ABSTRACT
OBJECTIVES: The aim of this work was the assessment of correlation between different types of HPV and chosen factors: the number of pregnancies, childbirths and smoking habits. MATERIALS AND METHODS: Patients were examined in the Gynaecology Clinic, Silesian Medical Academy in Zabrze from 1998 until 2000. They were either hospital patients or women subjected to routine cytological examination. The smears were simultaneously collected for both cytooncologic examination and PCR identification of HPV viruses. Cytological smears were classified according to the Bethesda system. RESULTS: A relationship between the presence of HPV and number of pregnancies or childbirths was confirmed as well as the relationship between smoking and the presence of HPV genome. The higher number of pregnancies or childbirths the higher frequency of HPV presence is. HPV presence was more frequent in the group of smoking women. CONCLUSIONS: A relationship between the presence of HPV and the number of past childbirth or pregnancies was found. The statistically significant correlation between smoking and the risk of HPV infection was also confirmed.
Subject(s)
Papillomaviridae , Papillomavirus Infections/etiology , Tumor Virus Infections/etiology , Adult , Aged , Female , Gravidity , Humans , Middle Aged , Papillomaviridae/isolation & purification , Papillomavirus Infections/diagnosis , Papillomavirus Infections/epidemiology , Papillomavirus Infections/virology , Parity , Poland/epidemiology , Pregnancy , Risk Assessment , Risk Factors , Smoking/adverse effects , Surveys and Questionnaires , Tumor Virus Infections/diagnosis , Tumor Virus Infections/epidemiology , Tumor Virus Infections/virology , Vaginal SmearsABSTRACT
OBJECTIVES: The aim of this work was the assessment of the correlation between different types of HPV and abnormal stages of uterine cervix. MATERIALS AND METHODS: The smears were simultaneously collected for both cytooncologic examination and PCR identification of HPV viruses. Cytologic smears were classified according to the Bethesda system. RESULTS: A strong relationship between the presence of HPV types 16, 18 and 33 and the intensification of cytologic changes was confirmed. The more advanced abnormal changes in the uterine cervix, the more often presence of these HPV types. The presence of HPV types 6 and 11 were more often in low grade lesions. CONCLUSIONS: The conclusions from this examinations are: there is a proportional correlation between the grades of Squamous Intraepithelial Lesions, uterine cervix carcinoma and the presence of oncogenic types of human papillomavirus.
