[Experimental data on pharmacological effects of new phenothiazine derivatives]. / Données expérimentales concernant les effets pharmacologiques de quelques nouveaux dérivés phénothiaziniques.

A variety of triazoles and thiadiazoles linked to the N-atom of the phenothiazine through a two carbon atoms chain have been submitted to preliminary toxicological screening (DL50 and DMT). Two derivatives have been selected for the specific pharmacological evaluation. It has been noted a diminution of the exploratory capacity without the muscle tonus, the balance and the capacity of becoming normal again of the tested animals (mice and rats) being affected.

Analog decoding using a gradient-type neural network.

The problem of analog (soft) decision decoding of block codes by means of neural networks is addressed. The proposed solution is based on a recurrent high-order network implementing a special gradient-type system. Simulation results for two different codes are reported, showing improved performances over the classical hard decision decoder.

[The synthesis of new pyrrolidone derivatives with psychotropic action]. / Sinteza unor noi derivati pirolidonici cu actiune psihotropa.

The synthesis of ten new heterocyclic compounds obtained by the addition of pyrrolidone to heterocumulenes and its condensation or of its sodic derivative with acid chlorides is presented. The synthetized pyrolidonic derivatives were subjected to a preliminary study for determining their possible psychotropic action. The pharmacological screening evidenced a significant hypothermisante and neurodynamic-nootropic action of some synthetized compounds.