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1.
Eur J Clin Nutr ; 58(9): 1314-8, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15054408

ABSTRACT

AIM: To evaluate selenium (Se) and copper (Cu) concentrations in Greek and Albanian immigrant mothers and in the cord blood of their newborns. SUBJECTS AND METHODS: From 1118 Greek and 820 Albanian mothers and from the cord blood of their neonates blood was obtained for Se and Cu measurement. Se and Cu concentrations were determined in sera with graphite furnace atomic absorption spectroscopy (GFAAAS) and atomic absorption spectrometry, respectively. In all, 30 days' nutrient intakes were evaluated in both groups. RESULTS: Animal protein, Se and Cu intakes were poor in the Albanians vs the Greeks (P < 0.001). Se concentrations in the Greek mothers (68.3 +/- 8.5 microg/l) and in their newborns (37.02 +/- 8.9 microg/l) were found higher as compared with those in Albanian mothers (37.4 +/- 9.9 microg/l) and in their newborns (34.3 +/- 9.1 microg/l) (P < 0.001). Cu levels were also found higher (P < 0.001) in the Greek mothers (1687 +/- 353 microg/l) and in their neonates (449 +/- 87 microg/l) compared with those in the Albanian mothers (959 +/- 318 microg/l) and in their newborns (229 +/- 67 microg/l). Additionally, 31.5% of neonates born to Albanian women with Se concentrations less than 28 microg/l had higher Se levels (P < 0.01) than their mothers. CONCLUSIONS: The low Se and Cu levels evaluated in the Albanian mothers and their newborns could be related to their poor animal protein intake which could be the consequence of their low socioeconomic status. As an effective preventive measure, accurate dietetic strategies to assess the requirements of pregnant immigrant women for trace elements may be planned in Greece.


Subject(s)
Copper/blood , Dietary Proteins/administration & dosage , Fetal Blood/chemistry , Infant, Newborn/blood , Pregnancy/blood , Selenium/blood , Adult , Albania/ethnology , Animals , Copper/deficiency , Emigration and Immigration , Female , Greece , Humans , Maternal-Fetal Exchange , Meat , Nutritional Requirements , Nutritional Status , Pregnancy/ethnology , Selenium/deficiency , Socioeconomic Factors , Spectrophotometry, Atomic , Spectrum Analysis
2.
Clin Microbiol Infect ; 9(7): 704-7, 2003 Jul.
Article in English | MEDLINE | ID: mdl-12925112

ABSTRACT

The susceptibilities to macrolides and telithromycin of 161 Streptococcus pyogenes and 145 Streptococcus pyogenes strains, consecutively isolated from five Greek hospitals, were determined by Etest. Moreover, mechanisms of resistance to macrolides were phenotypically and genetically determined by double disk induction test and PCR, respectively. Of the S. pneumoniae and S. pyogenes isolates, 42.8% and 30.8%, respectively, were found to be resistant to erythromycin. Of the erythromycin-resistant S. pneumoniae and S. pyogenes isolates, 57.5% and 59.5%, respectively, displayed the M phenotype and harbored the mefA/E gene. Telithromycin was found to be more active than both erythromycin and clarithromycin against both species, with considerably lower MIC50 and MIC90 values.


Subject(s)
Anti-Bacterial Agents/pharmacology , Drug Resistance, Bacterial , Ketolides , Macrolides , Streptococcus pneumoniae/drug effects , Streptococcus pyogenes/drug effects , Clarithromycin/pharmacology , Dose-Response Relationship, Drug , Erythromycin/pharmacology , Greece
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