ABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Choroid Diseases/diagnostic imaging , Choroid Diseases/etiology , Choroid/injuries , Rupture/diagnostic imaging , Rupture/etiology , Tomography, Optical Coherence , Computed Tomography AngiographyABSTRACT
No disponible
Subject(s)
Humans , Myopia/epidemiology , Visual Acuity , Retinal Detachment/complications , Risk Factors , Eyeglasses/trends , Hyperopia/epidemiology , Myopia/complications , Myopia/economics , Macular Degeneration/complications , Disease ProgressionSubject(s)
Myopia/therapy , Adolescent , Adult , Age of Onset , Atropine/therapeutic use , Child , Contact Lenses , Disease Progression , Eyeglasses , Humans , Incidence , Life Style , Lighting , Morbidity/trends , Myopia/epidemiology , Myopia/etiology , Myopia/prevention & control , Ophthalmic Solutions , Risk Factors , SunlightABSTRACT
CASO CLÍNICO: Mujer de 53 años con agujero macular estadio 2, que recibió como primera opción terapéutica una inyección de ocriplasmina, pero a la que se le tuvo que practicar vitrectomía pars plana por aumento del agujero macular postinyección. La ganancia visual tras la cirugía fue mínima a pesar del cierre del agujero, lo que podría explicarse por la atrofia retiniana externa como consecuencia de los potenciales mecanismos tóxicos asociados a ocriplasmina. Discusión: Son necesarios más estudios para entender el completo impacto de la ocriplasmina en la función visual a largo plazo
CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function
Subject(s)
Humans , Female , Middle Aged , Retinal Diseases/complications , Retinal Perforations/chemically induced , Retinal Perforations/surgery , Vitreous Detachment/drug therapy , Vitrectomy/methods , Fibrinolysin/administration & dosage , Intravitreal Injections , Treatment Failure , Retinal Diseases/chemically induced , Minimally Invasive Surgical Procedures/methods , Visual Acuity , Fibrinolysin/adverse effectsABSTRACT
CASE REPORT: A 53 year-old woman with a stage 2 macular hole received ocriplasmin injection as a first approach. She subsequently underwent pars plana vitrectomy due to enlargement of the hole post-injection. The visual gain following the surgery was minimal despite closure of the hole. This could be explained by outer retina atrophy as a consequence of potential toxic mechanisms related to ocriplasmin. DISCUSSION: Further studies may be warranted to fully understand the impact of ocriplasmin on long-term visual function.
Subject(s)
Fibrinolysin/adverse effects , Peptide Fragments/adverse effects , Retinal Diseases/chemically induced , Female , Fibrinolysin/therapeutic use , Humans , Middle Aged , Peptide Fragments/therapeutic use , Retinal Perforations/drug therapy , Treatment FailureABSTRACT
PROPÓSITO: Comparar el grosor coroideo subfoveal (GCSF) entre pacientes con edema macular diabético (EMD) y sujetos sanos mediante tomografía de coherencia óptica swept source (SS-OCT). MÉTODO: Estudio transversal con 50 ojos de 36 pacientes con EMD y 47 ojos de 34 pacientes como grupo control. Fue evaluado el GCSF en ambos grupos, realizándose además un análisis entre los ojos con EMD en función del tipo de edema (predominantemente quístico o difuso). RESULTADOS: Los grupos de estudio fueron homogéneos en cuanto a la edad media (63,4 años para EMD y 62,65 años para controles; p = 0,36) y la longitud axial media (23,21 mm para EMD y 23,53 mm para controles; p = 0,06). Se objetivó una reducción estadísticamente significativa en el grosor coroideo entre los ojos con EMD respecto al grupo control (192,82 vs. 222,9 μm; p = 0,041). No se evidenciaron diferencias estadísticamente significativas en los ojos con EMD en función del patrón de edema predominantemente quístico y difuso (205,7 vs. 178,68 μm; p = 0,13). CONCLUSIÓN: El GCSF en pacientes con EMD podría encontrarse reducido, sin que el patrón de engrosamiento macular tomográfico se asocie a diferencias significativas en este sentido. Son necesarios futuros estudios para confirmar estos resultados preliminares
PURPOSE: To compare subfoveal choroidal thickness (GCSF) in patients with diabetic macular oedema (DMO) and healthy subjects using swept source optical coherence tomography (SS-OCT). METHOD: Cross-sectional study including 50 eyes of 36 patients with DMO, and 47 eyes of 34 patients as a control group. GCSF was measured in both groups, analysing between the eyes with DMO according to the type of oedema (predominantly cystic or diffuse). RESULTS: The study groups were homogeneous in terms of mean age (63.4 years for DMO and 62.65 years for controls; P=.36) and the mean axial length (23.21 mm for DME and 23.53 mm for controls; P=.06). A statistically significant reduction in the eye with DME GCSF compared to controls (P=.041, 222.9 vs. 192.82 μm) was observed. No statistically significant differences were observed in the eyes with DMO with a predominantly cystic pattern and diffuse oedema (P=.13, 178.68 vs. 205.7 μm). CONCLUSION: The GCSF in patients with DMO could be reduced. Future studies are needed to confirm these preliminary results
