[The postamputation syndrome in rats and its neurochemical characteristics]. / Postamputatsionnyi sindrom u krys i ego neirokhimicheskie kharakteristiki.

Noradrenergic and GABA-ergic systems were correlated and dominated in the processes of spinal cord segmentary apparatus superactivity compensation. An increase in c-GMP content in the spinal cord suggests an intensification of the activation mechanism. An increase in the c-AMP content may suggest an inhibition of the compensatory intensification of noradrenergic or GABA-ergic mechanisms.

[Characteristics of creatine kinase isoenzyme spectrum in the blood of rats in aging and acute alcoholic intoxication]. / Kharakteristika izofermentnogo spektra kreatinkinazy v syvorotke krovi krys pri starenii i ostroi alkogol'noi intoksikatsii.

The study of creatine kinase (CK) activity in biological liquids of rats of different age has shown that CK blood activity is decreased in aged rats. Acute alcohol intoxication leads to significant increase of CK blood activity.

[Dynamics of activity of creatine kinase and its isoenzymes in the serum of patients with alcoholism]. / Dinamika aktivnosti kreatinkinazy i ee izofermentov v syvorotke krovi bol'nykh alkogolizmom.

Activity of creatine kinase (CK) and its isoenzymes was studied in blood serum of 32 patients with alcohol abstinent syndrome of various severity as well as in persons with long-term remission (from 1 to 14 years) as compared with the enzymatic activity in healthy volunteers. The severity of alcohol abstinent syndrome correlated with an increase in the total enzyme activity in blood, where content of the all three CK isoenzymes (MM, MB and BB), especially of BB-CK, was elevated. Content of MB and BB isozymes was increased in blood of patients with long-term remission, while activity of each of the isozyme constituted up to 20-30% of total CK activity, which was by one decimal order higher as compared with control values. Importance of the alterations observed in activity of creatine kinase and its isoenzymes for diagnosis of alcoholism, especially under conditions of alcohol abuse and long-term alcohol abstinence, is discussed.

[The determination of the creatine kinase content of the blood in patients with nonspecific ulcerative colitis as a supplementary diagnostic test]. / Opredelenie soderzhaniia kreatinkinazy v krovi bol'nykh nespetsificheskim iazvennym kolitom kak dopolnitel'nyi diagnosticheskii test.

A direct relationship between the disease course and the total activity of creatine kinase in the blood serum was established in patients with nonspecific ulcerous colitis. A colorimetric method of measuring creatine kinase activity was employed. The creatine kinase test can be used as an additional diagnostic and prognostic indicator of the course of nonspecific ulcerous colitis.