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1.
Endocr Pract ; 30(2): 122-127, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37952581

ABSTRACT

OBJECTIVE: People with diabetes mellitus, particularly those with limited access to longitudinal care, frequently present to the emergency department (ED). Continuous glucose monitoring (CGM) has been shown to improve outcomes in ambulatory settings, so we hypothesized that it would be beneficial if initiated upon ED discharge. METHODS: We randomized adults with diabetes who were seen in the ED for hypo- or hyperglycemia to either 14 days of flash CGM or care coordination alone. All participants were scheduled to follow up in our diabetes specialty clinic. Outcomes included clinic attendance, the 3-month change in hemoglobin A1c, and repeat ED utilization. RESULTS: We recruited 30 participants, including 13 with newly diagnosed diabetes. All but one (97%) had type 2 diabetes. We found no significant difference between the CGM (n = 16) and control (n = 14) groups in terms of clinic attendance (75 vs 64%, P = .61) or repeat ED utilization (31 vs 50%, P = .35), although our power was low. The absolute reduction in A1c was greater in the CGM group (5.2 vs 2.4%, P = .08). Among newly diagnosed participants for whom we had data, 7 out of 7 in the CGM group had a follow-up A1c under 7% compared to 1 out of 3 in the control group (P = .03). Over 90% of patients and providers found the CGM useful. CONCLUSIONS: Our data demonstrate the feasibility of starting CGM in the ED, a valuable setting for engaging difficult-to-reach patients. Our pilot study was limited by its small sample size, however, as recruitment in the ED can be challenging.


Subject(s)
Diabetes Mellitus, Type 1 , Diabetes Mellitus, Type 2 , Hypoglycemia , Adult , Humans , Blood Glucose , Glycated Hemoglobin , Hypoglycemic Agents , Hypoglycemia/diagnosis , Pilot Projects , Diabetes Mellitus, Type 2/therapy , Blood Glucose Self-Monitoring , Continuous Glucose Monitoring , Patient Discharge
2.
AEM Educ Train ; 7(6): e10918, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38037628

ABSTRACT

Background: More than 90% of pediatric patients presenting to emergency departments (EDs) in the United States are evaluated and treated in community-based EDs. Recent evidence suggests that mortality outcomes may be worse for critically ill pediatric patients treated at community EDs. The disparate mortality outcomes may be due to inconsistency in pediatric-specific education provided to emergency medicine (EM) trainees during residency training. There are few studies surveying recently graduated EM physicians assessing perceived gaps in the pediatric emergency medicine (PEM) education they received during residency. Methods: This was a prospective, survey-based, descriptive cohort study of EM residency graduates from 10 institutions across the United States who were <5 years out from residency training. Deidentified surveys were distributed via email. Results: A total of 222 responses were obtained from 570 eligible participants (39.1%). Non-ED pediatric rotations during residency training included pediatric intensive care (60%), pediatric anesthesia (32.4%), neonatal intensive care unit (26.1%), and pediatric wards (17.1%). A large percentage (42.8%) of respondents felt uncomfortable managing neonates and performing tube thoracostomy on pediatric patients (56.3%). The EM graduate's satisfaction with pediatric simulation-based training during residency was positively associated with comfort caring for neonates and infants (p < 0.0070 and p < 0.0002) and performing endotracheal intubation (p < 0.0027), lumbar puncture (p < 0.0004), and Pediatric Advanced Life Support resuscitation (p < 0.0001). Conclusions/discussion: This survey-based cohort study found considerable variation in pediatric-specific experiences during EM residency training and in perceived comfort managing pediatric patients. In general, participants were more comfortable managing older children. This study suggests that the greatest perceived knowledge gaps in PEM were neonatal medicine/resuscitation and pediatric cardiac arrest. Future research will continue to address larger cohorts, representative of the PEM education provided to EM physicians in the United States to promote future educational initiatives.

3.
J Environ Manage ; 346: 118997, 2023 Nov 15.
Article in English | MEDLINE | ID: mdl-37769367

ABSTRACT

Various tools and techniques are used by environmental managers and planning agencies to make land use decisions that balance different and often competing goals. Multiple goals, or objectives, are generally challenging to address because there is likely no single optimal solution, but rather a range of possible Pareto (or tradeoff) solutions. Considerable attention has focused on software and approaches that rely on heuristic methods to generate solutions for land use planning problems with multiple objectives. While fast and accessible, there remain uncertainties about the quality of solutions obtained by these heuristic methods and whether they are indeed meeting the needs of environmental managers. This paper explores forest treatment planning for wildfire risk mitigation seeking to balance multiple objectives when the spatial pattern of treatment is restricted. Solution quality of one widely employed forest planning tool is evaluated (using measures of completeness, inferiority, and maximum gap) under a range of geographic settings and problem sizes. The findings indicate that obtained solutions are suboptimal, and fail to represent the full spectrum of tradeoffs possible.

