multiple settings including rehabilitation. AIM: Formal translation and cross-cultural adaptation of the MSK-HQ into German (MSK-HQG), to determine test-retest-reliability, standard error of measurement (SEM), smallest detectable change (SDC), construct validity, responsiveness, minimal important change (MIC), and to test for floor or ceiling effects. DESIGN: Cohort study with six weeks follow-up. SETTING: Seven physiotherapy clinics/rehabilitation centres. POPULATION: Patients with a referral for physiotherapy indicating musculoskeletal complaints of the spine or extremities. METHODS: Translation and cross-cultural adaptation were carried out in accordance with guidelines provided by the developers. As reference standards we used pain intensity (0-10 numeric rating scale), quality of life (EQ5D-5L) and disability measures (RMDQ, NDI, WOMAC and SPADI) that were combined using z-scores. RESULTS: On 100 patients (age 44.8±13.4 years, 66% female) the test-retest-reliability intraclass correlation coefficient was 0.87 (95% CI 0.72; 0.93) and for construct validity correlation with the combined disability measure was rs=-0.81 (95% CI -0.88, -0.72), the SEM was 3.4, the SDC (individual) 9.4, and the MIC 8.5. CONCLUSIONS: Overall, the study provides evidence for good reliability and validity for the MSK-HQG. Further studies in different settings and diagnostic subgroups should follow to better understand the psychometric properties of this measure in primary care, rehabilitation and specialist care settings. CLINICAL REHABILITATION IMPACT: The results demonstrate that the MSK-HQG has sufficient psychometric properties for use in musculoskeletal research and practice. However, the SDC should be kept in mind when using the tool for individual patients. The MSK-HQG has the advantage of being a single instrument that can measure musculoskeletal health status across different pain sites, reducing the burden from the use of multiple tools.

Measurement properties of the Fear-Avoidance Belief Questionnaire for physical activity in patients with shoulder impingement syndrome.

BACKGROUND: The Fear-Avoidance Belief Questionnaire for physical activity (FABQ-PA) was originally developed for patients with low-back pain. Whether the FABQ-PA is suitable for use among patients with other musculoskeletal disorders has been sparsely evaluated. PURPOSE: To evaluate test-retest reliability, measurement error, construct validity, and responsiveness of the FABQ-PA in patients with shoulder impingement syndrome (SIS). METHODS: This prospective cohort study included 45 patients with SIS. Data were collected with questionnaires at baseline, after 2-4 days, and at 3 months, which included the Danish versions of the FABQ-PA and the Oxford Shoulder Score (OSS). Test-retest reliability was assessed by intraclass correlation, and standard error of measurement was estimated and converted into the minimal detectable change (MDC). Construct validity was investigated by analyzing the correlation between the baseline scores of the FABQ-PA and the OSS. Responsiveness was investigated from longitudinal construct validity using a correlation analysis reflecting changes over time. RESULTS: Test-retest reliability showed an intraclass correlation of 0.80, and examination of the measurement error showed no systematic differences and a MDC of 7.95 (95% CI 6.57-10.07). Construct validity showed a correlation of -0.60 (95% CI -0.76 to -0.37) between the FABQ-PA and OSS at baseline. A weaker correlation between FABQ-PA- and OSS-change scores was observed (-0.43, 95% CI -0.67 to -0.12). CONCLUSION: The Danish version of the FABQ-PA is suitable for assessing fear-avoidance beliefs in groups of patients with SIS, but its ability to evaluate individual patients and changes over time may be more limited.

The smallest worthwhile effect of primary care physiotherapy did not differ across musculoskeletal pain sites.

OBJECTIVES: To determine and compare estimates of the smallest worthwhile effect (SWE) for physiotherapy in neck, shoulder, and low-back pain patients and to investigate the influence of sociodemographic, clinical, and psychological factors on these estimates. METHODS: A structured telephone interview was conducted before treatment was commenced in 160 patients referred for primary care physiotherapy. The benefit-harm trade-off method was used to estimate the SWE of physiotherapy for the following outcomes; pain, disability, and time to recovery, compared with the improvement achieved without any treatment (natural course). Regression analyses were used to assess the influence of sociodemographics, clinical variables, and intake scores on pain, disability, and psychological scales. RESULTS: The median SWE for improvements on pain and disability was 20% (interquartile range 10%-30%), and the SWE for time to recovery was 10 days (interquartile range 7-14 days) over a period of 6 weeks. These estimates did not differ with respect to pain location (neck, shoulder, or back) and were generally unaffected by sociodemographic, clinical, and psychological factors. CONCLUSION: People with neck, shoulder, and low-back pain need to see at least 20% of additional improvement on pain and disability compared with natural recovery to consider that the effect of physiotherapy is worthwhile, given its costs, potential side effects, and inconveniences.

Shoulder function and work disability after decompression surgery for subacromial impingement syndrome: a randomised controlled trial of physiotherapy exercises and occupational medical assistance.

