ABSTRACT
Gastrointestinal metastasis of pleomorphic lung cancer presents with nonspecific manifestations, leading to delayed diagnosis. Herein, the authors report the case of a 56-year-old patient who presented with gastrointestinal bleeding due to pleomorphic lung carcinoma. Case presentation: A 56-year-old patient presented to the emergency department with melena. On examination, he was hemodynamically stable. He had a sensitive and mobile mass in the periumbilical region. A thoracoabdominal computed tomography scan showed a mass of the right apical superior lobe measuring 4 cm and a lobulated jejunal mass measuring 10 cm. A percutaneous biopsy of the lung tumor revealed primary pleomorphic lung carcinoma. The authors performed a midline laparotomy and made a bowel resection with an end-to-end anastomosis. The postoperative course was marked by severe nosocomial pneumonia, leading to septic shock and death. The histopathologic examination concluded with a metastatic lesion of pleomorphic lung carcinoma. Clinical discussion: The authors reported a rare case of jejunal metastasis of pleomorphic lung cancer. Pleomorphic carcinoma of the lung is a rare pathology that accounts for 0.1-0.4% of nonsmall-cell lung cancer. The prognosis is poor. In the presence of gastrointestinal bleeding caused by small bowel metastases of pleomorphic lung cancer, surgery is the treatment of choice. Conclusions: Small bowel metastasis of pleomorphic lung cancer is rare. Surgical treatment is the treatment of choice. The authors highlight the importance of suspecting gastrointestinal metastases in patients with pleomorphic lung cancer in the presence of nonspecific digestive symptoms.
ABSTRACT
Anaplastic thyroid carcinoma (ATC) is a rare malignancy with a poor prognosis. It is characterized by abrupt development with local and distant metastases. Metastases are essentially present in the lung. Pancreatic metastasis is extremely rare. The authors report that, to their knowledge, this is the first reported case of a patient who developed metachronous pancreatic metastasis related to ATC. Case Presentation: A 65-year-old woman, with a history of thyroidectomy, 2 years prior, for an anaplastic thyroid tumor presented in his regular follow-up computed tomography scan a hypodense lesion of the head of the pancreas. Definite diagnosis of neoplasm was difficult following the computed tomography-guided fine-needle aspiration biopsy. The patient had a cephalic duodenopanceatectomy with an uneventful recovery. Histopathology concluded in a pancreatic metastasis of ATC metastasis. The patient had uneventful outcomes with a follow-up of 3 months without tumor recurrence. Conclusion: Pancreatic metastases of thyroid carcinomas are extremely rare, particularly for ATC. The diagnosis of metastases is based on a regular follow-up. The prognosis is poor despite curative surgery.
