Otro gran imitador..., con desenlace fatal / Another great wannabe..., with fatal outcome

No disponible

Análisis de la calidad de vida en pacientes con insuficiencia cardíaca mediante el cuestionario genérico SF-36 / Analysis of quality of life using the generic SF-36 questionnaire in patients with heart failure

Objetivo. La insuficiencia cardíaca es una de las principales enfermedades crónicas que afectan a la calidad de vida relacionada con la salud. El objetivo del presente estudio ha sido evaluar la calidad de vida en pacientes con clase funcional i - iii de la New York Heart Association mediante el cuestionario SF-36 usando una cohorte de supervivientes del Grupo de Estudio EPICOUR y compararlo con la calidad de vida de la población general española para el mismo sexo y grupo de edad. Material y métodos. Se diseñó un estudio de cohorte, observacional y prospectivo con los supervivientes del Grupo de Estudio EPICOUR a los que se les realizó control clínico-evolutivo y cuestionario SF-36. Resultados. Se estudió la calidad de vida en 50 pacientes (60% hombres). La edad media de los hombres fue de 64,8 años y de las mujeres de 68,3. Al analizar el SF-36 se observó que los resultados fueron más bajos en la esfera física que en la esfera mental. La calidad de vida empeoraba a medida que aumentaba la clase funcional. Al comparar los pacientes con la población general para el mismo sexo y edad, los pacientes con insuficiencia cardíaca mostraron puntuación inferior en todas las escalas (diferencias significativas en función física, dolor corporal, vitalidad y función social para los hombres y función física y rol emocional para las mujeres). Conclusiones. La insuficiencia cardíaca provoca un impacto negativo en la calidad de vida, tanto en la función física como en la función psicosocial, agravándose el deterioro con el incremento de la clase funcional(AU)

Objective: Heart failure is one of the major chronic diseases that affect health related quality of life. The objective of this study was to evaluate the quality of life in patients with New York Heart Association functional class i-iii using the SF-36 on a cohort of survivors of the EPICOUR Study Group and compare the quality of life with the general Spanish population of the same sex and age group. Material and methods: A cohort study, observational, and prospective study was conducted on survivors of the EPICOUR Study Group, on whom a clinical-progression-outcome review was performed along with the SF-36. Results: The quality of life was studied in 50 patients (60% male). The average age of men was 64.8 years and women 68.3. When analyzing the SF-36, it was observed that the results were lower in the physical dimensions than in the mental dimensions. The quality of life worsened with increasing functional class (statistically significant differences for scales of physical functioning, social functioning and borderline significance in mental health scale). When comparing patients with the general population of the same age and sex, patients with heart failure showed lower scores on all scales (significant differences in physical functioning, body pain, vitality, and social role for men, and physical function and emotional role for women). Conclusions: Heart failure causes a negative impact on quality of life, physical functioning, as well as psychosocial function, with the impairment becoming worse with increased functional class (AU)

[Analysis of quality of life using the generic SF-36 questionnaire in patients with heart failure]. / Análisis de la calidad de vida en pacientes con insuficiencia cardíaca mediante el cuestionario genérico SF-36.

OBJECTIVE: Heart failure is one of the major chronic diseases that affect health related quality of life. The objective of this study was to evaluate the quality of life in patients with New York Heart Association functional class I-III using the SF-36 on a cohort of survivors of the EPICOUR Study Group and compare the quality of life with the general Spanish population of the same sex and age group. MATERIAL AND METHODS: A cohort study, observational, and prospective study was conducted on survivors of the EPICOUR Study Group, on whom a clinical-progression-outcome review was performed along with the SF-36. RESULTS: The quality of life was studied in 50 patients (60% male). The average age of men was 64.8 years and women 68.3. When analyzing the SF-36, it was observed that the results were lower in the physical dimensions than in the mental dimensions. The quality of life worsened with increasing functional class (statistically significant differences for scales of physical functioning, social functioning and borderline significance in mental health scale). When comparing patients with the general population of the same age and sex, patients with heart failure showed lower scores on all scales (significant differences in physical functioning, body pain, vitality, and social role for men, and physical function and emotional role for women). CONCLUSIONS: Heart failure causes a negative impact on quality of life, physical functioning, as well as psychosocial function, with the impairment becoming worse with increased functional class.

[Hyponutrition prevalence among patients with digestive neoplasm before surgery]. / Prevalencia de desnutrición en pacientes con neoplasia digestiva previa cirugía.

