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1.
Clin Psychopharmacol Neurosci ; 22(1): 87-94, 2024 Feb 29.
Article in English | MEDLINE | ID: mdl-38247415

ABSTRACT

Objective: : Diagnosis and assessment of depression rely on scoring systems based on questionnaires, either self-reported by patients or administered by clinicians, and observation of patient facial expressions during the interviews plays a crucial role in making impressions in clinical settings. Deep learning driven approaches can assist clinicians in the course of diagnosis of depression by recognizing subtle facial expressions and emotions in depression patients. Methods: : Seventeen simulated patients who acted as depressed patients participated in this study. A trained psychiatrist structurally interviewed each participant with moderate depression in accordance with a prepared scenario and without depressive features. Interviews were video-recorded, and a facial emotion recognition algorithm was used to classify emotions of each frame. Results: : Among seven emotions (anger, disgust, fear, happiness, neutral, sadness, and surprise), sadness was expressed in a higher proportion on average in the depression-simulated group compared to the normal group. Neutral and fear were expressed in higher proportions on average in the normal group compared to the normal group. The overall distribution of emotions between the two groups was significantly different (p < 0.001). Variance in emotion was significantly less in the depression-simulated group (p < 0.05). Conclusion: : This study suggests a novel and practical approach to understand the emotional expression of depression patients based on deep learning techniques. Further research would allow us to obtain more perspectives on the emotional profiles of clinical patients, potentially providing helpful insights in making diagnosis of depression patients.

2.
Front Psychiatry ; 14: 1256571, 2023.
Article in English | MEDLINE | ID: mdl-38239906

ABSTRACT

Background: A psychiatric interview is one of the important procedures in diagnosing psychiatric disorders. Through this interview, psychiatrists listen to the patient's medical history and major complaints, check their emotional state, and obtain clues for clinical diagnosis. Although there have been attempts to diagnose a specific mental disorder from a short doctor-patient conversation, there has been no attempt to classify the patient's emotional state based on the text scripts from a formal interview of more than 30 min and use it to diagnose depression. This study aimed to utilize the existing machine learning algorithm in diagnosing depression using the transcripts of one-on-one interviews between psychiatrists and depressed patients. Methods: Seventy-seven clinical patients [with depression (n = 60); without depression (n = 17)] with a prior psychiatric diagnosis history participated in this study. The study was conducted with 24 male and 53 female subjects with the mean age of 33.8 (± 3.0). Psychiatrists conducted a conversational interview with each patient that lasted at least 30 min. All interviews with the subjects between August 2021 and November 2022 were recorded and transcribed into text scripts, and a text emotion recognition module was used to indicate the subject's representative emotions of each sentence. A machine learning algorithm discriminates patients with depression and those without depression based on text scripts. Results: A machine learning model classified text scripts from depressive patients with non-depressive ones with an acceptable accuracy rate (AUC of 0.85). The distribution of emotions (surprise, fear, anger, love, sadness, disgust, neutral, and happiness) was significantly different between patients with depression and those without depression (p < 0.001), and the most contributing emotion in classifying the two groups was disgust (p < 0.001). Conclusion: This is a qualitative and retrospective study to develop a tool to detect depression against patients without depression based on the text scripts of psychiatric interview, suggesting a novel and practical approach to understand the emotional characteristics of depression patients and to use them to detect the diagnosis of depression based on machine learning methods. This model could assist psychiatrists in clinical settings who conduct routine conversations with patients using text transcripts of the interviews.

3.
Appl Radiat Isot ; 67(7-8): 1234-8, 2009.
Article in English | MEDLINE | ID: mdl-19328704

ABSTRACT

A micro-battery powered by tritium is being developed to utilize tritium produced from the Wolsong Tritium Removal Facility. The 3D p-n junction device has been designed and fabricated for energy conversion. Titanium tritide is adopted to increase tritium density and safety. Sub micron films or nano-powders of titanium tritide is applied on silicon semiconductor device to reduce the self absorption of beta rays. Until now protium has been used instead of tritium for safety. Hydrogen was absorbed up to atomic ratio of approximately 1.3 and approximately 1.7 in titanium powders and films, respectively.


Subject(s)
Electric Power Supplies , Tritium , Equipment Design , Miniaturization , Nuclear Energy , Titanium
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