ABSTRACT
High fat diet containing 50% fat was given to 28 Chinese healthy volunteers for 3 days. Their mean age was 28.04 years with SD 5.53. Blood glucose, cholesterol, triglyceride (TG) and venous occlusion test (VOT) were determined before and after diet. Tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI) were determined before and after VOT. After high-fat diet, blood glucose and cholesterol increased significantly (p = 0.031, 0.049 respectively), but other parameters did not. TPA increased significantly after VOT either before or after high-fat diet, but such increment was significantly less after high-fat diet (P < 0.05). In conclusion, the immediate effect of short-term high-fat diet included increased plasma levels of glucose and cholesterol, and impaired fibrinolytic response in stress condition.
Subject(s)
Dietary Fats/pharmacology , Fibrinolysis/drug effects , Adult , Blood Glucose/analysis , China , Constriction , Feeding Behavior , Female , Humans , Male , Plasminogen Activator Inhibitor 1/analysis , Thromboembolism/ethnology , Tissue Plasminogen Activator/analysis , Triglycerides/blood , VeinsABSTRACT
Blood glucose, cholesterol and triglyceride levels were determined and the venous occlusion test (VOT) was administered to 15 vegetarians (mean age 46.2 years, SD 15.1) and 20 non-vegetarians (mean age 38.3 years, SD 8.3). The tissue plasminogen activator (tPA), plasminogen activator inhibitor (PAI) and euglobulin lysis time (ELT) were measured before and after VOT. The means of all the parameters were not significantly different between vegetarians and non-vegetarians. TPA increased after VOT in both the vegetarians and the non-vegetarians, but the changing amplitudes of tPA, PAI and ELT induced by VOT were not significantly different in either group. This study evidenced no significant difference in the changes of fibrinolytic activity between vegetarians and non-vegetarians.
Subject(s)
Diet, Vegetarian , Fibrinolysis , Adult , Aged , Blood Coagulation Tests , Blood Glucose/analysis , Female , Humans , Lipids/blood , Male , Middle Aged , Plasminogen Activators/analysis , Tissue Plasminogen Activator/analysisSubject(s)
Dietetics/legislation & jurisprudence , Licensure , Societies , Dietetics/trends , Humans , TaiwanSubject(s)
Blood Glucose/metabolism , Fabaceae , Plants, Medicinal , Diabetes Mellitus, Type 2/blood , Diet, Diabetic , Female , Humans , Male , Middle AgedABSTRACT
The effect of oral iron supplementation on blood Fe levels and physical growth in 119 rural Indonesian school children was assessed in this double-blind study. The children were classified into anemic and normal groups according to their initial hemoglobin and transferrin saturation levels and were randomly assigned to either Fe or placebo treatment for 12 wk. Hematological, anthropometric, and morbidity data were collected before and after the treatment period. Before treatment, anemic subjects were smaller and had higher morbidity than normal subjects. Treatment with 10 mg ferrous sulfate.kg-1.d-1 for 12 wk resulted in a significant improvement in anemic subjects' hematological status, growth velocity, and level or morbidity.