OBJECTIVE: To analyze the prevalence and degree of hyponutrition among patients with resectable digestive neoplasm that will be submitted to surgery. MATERIAL AND METHODS: Observational cross-sectional descriptive study carried out from november of 2005 to march of 2006, assessing the nutritional status of all patients aged > or = 18 years with resectable digestive neoplasm submitted to scheduled surgery at the General and Digestive Surgery Department of the Hospital Complex of Orense (Spain). Eighty patients were studied, 41 men and 39 women aged 27-92 years. RESULTS: Diagnosis categorization was as follows: colonic neoplasm 27 patients, rectal neoplasm 24, gastric neoplasm 23, and pancreatic neoplasm 6. Fifty-three percent of the patients assessed had lost 5% of their usual weight within the previous 3 months. Serum albumin levels were lower than 3.5 mg/dL in 49% of the cases. Patient-Generated Subjective Global Assessment shows a hyponutrition prevalence of 50% (29% with moderate hyponutrition or at risk for hyponutrition and 21% with severe hyponutrition). Hyponutrition was related to age, increasing with increasing age (p < 0.05), and to the kind of digestive neoplasm (higher prevalence among patients with gastric neoplasm). CONCLUSIONS: Hyponutrition prevalence among patients with resectable digestive neoplasm is high. There is a similarity between the relative data relating to percentage of weight loss, serum albumin levels, and nutritional assessment obtained by applying the Patient-Generated Subjective Global Assessment. Further studies on hyponutrition prevalence among oncologic patients at our setting would be desirable.

Prevalencia de desnutrición en pacientes con neoplasia digestiva previa cirugía / Hyponutrition prevalence among patients with digestive beoplasm befote surgery

Objetivo: Analizar la prevalencia y el grado de desnutrición de los pacientes con neoplasia digestiva resecable que van a ser sometidos a intervención quirúrgica. Material y método: Estudio transversal, observacional y descriptivo de noviembre de 2005 a marzo de 2006 basado en la valoración nutricional de todos los pacientes mayores de edad con neoplasia digestiva resecable programados para intervención quirúrgica en el Servicio de Cirugía General y Digestiva del Complexo Hospitalario de Ourense. Se incluyeron 80 pacientes, 41 hombres y 39 mujeres de edades comprendidas entre los 27 y los 92 años. Resultados: La distribución por diagnósticos fue la siguiente: neoplasia de colon 27 pacientes, neoplasia de recto 24, neoplasia gástrica 23 y neoplasia pancreática 6. El 53% de los pacientes valorados había perdido más de un 5% de su peso habitual en los 3 meses previos. Las cifras de albúmina plasmática eran inferiores a 3,5 mg/dl en el 49% de los casos. La Valoración Global Subjetiva Generada por el Paciente muestra una prevalencia de desnutrición del 50% (29% desnutrición moderada o riesgo de desnutrición y 21% desnutrición severa). La desnutrición se relacionó con la edad, siendo más frecuente al aumentar ésta (p < 0,05) y con el tipo de neoplasia digestiva (mayor prevalencia en pacientes con neoplasia gástrica). Conclusiones: La prevalencia de desnutrición en pacientes con neoplasia digestiva resecable es elevada. Existe similitud entre los datos relativos al porcentaje de pérdida de peso, cifras de albúmina plasmática y valoración nutricional obtenida al aplicar la Valoración Global Subjetiva Generada por el Paciente. Sería deseable que se realizasen más estudios de prevalencia de desnutrición en pacientes oncológicos en nuestro medio (AU)

Objective: To analyze the prevalence and degree of hyponutrition among patients with resectable digestive neoplasm that will be submitted to surgery. Material and methods: Observational cross-sectional descriptive study carried out from november of 2005 to march of 2006, assessing the nutritional status of all patients aged ≥18 years with resectable digestive neoplasm submitted to scheduled surgery at the General and Digestive Surgery Department of the Hospital Complex of Orense (Spain). Eighty patients were studied, 41 men and 39 women aged 27-92 years. Result: Diagnosis categorization was as follows: colonic neoplasm 27 patients, rectal neoplasm 24, gastric neoplasm 23, and pancreatic neoplasm 6. Fifty-three percent of the patients assessed had lost 5% of their usual weight within the previous 3 months. Serum albumin levels were lower than 3.5 mg/dL in 49% of the cases. Patient-Generated Subjective Global Assessment shows a hyponutrition prevalence of 50% (29% with moderate hyponutrition or at risk for hyponutrition and 21% with severe hyponutrition). Hyponutrition was related to age, increasing with increasing age (p < 0.05), and to the kind of digestive neoplasm (higher prevalence among patients with gastric neoplasm). Conclusion: Hyponutrition prevalence among patients with resectable digestive neoplasm is high. There is a similarity between the relative data relating to percentage of weight loss, serum albumin levels, and nutritional assessment obtained by applying the Patient-Generated Subjective Global Assessment. Further studies on hyponutrition prevalence among oncologic patients at our setting would be desirable (AU)

Rabdomiolisis probablemente causada por interacción entre efalizumab y pravastatina / No disponible

No disponible

Readministración de drotrecogina alfa en paciente con enfermedad de Crohn / No disponible

No disponible