Subject(s)
Adjustment Disorders/diagnosis , Depression/diagnosis , Depressive Disorder/diagnosis , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle AgedABSTRACT
This work is based upon the study of 472 cases from author's private practice. We considered the three following starting points: a) Catecholaminic hypothesis of depressive disorders such as formulated by late Prof. E. Fischer. b) Biochemical analysis of neuro transmitters according to H. Spatz and Mattock to study clinical and laboratory correlation and guide therapy. c) Biological psychiatry's practice and experience in our empirical definition of a final metabolic response to the patients situation. We would like to stress the following conclusions resulting from this investigation: first, the efficacy without unwanted side effects of the formula described as treatment B in the special paragraph; second, a stronger response to tricyclics or Maois when the formula is also administered; third, the confirmation of previous reports pointing out low PEA urinary elimination in those patients with clinical diagnoses different from endogenous depression.
Subject(s)
Catecholamines/urine , Depressive Disorder/metabolism , Neurotransmitter Agents/metabolism , Adjustment Disorders/drug therapy , Adolescent , Adult , Aged , Aniline Compounds/therapeutic use , Antidepressive Agents/therapeutic use , Child , Depressive Disorder/drug therapy , Depressive Disorder/urine , Epoxy Compounds/therapeutic use , Female , Humans , Imipramine/therapeutic use , Male , Middle Aged , Monoamine Oxidase Inhibitors/therapeutic use , Mood Disorders/drug therapy , Neurotic Disorders/drug therapyABSTRACT
This work is based upon the study of 472 cases from authors private practice. We considered the three following starting points: a) Catecholaminic hypothesis of depressive disorders such as formulated by late Prof. E. Fischer. b) Biochemical analysis of neuro transmitters according to H. Spatz and Mattock to study clinical and laboratory correlation and guide therapy. c) Biological psychiatrys practice and experience in our empirical definition of a final metabolic response to the patients situation. We would like to stress the following conclusions resulting from this investigation: first, the efficacy without unwanted side effects of the formula described as treatment B in the special paragraph; second, a stronger response to tricyclics or Maois when the formula is also administered; third, the confirmation of previous reports pointing out low PEA urinary elimination in those patients with clinical diagnoses different from endogenous depression.