4.
West J Emerg Med ; 24(4): 732-736, 2023 Jul 12.
Article in English | MEDLINE | ID: mdl-37527387

ABSTRACT

INTRODUCTION: In the Program Requirements for Graduate Medical Education in Emergency Medicine, the Accreditation Council for Graduate Medical Education requires frequent and routine feedback. It is a common challenge for program leadership to obtain adequate and effective summative evaluations. METHODS: This is a retrospective, case-crossover, interventional study conducted in an academic medical center. This study occurred over a two-year period, with an intervention between years one and two. Throughout year two of the study, faculty incentive compensation was linked to completion of end-of-shift evaluations. We compared pre- an post-implementation data using paired sample t-tests with the significance level P < .05 applied. RESULTS: After implementation of the incentive metric there was an increase in the number of total evaluations by 42% (P = .001). The mean number of evaluations submitted by each faculty per shift increased from 0.45 to 0.86 (SD 0.56, P < .001). Overall, 32 of the 38 faculty members (84.2%) had an increase in the number of evaluations submitted per shift during the intervention period with an average increase of 0.5 evaluations per shift (range 0.01-1.54). CONCLUSION: Incentivizing faculty to submit resident evaluations through use of bonus compensation increased the number of evaluations at our institution. This information may be applied by other programs to increase resident evaluations.


Subject(s)
Internship and Residency , Humans , Retrospective Studies , Clinical Competence , Education, Medical, Graduate , Faculty, Medical
5.
BJOG ; 130(1): 15-23, 2023 01.
Article in English | MEDLINE | ID: mdl-36047598

ABSTRACT

OBJECTIVE: To test the equivalence of two doses of intravenous iron (ferric carboxymaltose) in pregnancy. DESIGN: Parallel, two-arm equivalence randomised controlled trial with an equivalence margin of 5%. SETTING: Single centre in Australia. POPULATION: 278 pregnant women with iron deficiency. METHODS: Participants received either 500 mg (n = 152) or 1000 mg (n = 126) of intravenous ferric carboxymaltose in the second or third trimester. MAIN OUTCOME MEASURES: The proportion of participants requiring additional intravenous iron (500 mg) to achieve and maintain ferritin >30 microg/L (diagnostic threshold for iron deficiency) at 4 weeks post-infusion, and at 6 weeks, and 3-, 6- and 12-months postpartum. Secondary endpoints included repeat infusion rate, iron status, birth and safety outcomes. RESULTS: The two doses were not equivalent within a 5% margin at any time point. At 4 weeks post infusion, 26/73 (36%) participants required a repeat infusion in the 500-mg group compared with 5/67 (8%) in the 1000-mg group: difference in proportions, 0.283 (95% confidence interval [CI] 0.177-0.389). Overall, participants in the 500-mg arm received twice the repeat infusion rate (0.81 [SD = 0.824] versus 0.40 [SD = 0.69], rate ratio 2.05, 95% CI 1.45-2.91). CONCLUSIONS: Administration of 1000 mg ferric carboxymaltose in pregnancy maintains iron stores and reduces the need for repeat infusions. A 500- mg dose requires ongoing monitoring to ensure adequate iron stores are reached and sustained.


Subject(s)
Anemia, Iron-Deficiency , Iron Deficiencies , Female , Humans , Pregnancy , Iron , Anemia, Iron-Deficiency/drug therapy , Maltose/therapeutic use , Ferric Compounds/therapeutic use , Administration, Intravenous
6.
J Am Coll Emerg Physicians Open ; 3(1): e12643, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35079732

ABSTRACT

OBJECTIVES: Investigations of the impact of residents on emergency department (ED) timeliness of care typically focus only on global ED flow metrics. We sought to describe the association between resident complement/supervisory ratios and timeliness of ED care of a specific time-sensitive condition, acute stroke. METHODS: We matched ED stroke patient arrivals at 1 academic stroke center against resident and attending staffing and constructed a Cox proportional hazards model of door-to-activation (DTA) time (ie, ED arrival ["door"] to stroke team activation). We considered multiple predictors, including calculated ratios of residents supervised by each attending physician. RESULTS: Among 462 stroke activation patients in 2014-2015, DTA ranged from 1 to 217 minutes, 72% within 15 minutes. The median number of emergency and off-service residents supervised per attending were 1.7 (interquartile range [IQR], 1.3-2.3) and 0.7 (IQR, 0-1), respectively. A 1-resident increase in off-service residents was associated with a 24% decrease (hazard ratio [HR], 0.76; 95% confidence interval [CI], 0.64-0.90) in the probability of stroke team activation at any given time. An independent 1-resident increase in the number of emergency residents was associated with a 13% increase (HR, 1.13; 95% CI, 1.01-1.25) in timely activation. CONCLUSION: Timeliness of care for acute stroke may be impacted by how academic EDs configure the complement and supervisory structures of residents. Higher supervisory demands imposed by increasing the proportion of rotating off-service residents may be associated with slower stroke recognition and DTA times, but this effect may be offset when more emergency residents are present.

