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6.
Arch. Soc. Esp. Oftalmol ; 93(12): 606-609, dic. 2018. ilus
Article in Spanish | IBECS | ID: ibc-175155

ABSTRACT

CASO CLÍNICO: Un varón de 70 años, procedente de Sicilia, acude con una masa palpebral bilateral con afectación tarsal conjuntival, que resultó ser un sarcoma de Kaposi al examen histológico. Se demostró afectación cutánea y pulmonar por el sarcoma de Kaposi. El paciente no tenía un diagnóstico previo de infección por el virus de la inmunodeficiencia humana. Este caso fue tratado con éxito tras 5 ciclos de quimioterapia con doxorrubicina liposomal, con resolución de las lesiones palpebrales, cutáneas y pulmonares. Conclusiones: La localización en el párpado es una posible manifestación inicial, aunque rara, del sarcoma de Kaposi en personas de edad avanzada negativos para el virus de la inmunodeficiencia humana. La doxorrubicina liposomal es un tratamiento seguro y efectivo


CASE REPORT: We report a case of 70-year-old male from Sicily, who presented with a bilateral eyelid mass involving the tarsal conjunctiva, found to be Kaposi's sarcoma on histologic examination. Cutaneous and pulmonary Kaposi's sarcoma involvement was documented. The patient had no prior diagnosis of human immunodeficiency virus infection. This case was managed successfully after the completion of five cycles of chemotherapy with liposomal doxorubicin, and his eyelid, skin and pulmonary lesions disappeared. CONCLUSIONS: Location in the eyelid is a possible, though rare, initial solitary manifestation of Kaposi's sarcoma in elderly HIV-negative patients. Liposomal doxorubicin is a safe and effective treatment


Subject(s)
Humans , Male , Aged , Sarcoma, Kaposi/complications , Eyelid Diseases/pathology , Doxorubicin/therapeutic use , Visual Acuity , Biopsy , HIV Seronegativity , Conjunctiva/pathology , Eyelids/pathology , Diagnosis, Differential , Immunohistochemistry , Enzyme-Linked Immunosorbent Assay , Blotting, Western , Sarcoma, Kaposi/diagnostic imaging , Sarcoma, Kaposi/therapy
9.
Arch Soc Esp Oftalmol (Engl Ed) ; 93(12): 606-609, 2018 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-30055902

ABSTRACT

CASE REPORT: We report a case of 70-year-old male from Sicily, who presented with a bilateral eyelid mass involving the tarsal conjunctiva, found to be Kaposi's sarcoma on histologic examination. Cutaneous and pulmonary Kaposi's sarcoma involvement was documented. The patient had no prior diagnosis of human immunodeficiency virus infection. This case was managed successfully after the completion of five cycles of chemotherapy with liposomal doxorubicin, and his eyelid, skin and pulmonary lesions disappeared. CONCLUSIONS: Location in the eyelid is a possible, though rare, initial solitary manifestation of Kaposi's sarcoma in elderly HIV-negative patients. Liposomal doxorubicin is a safe and effective treatment.


Subject(s)
Antibiotics, Antineoplastic/therapeutic use , Doxorubicin/analogs & derivatives , Eyelid Neoplasms/drug therapy , Neoplasms, Multiple Primary/drug therapy , Sarcoma, Kaposi/drug therapy , Aged , Doxorubicin/therapeutic use , Eyelid Neoplasms/diagnostic imaging , HIV Seronegativity , Humans , Male , Neoplasms, Multiple Primary/diagnostic imaging , Polyethylene Glycols/therapeutic use , Remission Induction , Sarcoma, Kaposi/diagnostic imaging , Tomography, X-Ray Computed
12.
J Fr Ophtalmol ; 41(4): 326-332, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29681466

ABSTRACT

INTRODUCTION: To determine outcomes of conjunctival autograft attached with fibrin glue (FG) for primary pterygium, and compare these outcomes in expert versus closely supervised trainee ophthalmologists. METHODS: This was a retrospective, comparative, non-randomized, interventional study. Patients were recruited among those with primary nasal pterygium undergoing FG conjunctival autograft. Surgery was performed by expert (136 eyes) or closely supervised trainee (128 eyes) ophthalmologists. Mean follow-up was 7.82±8.23months. Main outcome measures were recurrence rate, reoperation rate and complications. RESULTS: The study sample comprised 264 eyes of 225 patients. Participants were of mean age 47.09±12.89years; 46.7% were male, 28.4% Caucasian and 70.5% Hispanic. Recurrence was recorded in 6.4%: 5.9% in the expert group and 7% in the trainee group (P=0.704) and reoperation in 1.9%: 0.7% and 3.1% (P=0.202), respectively. Both groups showed similar rates of complications such as transient graft edema, graft dehiscence, hematoma or ocular hypertension. Reoperation was slightly more frequent in patients younger than 40years (P=0.064). CONCLUSIONS: Good outcomes were observed for FG conjunctival autografting in primary pterygium surgery, with no differences recorded between supervised trainee and expert surgeons. Our findings suggest the need to supervise pterygium surgeries during training.


Subject(s)
Conjunctiva/transplantation , Fibrin Tissue Adhesive/therapeutic use , Ophthalmologists/education , Pterygium/surgery , Transplantation, Autologous/methods , Adult , Aged, 80 and over , Autografts , Female , Follow-Up Studies , Humans , Learning Curve , Male , Middle Aged , Organization and Administration , Postoperative Complications/epidemiology , Recurrence , Reoperation/statistics & numerical data , Retrospective Studies , Treatment Outcome , Young Adult
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