BACKGROUND: Surgery for subacromial impingement syndrome is often performed in working age and postoperative physiotherapy exercises are widely used to help restore function. A recent Danish study showed that 10% of a nationwide cohort of patients retired prematurely within two years after surgery. Few studies have compared effects of different postoperative exercise programmes on shoulder function, and no studies have evaluated workplace-oriented interventions to reduce postoperative work disability. This study aims to evaluate the effectiveness of physiotherapy exercises and occupational medical assistance compared with usual care in improving shoulder function and reducing postoperative work disability after arthroscopic subacromial decompression. METHODS/DESIGN: The study is a mainly pragmatic multicentre randomised controlled trial. The trial is embedded in a cohort study of shoulder patients referred to public departments of orthopaedic surgery in Central Denmark Region. Patients aged ≥18-≤63 years, who still have shoulder symptoms 8-12 weeks after surgery, constitute the study population. Around 130 participants are allocated to: 1) physiotherapy exercises, 2) occupational medical assistance, 3) physiotherapy exercises and occupational medical assistance, and 4) usual care. Intervention manuals allow individual tailoring. Primary outcome measures include Oxford Shoulder Score and sickness absence due to symptoms from the operated shoulder. Randomisation is computerised with allocation concealment by randomly permuted block sizes. Statistical analyses will primarily be performed according to the intention-to-treat principle. DISCUSSION: The paper presents the rationale, design, methods, and operational aspects of the Shoulder Intervention Project (SIP). SIP evaluates a new rehabilitation approach, where physiotherapy and occupational interventions are provided in continuity of surgical episodes of care. If successful, the project may serve as a model for rehabilitation of surgical shoulder patients. TRIAL REGISTRATION: Current Controlled Trials ISRCTN55768749.

Responsiveness of a Danish version of the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire.

INTRODUCTION: This prospective cohort study in consecutive shoulder patients sought to determine the minimal, clinically important difference of the Danish version of the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and to evaluate patient responsiveness to it. The study was undertaken at the Outpatient Clinic of the Department of Orthopaedic Surgery, Viborg Regional Hospital, Denmark. MATERIAL AND METHODS: During clinical examination, patients completed a baseline questionnaire including the DASH questionnaire, the EuroQol-5D index and the EuroQol-VAS. A follow-up questionnaire concerning the patient's global impression of change was posted to the patients eight to nine weeks after the initial assessment. Responsiveness was analysed by correlation analysis and receiver-operating characteristic curve statistics. Using the optimal cut-off point of the receiver-operating characteristic curve, the minimal, clinically important difference was determined. RESULTS: A total of 81 patients with a variety of shoulder diagnoses were included. Only the DASH questionnaire demonstrated significant differences in change scores (p = 0.001). The area under the curve was 0.76 (95% confidence interval 0.62-0.90), and a minimal clinically important difference of 12 points was found. CONCLUSION: The DASH questionnaire provides a response outcome measure in Danish-speaking orthopaedic shoulder patients. FUNDING: This work was supported by the Regional Hospital of Central Jutland Research Foundation. TRIAL REGISTRATION: not relevant.

The Danish version of the modified Constant-Murley shoulder score: reliability, agreement, and construct validity.

STUDY DESIGN: Test-retest study. Objectives To assess the reliability, agreement, and validity of the Danish version of the modified Constant-Murley score (CMS). BACKGROUND: Modified CMS guidelines were published in 2008. These modifications have recently been translated and cross-culturally adapted into a Danish version. However, the reliability and the validity of this version have yet to be established. METHODS: A total of 45 patients with shoulder impingement syndrome were examined by 2 raters using the modified version of the CMS and a questionnaire that included the Oxford shoulder score. Both raters had a minimum of experience using the CMS. Intrarater and interrater agreement and reliability were examined and compared. Construct validity was assessed by the correlation between the scores of the CMS and the Oxford shoulder score. RESULTS: The minimal detectable change was estimated to be 13 and 11 points for raters A and B, respectively. The intraclass correlation coefficient was 0.93 for rater A and 0.95 for rater B. Interrater comparison demonstrated a minimal detectable change of 12 points and an intraclass correlation coefficient of 0.94. The correlation coefficient between the CMS and the Oxford shoulder score was 0.76. CONCLUSION: The intrarater and interrater reliability and agreement of the Danish version of the modified CMS were found to be acceptable, and construct validity was confirmed.

Effect of brief daily resistance training on rapid force development in painful neck and shoulder muscles: randomized controlled trial.

