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1.
Pharmacopsychiatry ; 46(4): 137-46, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23364873

ABSTRACT

Given the shortage of studies on parental perceived benefits of OROS-methylphenidate treatment in Asian populations, we assessed parental response to OROS-methylphenidate treatment of Korean children with attention-deficit/hyperactivity disorder (ADHD), in relation to children's academic performance and behavioral symptoms as well as parental rearing stress and depressive symptoms.We enrolled 132 medication-naïve children with ADHD into a multicenter, open-label, 12-week trial of OROS-MPH. The outcome measures were the ADHD rating scale-IV (ADHD-RS), the comprehensive attention test and academic performance rating scale, and the clinical global impression (CGI)-severity/improvement instrument (for the children) and Beck depression inventory and parenting stress index (for their parents).We found parent-perceived improvements in children's ADHD-related behavioral symptoms and academic function and their parents' depressive symptoms and parenting stress. Investigator-rated ADHD symptoms and subjects' neuropsychological function were also improved (p<0.001).Parents of Korean children with ADHD perceive that OROS-methylphenidate treatment improves their children's academic function and behavior as well as their own child-rearing stress and emotional state. These findings must be interpreted with caution, due to a non-comparative open-label trial.


Subject(s)
Attention Deficit Disorder with Hyperactivity/drug therapy , Central Nervous System Stimulants/therapeutic use , Methylphenidate/therapeutic use , Parents/psychology , Adult , Asian People , Attention/physiology , Attention Deficit Disorder with Hyperactivity/psychology , Caregivers/psychology , Central Nervous System Stimulants/administration & dosage , Central Nervous System Stimulants/adverse effects , Child , Depression/psychology , Diagnostic and Statistical Manual of Mental Disorders , Educational Status , Female , Humans , Male , Methylphenidate/administration & dosage , Methylphenidate/adverse effects , Middle Aged , Neuropsychological Tests , Parenting/psychology , Republic of Korea , Stress, Psychological/psychology , Treatment Outcome
2.
J Hand Surg Eur Vol ; 38(7): 719-26, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23303834

ABSTRACT

We retrospectively studied the radiological and clinical results of a simple hemiresection arthroplasty, a modification of previous oblique distal ulnar resections, in 62 patients with rheumatoid arthritis (68 wrists) over a mean follow-up of 103 (range 60-173) months. Fourteen wrists (20%) became fused at the radiocarpal joint and 28 wrists fused (41%) at the midcarpal joints during follow-up. Severe ulnar translocation of the carpus was observed in two wrists (3%), radio-ulnar convergence in five wrists (7%), as well as a significant decrease of carpal height ratio, without any radiological findings of stylocarpal impingement. Improvements in forearm pronation and supination, and reduction in pain were maintained at the last follow-up. Grip strength was not significantly improved. The Jebsen-Taylor hand function test showed improvements in writing, card turning, and simulated feeding. Fifty-two patients (58 wrists, 85%) were satisfied with the results at the last follow-up. Simple hemiresection arthroplasty showed good long-term results with few complications.


Subject(s)
Arthritis, Rheumatoid/surgery , Arthroplasty/methods , Wrist Joint/surgery , Adult , Aged , Arthritis, Rheumatoid/diagnostic imaging , Arthritis, Rheumatoid/physiopathology , Female , Follow-Up Studies , Hand Strength , Humans , Male , Middle Aged , Radiography , Range of Motion, Articular/physiology , Retrospective Studies , Treatment Outcome , Wrist Joint/diagnostic imaging , Wrist Joint/physiopathology
4.
J Hand Surg Eur Vol ; 35(4): 279-82, 2010 May.
Article in English | MEDLINE | ID: mdl-19687080

ABSTRACT

We evaluated the clinical outcome of tendon reconstruction using tendon graft or tendon transfer and the parameters related to clinical outcome in 51 wrists of 46 patients with rheumatoid arthritis with finger extensor tendon ruptures. At a mean follow-up of 5.6 years, the mean metacarpophalangeal (MP) joint extension lag was 8 degrees (range, 0-45) and the mean visual analogue satisfaction scale was 74 (range, 10-100). Clinical outcome did not differ significantly between tendon grafting and tendon transfer. The MP joint extension lag correlated with the patient's satisfaction score, but the pulp-to-palm distance did not correlate with patient satisfaction. We conclude that both tendon grafting and tendon transfer are reliable reconstruction methods for ruptured finger extensor tendons in rheumatoid hands.


Subject(s)
Arthritis, Rheumatoid/complications , Fingers , Tendon Injuries/surgery , Tendon Transfer , Tendons/transplantation , Adult , Arthritis, Rheumatoid/physiopathology , Arthritis, Rheumatoid/surgery , Female , Follow-Up Studies , Humans , Male , Middle Aged , Patient Satisfaction , Range of Motion, Articular , Recovery of Function , Retrospective Studies , Rupture , Tendon Injuries/etiology , Tendon Injuries/physiopathology , Treatment Outcome , Young Adult
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