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Int J Antimicrob Agents ; 18(2): 193-6, 2001 Aug.
Article in English | MEDLINE | ID: mdl-11516945

ABSTRACT

Specimens from the nose and throat were collected from 28 long-term haemodialysed patients. Staphylococcus aureus strains were isolated from sixteen patients who been on haemodialysis for over 113 months. Cytokine levels, as well as full blood cell differential counts and cell surface antigens were determined in these patients. The serum concentration of TGF-beta was significantly higher in patients carrying Staphylococcus aureus. CD14 and HLA-DR molecule expression on monocytes, as well as NK cell percentage was significantly different in S. aureus carriers. Our preliminary results suggest that immune status imbalance in haemodialysed patients could be related to the high incidence of S. aureus nasal carriage and infections.


Subject(s)
Carrier State/microbiology , Immunocompromised Host , Nose/microbiology , Renal Dialysis , Staphylococcal Infections/microbiology , Staphylococcus aureus/isolation & purification , Adult , Carrier State/epidemiology , Carrier State/immunology , Cytokines/blood , Female , Humans , Leukocyte Count , Lymphocytes/immunology , Male , Middle Aged , Pharynx/microbiology , Staphylococcal Infections/epidemiology , Staphylococcal Infections/immunology
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