ABSTRACT
The authors analyze the parameters of total and local immunity in patients with acute and exacerbating chronic periodontitis. No essential changes in the mean values of blood characteristics were revealed, though T lymphocyte level was reduced in the acute period of the condition. Studies of the local immunity have revealed more significant shifts, particularly in the material from the involved tooth gingival groove, where both quantitative parameters and cellular functional activity were changed.
Subject(s)
Periodontitis/immunology , Acute Disease , B-Lymphocytes/immunology , Chronic Disease , Humans , Immunity, Cellular/immunology , Leukocyte Count , Mouth/immunology , Rosette Formation , T-Lymphocytes/immunologyABSTRACT
Presents data on functioning of the oral cavity local immunity organ, gingival groove. Analyzes a relationship between the counts and functional activities of the cells from the gingival groove and oral cavity washing, specific features of these cells in various conditions of the maxillodental segment.
Subject(s)
Gingiva/immunology , Immune System/immunology , Mouth Diseases/immunology , Tooth/immunology , Aged , Aged, 80 and over , Gingivitis/immunology , Humans , Immunity, Cellular , Middle Aged , Periodontitis/immunology , Pulpitis/immunologyABSTRACT
The authors have developed a complex of immunologic tests based on micromodifications of rapid methods of rosette formation and phagocytosis. The method requires the minimal amounts of cells and reagents, i.e. 0.03 ml of capillary blood from the finger is sufficient for the assessment of the general and local (round one tooth) immunity. Immunologic parameters of capillary blood, oral cavity washings, and material from the gingival groove were determined for the first time with the use of the above technique in normal subjects with sanitized oral cavity.