[Anticyan--a new highly effective antidote in cyanide poisoning]. / Antitsian--novyi vysokoéffektivnyi antidot pri otravlenii tsianidami.

Anticyan is a highly effective antidote of cyanic acid and cyanide-containing compounds. It was created at the Institute of Pharmacology and Toxicology of AMS of Ukraine. Anticyan differs from other existing cyanide antidotes in that it possesses a tready methemoglobin-formation activity, has no hypotensive effect and is capable of direct stimulation of cyanide-inhibited tissue respiration.

[Experimental morphological study of the effect of liposomes in CCl4 poisoning]. / Eksperimental'no-morfologicheskoe izuchenie vliianiia liposom pri intoksikatsii CCl4.

The experiments on white mice have shown CCl4 to induce 24 hours after its injection focal changes in the liver, such as hepatocyte necrotization accompanied by lell organoid destruction, drastic reduction in glycogen content and increased fat content, as well as considerable decline in the activity of aerobic and anaerobic metabolic enzymes. Liposome administration attenuated the lytic effect of poison, promoting the integrity of subcellular hepatocyte structures. Distrophic changes in the latter led to increased glycogen content lower lipid level and intensified bioenergic processes.

[Thiol compounds in the combined therapy of prozerin poisonings]. / Tiolovye soedineniia v kombinirovannoi terapii otravlenii prozerinom.

The authors studied the protective action of dithiols (unithiol, dithiothreitol) and their combinations with atropine in proserine poisoning. With the use of the spatial-prospective plotting the antidote efficacy of dipyroxime, atropine, dithiothreitole, and their combinations was studied and compared. A new type of potentiation was discovered upon combined use of atropine, dipyroxime and dithiothreitol.