7.
Clin Pract Cases Emerg Med ; 5(2): 273-274, 2021 May.
Article in English | MEDLINE | ID: mdl-34437027

ABSTRACT

CASE PRESENTATION: A 26-year-old male presented to our emergency department for six days of right-sided facial myasthenia and parasthesias following a dental procedure using anesthetic nerve blocks. DISCUSSION: Iatrogenic cranial nerve VII neuropraxia, a peripheral nerve injury, is an uncommon complication of alveolar nerve blocks with few documented cases specifically due to dental anesthesia. Treatment usually involves use of oral corticosteroid and/or antiviral medications along with close follow-up in clinic with a neurologist and/or otolaryngologist.

8.
Nanoscale ; 9(29): 10161-10166, 2017 Jul 27.
Article in English | MEDLINE | ID: mdl-28702585

ABSTRACT

Perfluorocarbon (PFC) emulsions are capable of absorbing large quantities of oxygen. They are widely used as blood alternates for quick oxygenation of tissues. However, they are unsuitable for applications where sustained oxygen supply is desired over an extended period of time. Here, we have designed a new PFC oxygen delivery system that combines perfluorodecalin with graphene oxide (GO), where GO acts both as an emulsifier and a stabilizing agent. The resulting emulsions (PFC@GO) release oxygen at least one order of magnitude slower than emulsions prepared with other common surfactants. The release rate can be controlled by varying the thickness of the GO layer. Controlled release of oxygen make these emulsions excellent oxygen carriers for applications where sustained oxygen delivery is required e.g. in tissue regeneration and vascular wound healing.


Subject(s)
Drug Delivery Systems , Emulsions , Fluorocarbons , Graphite , Oxygen/administration & dosage , Proof of Concept Study
9.
BJPsych Bull ; 41(1): 21-29, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28184313

ABSTRACT

This review considers juvenile delinquency and justice from an international perspective. Youth crime is a growing concern. Many young offenders are also victims with complex needs, leading to a public health approach that requires a balance of welfare and justice models. However, around the world there are variable and inadequate legal frameworks and a lack of a specialist workforce. The UK and other high-income countries worldwide have established forensic child and adolescent psychiatry, a multifaceted discipline incorporating legal, psychiatric and developmental fields. Its adoption of an evidence-based therapeutic intervention philosophy has been associated with greater reductions in recidivism compared with punitive approaches prevalent in some countries worldwide, and it is therefore a superior approach to dealing with the problem of juvenile delinquency.

11.
Disabil Rehabil ; 27(13): 769-79, 2005 Jul 08.
Article in English | MEDLINE | ID: mdl-16096229

ABSTRACT

PURPOSE: Persons with visual impairments or blindness can face significant restrictions to their efficient travel, especially when attempting transit transfers and using a large, multi-modal terminal. Little is known about what makes some tasks much harder than others. This paper presents an approach to empirically measure the difficulty of a variety of transit tasks. METHOD: An experiment was conducted at an urban transit terminal, with three other transit modes nearby. Thirty persons with visual impairments attempted to make five simulated transfers between these modes. Errors and time to complete these tasks were collected in order to quantify the nature of various barriers to efficient travel for this group. In total, 20 locations were visited. Completion times were compared to a sighted traveler to determine a measure of the time penalty, or 'relative access measure.' RESULTS: Two basic findings are reported. Empirical data showed that different types of transit tasks and locations had a wide range of difficulty and inherent time penalties. Some tasks like crossing a difficult street, finding unmarked track doors, and finding inconsistently placed amenities were quite time consuming and sometimes impossible to accomplish. Other tasks, like walking to a street corner and crossing a simpler street, had much lower penalties and could be completed with ease. CONCLUSIONS: The placement of additional cues, those of identity and direction, provided with auditory signage, were able to eliminate much of the uncertainty and time restrictions associates with transit use and navigation for persons with visual impairments.


Subject(s)
Architectural Accessibility , Blindness/physiopathology , Disabled Persons/rehabilitation , Efficiency , Adult , Aged , Blindness/rehabilitation , Female , Humans , Male , Middle Aged , Orientation , Task Performance and Analysis
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