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1.
Rev Assoc Med Bras (1992) ; 51(2): 93-9, 2005.
Article in Portuguese | MEDLINE | ID: mdl-15947822

ABSTRACT

UNLABELLED: The main goals of the larynx preservation protocol are eradication of cancer and preservation of a functional larynx with maintenance of respiration, phonation and swallowing. Few studies, however have addressed functional outcomes. OBJECTIVE: Functional evaluation of oropharyngeal swallowing in patients enrolled in a larynx preservation protocol at the Hospital do Câncer AC Camargo. METHODS: Evaluation of swallowing was performed by videofluoroscopy in 31 patients, focusing on: oropharyngeal motility disorders, stasis, laryngeal penetration, aspiration and severity of dysphagia. RESULTS: Swallowing analysis: 5 patients showed inefficient bolus preparation, 14 had changes in the bolus propulsion; 23 patients had a reduced laryngeal elevation, 26 presented with stasis in the vallecula and 14 with stasis in hypopharynx. Nine patients presented silent aspiration. We detected functional swallowing in 11 patients; mild dysphagia in 7; mild/moderate in 7; moderate in 3 and severe dysphagia in 3. CONCLUSION: Larynx preservation results in changes of swallowing, ranging in their majority from discrete to moderate. Some patients, however, developed severe dysphagia, and oral feeding was not possible.


Subject(s)
Carcinoma, Squamous Cell/physiopathology , Deglutition Disorders/physiopathology , Hypopharyngeal Neoplasms/physiopathology , Laryngeal Neoplasms/physiopathology , Adult , Aged , Antineoplastic Agents/therapeutic use , Carcinoma, Squamous Cell/drug therapy , Carcinoma, Squamous Cell/radiotherapy , Cisplatin/therapeutic use , Combined Modality Therapy , Deglutition Disorders/etiology , Dyspepsia/etiology , Female , Fluoroscopy , Humans , Hypopharyngeal Neoplasms/complications , Hypopharyngeal Neoplasms/drug therapy , Hypopharyngeal Neoplasms/radiotherapy , Laryngeal Neoplasms/drug therapy , Laryngeal Neoplasms/radiotherapy , Male , Middle Aged , Paclitaxel/analogs & derivatives , Paclitaxel/therapeutic use , Severity of Illness Index , Treatment Outcome , Video Recording
2.
Rev. Assoc. Med. Bras. (1992, Impr.) ; 51(2): 93-99, mar.-abr. 2005. tab, graf
Article in Portuguese | LILACS | ID: lil-411146

ABSTRACT

OBJETIVO: Avaliar a deglutição orofaríngea de pacientes submetidos a protocolo de preservação de laringe no Hospital do Câncer AC Camargo. MÉTODOS: De 43 pacientes com carcinoma epidermóide de laringe e hipofaringe tratados com quimioterapia semanal (paclitaxel 30 mg/m² e cisplatina 20 mg/m²) concomitante à radioterapia externa fracionada (180 cGy/dia, dose total 7040 cGy), foram avaliados 31 pacientes. A avaliação consistiu de videofluoroscopia. Os resultados foram classificados de acordo com alterações de motilidade orofaríngea, estases, aspiração e severidade da disfagia. RESULTADOS: alterações de fase preparatória e oral: estase em cavidade oral (58 por cento) e aumento do tempo de trânsito oral (32,3 por cento); fase faríngea: estase em valécula (83,9 por cento), redução da elevação laríngea (74,2 por cento), atraso no início da deglutição faríngea (51,6 por cento) e estase em hipofaringe (45,2 por cento). A deglutição funcional foi observada em 35,5 por cento dos pacientes, 54,8 por cento tinham disfagias discretas ou moderadas e 9,6 por cento disfagias severas. CONCLUSÃO: A associação de quimioterapia e radioterapia para preservação laríngea resulta em alterações da deglutição, na maior parte discretas a moderadas. Alguns pacientes, entretanto, evoluem com disfagia severa, em que a alimentação por via oral não é possível.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Carcinoma, Squamous Cell/physiopathology , Deglutition Disorders/physiopathology , Hypopharyngeal Neoplasms/physiopathology , Laryngeal Neoplasms/physiopathology , Antineoplastic Agents/therapeutic use , Carcinoma, Squamous Cell/drug therapy , Carcinoma, Squamous Cell/radiotherapy , Cisplatin/therapeutic use , Combined Modality Therapy , Deglutition Disorders/etiology , Dyspepsia/etiology , Fluoroscopy , Hypopharyngeal Neoplasms/complications , Hypopharyngeal Neoplasms/drug therapy , Hypopharyngeal Neoplasms/radiotherapy , Laryngeal Neoplasms/drug therapy , Laryngeal Neoplasms/radiotherapy , Paclitaxel/analogs & derivatives , Paclitaxel/therapeutic use , Severity of Illness Index , Treatment Outcome , Video Recording
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