ABSTRACT
BACKGROUND: Atlanto-occipital transarticular screw fixation (AOTSF) has rarely been reported for fixation of the craniovertebral junction (CVJ). METHODS: A retrospective chart review of all pediatric patients (less than 18 years of age) with an attempt of AOTSF for fixation of traumatic CVJ instability was conducted. RESULTS: A total of 4 patients (2 boys and 2 girls; ages 2, 3, 5, and 8 years) who suffered from acute traumatic CVJ instability managed during 2007-2018 underwent an attempted AOTSF. In 2 patients, this method was technically successful. In the other 2 instances, we were not able to engage the screw into the occipital condyle. These were converted to standard occipital plate, rod, and screw fixation. All were placed in a halo subsequently for a minimum of 3 months. Three patients were fused at last follow-up (range, 17-48 months). One patient after successful AOTSF did not fuse. There were no surgical complications or revision procedures. CONCLUSIONS: AOTSF was feasible in half of pediatric patients suffering from traumatic CVJ instability. Therefore, intraoperative salvage options and strategies should be on hand readily. In the pediatric population, where bony anatomy may pose challenges to fixation, this technique may offer a viable first-line option in selected cases, despite the overall modest success rate.
Subject(s)
Atlanto-Occipital Joint/surgery , Bone Screws , Cervical Vertebrae/surgery , Joint Instability/surgery , Occipital Bone/surgery , Spinal Fusion/methods , Adolescent , Atlanto-Occipital Joint/diagnostic imaging , Cervical Vertebrae/diagnostic imaging , Child , Child, Preschool , Female , Follow-Up Studies , Humans , Internal Fixators , Joint Instability/diagnostic imaging , Male , Occipital Bone/diagnostic imaging , Retrospective Studies , Spinal Fusion/instrumentationSubject(s)
Amputation, Surgical/methods , Aspergillosis/drug therapy , Bacteremia/surgery , Burns/diagnosis , Burns/surgery , Amputation, Surgical/rehabilitation , Aspergillosis/complications , Aspergillosis/diagnosis , Bacteremia/etiology , Bacteremia/physiopathology , Burn Units , Burns/complications , Burns/drug therapy , Female , Femur/surgery , Follow-Up Studies , Humans , Infant , Injury Severity Score , Severity of Illness Index , Treatment Outcome , Wound Infection/diagnosis , Wound Infection/microbiology , Wound Infection/surgeryABSTRACT
This case-series describes the 6 human infections with Onchocerca lupi, a parasite known to infect cats and dogs, that have been identified in the United States since 2013. Unlike cases reported outside the country, the American patients have not had subconjunctival nodules but have manifested more invasive disease (eg, spinal, orbital, and subdermal nodules). Diagnosis remains challenging in the absence of a serologic test. Treatment should be guided by what is done for Onchocerca volvulus as there are no data for O. lupi. Available evidence suggests that there may be transmission in southwestern United States, but the risk of transmission to humans is not known. Research is needed to better define the burden of disease in the United States and develop appropriately-targeted prevention strategies.
Subject(s)
Communicable Diseases, Emerging , Dog Diseases/epidemiology , Onchocerca/isolation & purification , Onchocerciasis , Zoonoses , Adolescent , Animals , Cats , Child , Child, Preschool , Communicable Diseases, Emerging/diagnosis , Communicable Diseases, Emerging/epidemiology , Communicable Diseases, Emerging/parasitology , Communicable Diseases, Emerging/transmission , Cost of Illness , Dog Diseases/diagnosis , Dog Diseases/parasitology , Dogs , Female , Humans , Infant , Male , Middle Aged , Onchocerca/genetics , Onchocerciasis/diagnosis , Onchocerciasis/parasitology , Onchocerciasis/transmission , Onchocerciasis/veterinary , Southwestern United States/epidemiology , United States/epidemiology , Zoonoses/diagnosis , Zoonoses/epidemiology , Zoonoses/parasitology , Zoonoses/transmissionABSTRACT
A 22-month-old girl presented with neck pain and stiffness and magnetic resonance imaging showed an extradural mass extending from C2 through the C4 level with moderate to severe compression of the cord. A left unilateral C2-C4 laminectomy was performed revealing an extradural rubbery tumor; a small biopsy was obtained. Examination of stained tissue revealed the presence of a parasitic worm that was identified as a gravid female Onchocerca lupi. A magnetic resonance imaging at 7 weeks follow-up showed a significantly decreased size of the enhancing lesion and the patient's symptoms gradually resolved. This is the first report of zoonotic O. lupi in the United States. The parasite has been reported in dogs and cats in the western United States, and from people in four cases reported from Europe. A great deal more needs to be learned, including full host range and geographic distribution, before we fully understand O. lupi infections in animals and man.