Subject(s)
Lymphoma, T-Cell, Cutaneous/epidemiology , Neoplasm Staging/methods , Skin Neoplasms/epidemiology , Tertiary Care Centers , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Incidence , Lymphoma, T-Cell, Cutaneous/diagnosis , Male , Middle Aged , Retrospective Studies , Skin Neoplasms/diagnosis , Spain/epidemiology , Young AdultSubject(s)
Alopecia/complications , Scalp Dermatoses/complications , Steatocystoma Multiplex/complications , Adult , Alopecia/congenital , Diagnosis, Differential , Epidermal Cyst/diagnosis , Female , Humans , Scalp Dermatoses/diagnosis , Scalp Dermatoses/pathology , Steatocystoma Multiplex/diagnosis , Steatocystoma Multiplex/pathology , Steatocystoma Multiplex/surgeryABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Dermoscopy , Apocrine Glands/pathology , Sweat Gland Neoplasms/pathologySubject(s)
Apocrine Glands/pathology , Dermoscopy , Sweat Gland Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle AgedABSTRACT
El carcinoma sebáceo es un tumor anexial raro y agresivo. Su etiología es desconocida. El 75% de estos tumores son de localización periocular y el 25% extraocular. Es uno de los marcadores cutáneos diagnósticos del síndrome de Muir-Torre, una enfermedad genética asociada a neoplasias viscerales. Por lo tanto, los pacientes con carcinoma sebáceo deben ser cuidadosamente valorados, realizándose una historia oncológica personal y familiar adecuada, una exploración física cuidadosa, pruebas complementarias necesarias y un seguimiento estrecho. Se presentan 2 casos de carcinomas sebáceos extraoculares y se realiza una revisión de la literatura, destacando la asociación entre el carcinoma sebáceo y el síndrome de Muir-Torre (AU)
Sebaceous carcinoma is a rare, aggressive adnexal tumor of unknown etiology; 75% of these tumors arise in the periocular region while 25% arise at extraocular sites. This cutaneous tumor is a diagnostic sign of Muir-Torre syndrome, a disorder associated with visceral malignancies and gene abnormalities. Patients with sebaceous carcinoma should therefore be carefully evaluated; a detailed personal and family history of cancer, a thorough physical examination, additional tests where appropriate, and close monitoring will all be required. We report 2 cases of extraocular sebaceous carcinoma and review the literature, focusing on the association between sebaceous carcinoma and Muir-Torre syndrome (AU)
Subject(s)
Humans , Sebaceous Gland Neoplasms/pathology , Adenocarcinoma, Sebaceous/pathology , Muir-Torre Syndrome/complications , Risk FactorsABSTRACT
Sebaceous carcinoma is a rare, aggressive adnexal tumor of unknown etiology; 75% of these tumors arise in the periocular region while 25% arise at extraocular sites. This cutaneous tumor is a diagnostic sign of Muir-Torre syndrome, a disorder associated with visceral malignancies and gene abnormalities. Patients with sebaceous carcinoma should therefore be carefully evaluated; a detailed personal and family history of cancer, a thorough physical examination, additional tests where appropriate, and close monitoring will all be required. We report 2 cases of extraocular sebaceous carcinoma and review the literature, focusing on the association between sebaceous carcinoma and Muir-Torre syndrome.
Subject(s)
Adenocarcinoma, Sebaceous , Sebaceous Gland Neoplasms , Skin Neoplasms , Adenocarcinoma, Sebaceous/complications , Adenocarcinoma, Sebaceous/pathology , Aged, 80 and over , Female , Humans , Middle Aged , Muir-Torre Syndrome/complications , Sebaceous Gland Neoplasms/complications , Sebaceous Gland Neoplasms/pathology , Skin Neoplasms/complications , Skin Neoplasms/pathologyABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Middle Aged , Lupus Erythematosus, Cutaneous/drug therapy , Antibodies, Monoclonal/therapeutic use , Carbamazepine/therapeutic useSubject(s)
Antibodies, Monoclonal, Murine-Derived/therapeutic use , Immunosuppressive Agents/therapeutic use , Lupus Erythematosus, Cutaneous/drug therapy , Adult , Anticonvulsants/therapeutic use , Antimalarials/therapeutic use , Drug Resistance , Drug Therapy, Combination , Epilepsy/complications , Epilepsy/drug therapy , Etanercept , Female , Humans , Immunoglobulin G/therapeutic use , Immunoglobulins, Intravenous/therapeutic use , Immunosuppressive Agents/administration & dosage , Immunosuppressive Agents/adverse effects , Lupus Erythematosus, Systemic/complications , Middle Aged , Prednisone/therapeutic use , Receptors, Tumor Necrosis Factor/therapeutic use , Remission Induction , Rituximab , Thalidomide/therapeutic useABSTRACT
Sebaceous carcinoma is a rare, aggressive adnexal tumor of unknown etiology; 75% of these tumors arise in the periocular region while 25% arise at extraocular sites. This cutaneous tumor is a diagnostic sign of Muir-Torre syndrome, a disorder associated with visceral malignancies and gene abnormalities. Patients with sebaceous carcinoma should therefore be carefully evaluated; a detailed personal and family history of cancer, a thorough physical examination, additional tests where appropriate, and close monitoring will all be required. We report 2 cases of extraocular sebaceous carcinoma and review the literature, focusing on the association between sebaceous carcinoma and Muir-Torre syndrome.
