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Pol J Pathol ; 48(1): 63-7, 1997.
Article in English | MEDLINE | ID: mdl-9200963

ABSTRACT

Pulmonary infiltrates developed in a 40-year-old man while receiving arechine. The hyperplasia of mast cells, hyperlymphocytosis, a predominance of cytotoxic T-cells of the CD8 type with the very low CD4/CD8 ratio in BAL were observed. The chest roentgenogram findings resolved within a month after discontinuing arechine therapy. A hypersensitivity reaction with the onset of lung fibrosis due to arechine seemed to be the likely cause.


Subject(s)
Bronchoalveolar Lavage Fluid/cytology , Cell Movement/drug effects , Chloroquine/adverse effects , Lung/pathology , Lymphocytosis/pathology , Mastocytosis/pathology , Adult , Fibrosis , Humans , Lung/drug effects , Lymphocytosis/chemically induced , Male , Mastocytosis/chemically induced
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