OBJECTIVE: To determine the effect of small daily amounts of progressive resistance training on rapid force development of painful neck/shoulder muscles. METHODS: 198 generally healthy adults with frequent neck/shoulder muscle pain (mean: age 43.1 years, computer use 93% of work time, 88% women, duration of pain 186 day during the previous year) were randomly allocated to 2- or 12 min of daily progressive resistance training with elastic tubing or to a control group receiving weekly information on general health. A blinded assessor took measures at baseline and at 10-week follow-up; participants performed maximal voluntary contractions at a static 90-degree shoulder joint angle. Rapid force development was determined as the rate of torque development and maximal muscle strength was determined as the peak torque. RESULTS: Compared with the control group, rate of torque development increased 31.0 Nm s(-1) [95% confidence interval: (1.33-11.80)] in the 2-min group and 33.2 Nm s(-1) (1.66-12.33) in the 12-min group from baseline to 10-week follow-up, corresponding to an increase of 16.0% and 18.2% for the two groups, respectively. The increase was significantly different compared to controls (P<0.05) for both training groups. Maximal muscle strength increased only ~5-6% [mean and 95% confidence interval for 2- and 12-min groups to control, respectively: 2.5 Nm (0.05-0.73) and 2.2 Nm (0.01-0.70)]. No significant differences between the 2- and 12-min groups were evident. A weak but significant relationship existed between changes in rapid force development and pain (r = 0.27, P<0.01), but not between changes in maximal muscle strength and pain. CONCLUSION: Small daily amounts of progressive resistance training in adults with frequent neck/shoulder pain increases rapid force development and, to a less extent, maximal force capacity.

Cross-cultural adaption and measurement properties of the Danish version of the Shoulder Pain and Disability Index.

OBJECTIVE: To cross-culturally adapt the Danish version of the Shoulder Pain and Disability Index and to evaluate its measurement properties in terms of reliability and known-group validity. DESIGN: Test-retest study. SETTING: Outpatient Clinic of the Department of Orthopaedic Surgery, Regional Hospital Herning, Denmark. SUBJECTS: Consecutive shoulder patients referred to an outpatient clinic. METHODS: The Shoulder Pain and Disability Index was translated from English into Danish according to international guidelines. The questionnaire was posted to patients one to two weeks before their scheduled clinical examination and repeated on the day of the examination. RESULTS: A total of 65 patients with a variety of shoulder diagnoses were included in the study. No significant differences were found in scores between the first and the second questionnaire. The minimal detectable change was estimated to 19.4 points, and the intraclass correlation coefficient was 0.88 (95% confidence interval 0.83 to 0.94). Internal consistency measured by Cronbach's alpha was 0.94. The questionnaire was found to discriminate well between currently working and non-working patients. CONCLUSION: The Shoulder Pain and Disability Index provides a sensitive and reliable tool to assess pain and disability in Danish-speaking orthopaedic shoulder patients.

Subgroup analyses on return to work in sick-listed employees with low back pain in a randomised trial comparing brief and multidisciplinary intervention.

BACKGROUND: Multidisciplinary intervention is recommended for rehabilitation of employees sick-listed for 4-12 weeks due to low back pain (LBP). However, comparison of a brief and a multidisciplinary intervention in a randomised comparative trial of sick-listed employees showed similar return to work (RTW) rates in the two groups. The aim of the present study was to identify subgroups, primarily defined by work-related baseline factors that would benefit more from the multidisciplinary intervention than from the brief intervention. METHODS: A total of 351 employees sick-listed for 3-16 weeks due to LBP were recruited from their general practitioners. They received a brief or a multidisciplinary intervention. Both interventions comprised clinical examination and advice by a rehabilitation doctor and a physiotherapist. The multidisciplinary intervention also comprised assignment of a case manager, who made a rehabilitation plan in collaboration with the patient and a multidisciplinary team. Using data from a national database, we defined RTW as no sickness compensation benefit disbursement for four consecutive weeks within the first year after the intervention. At the first interview in the clinic, it was ensured that sick leave was primarily due to low back problems.Questionnaires were used to obtain data on health, disability, demographic and workplace-related factors. Cox hazard regression analyses were used with RTW as outcome measure and hazard rate ratios (HRR = HRmultidisciplinary/HRbrief) were adjusted for demographic and health-related variables. An interaction term consisting of a baseline variable*intervention group was added to the multivariable regression model to analyse whether the effects of the interventions were moderated by the baseline factor. Subsequently, a new study was performed that included 120 patients who followed the same protocol. This group was analyzed in the same way to verify the findings from the original study group. RESULTS: The multidisciplinary intervention group ensured a quicker RTW than the brief intervention group in a subgroup with low job satisfaction, notably when claimants were excluded. The opposite effect was seen in the subgroup with high job satisfaction. When claimants were excluded, the effect was also in favour of the multidisciplinary intervention in subgroups characterised by no influence on work planning and groups at risk of losing their job. Inversely, the effect was in favour of the brief intervention in the subgroups who were able to influence the planning of their work and who had no risk of losing their job due to current sick leave. Interaction analysis of the data in the new study displayed similar or even more pronounced differences between subgroups in relation to intervention type. CONCLUSIONS: Multidisciplinary intervention seemed more effective than brief intervention in subgroups of patients with low job satisfaction, no influence on work planning and feeling at risk of losing their jobs due to their sick leave as compared with subgroups not fulfilling these criteria.