Subject(s)
Humans , Male , Female , Choroid/physiology , Choroid/injuries , Macular Edema/etiology , Macular Edema/pathology , Macular Edema/prevention & control , Tomography, Optical Coherence/instrumentation , Tomography, Optical Coherence/methods , Tomography, Optical Coherence , Diabetic Retinopathy/complications , Diabetic Retinopathy/diagnosis , Diabetic Retinopathy/prevention & control , Diabetes Complications/diagnosis , Diabetes Complications/prevention & control , Diabetes Complications/therapy , Cross-Sectional Studies , Retrospective StudiesABSTRACT
PURPOSE: To compare subfoveal choroidal thickness (GCSF) in patients with diabetic macular oedema (DMO) and healthy subjects using swept source optical coherence tomography (SS-OCT). METHOD: Cross-sectional study including 50 eyes of 36 patients with DMO, and 47 eyes of 34 patients as a control group. GCSF was measured in both groups, analysing between the eyes with DMO according to the type of oedema (predominantly cystic or diffuse). RESULTS: The study groups were homogeneous in terms of mean age (63.4 years for DMO and 62.65 years for controls; P=.36) and the mean axial length (23.21mm for DME and 23.53mm for controls; P=.06). A statistically significant reduction in the eye with DME GCSF compared to controls (P=.041, 222.9 vs. 192.82 µm) was observed. No statistically significant differences were observed in the eyes with DMO with a predominantly cystic pattern and diffuse oedema (P=.13, 178.68 vs. 205.7 µm). CONCLUSION: The GCSF in patients with DMO could be reduced. Future studies are needed to confirm these preliminary results.
Subject(s)
Choroid/pathology , Diabetic Retinopathy/pathology , Macular Edema/pathology , Tomography, Optical Coherence/methods , Cross-Sectional Studies , Diabetic Retinopathy/complications , Female , Humans , Macular Edema/complications , Male , Middle Aged , Retrospective StudiesABSTRACT
No disponible
Subject(s)
Adult , Humans , Male , Intravitreal Injections , Propranolol/therapeutic use , Retinal Detachment/complications , Retinal Detachment/diagnosis , Treatment Outcome , Hemangioblastoma/complications , Hemangioblastoma/diagnosis , Fundus Oculi , Ophthalmoscopy , Visual AcuityABSTRACT
No disponible
Subject(s)
Female , Humans , Male , Osmolar Concentration , Graft vs Host Disease/complications , Graft vs Host Disease/diagnosis , Xerophthalmia/complications , Ophthalmic Solutions/therapeutic use , Graft vs Host Disease/physiopathology , Graft vs Host Disease , Ophthalmic Solutions , Lubricant Eye Drops/therapeutic useABSTRACT
CASO CLÍNICO: Paciente sano de 20 años con pérdida de visión aguda en el ojo izquierdo. Al examen del fondo de ojo presentó una alteración macular compatible con coroiditis unifocal helioide caracterizada por ser una lesión inflamatoria atípica redondeada, solitaria, blanca-amarillenta, de aproximadamente del tamaño de un disco óptico. En el estudio etiológico se detectó leve positividad serológica de IgG (inmunoglobulinas G) Antitoxoplasma gondii. DISCUSIÓN: Una serología inespecífica y las características atípicas de la lesión limitan el diagnóstico. El coeficiente Goldmann-Witmer puede ser útil en el diagnóstico de lesiones localizadas al relacionar concentraciones entre IgG séricas y humor acuoso
CASE REPORT: A 20 year-old healthy patient consulted due to acute loss vision in his left eye. A fundus examination showed a macular alteration compatible with unifocal helioid choroiditis, characterized by being an atypical inflammatory yellow-white, round, single lesion of approximately an optic disc in diameter. The etiology study detected low Antitoxoplasma gondii Ig G (immunoglobulin) titers. DISCUSSION: The non-specificity of the serology and the atypical characteristics of the lesion is a limitation in the diagnosis. The Goldmann-Witmer coefficient may be useful in the diagnosis of atypical lesions, by comparing the concentration of IgG from the serum and aqueous humor
Subject(s)
Humans , Male , Young Adult , Choroiditis/diagnosis , Retinitis/diagnosis , Toxoplasma/isolation & purification , Toxoplasmosis/diagnosis , Tomography, Optical Coherence/methodsABSTRACT
No disponible
Subject(s)
Female , Humans , Male , Lasers/classification , Lasers , Lasers/supply & distribution , Lasers/standardsSubject(s)
Dry Eye Syndromes/drug therapy , Graft vs Host Disease/complications , Lubricant Eye Drops/therapeutic use , Dry Eye Syndromes/etiology , Dry Eye Syndromes/physiopathology , Humans , Hypotonic Solutions/therapeutic use , Osmolar Concentration , Surface Properties , Tears/chemistry , Tears/physiology , Tomography, Optical CoherenceABSTRACT
No disponible
Subject(s)
Adult , Humans , Male , Pheochromocytoma/diagnosis , Pheochromocytoma/pathology , Hypertension/complications , Hypertension/diagnosis , Vomiting/diagnosis , Retinal Hemorrhage/complications , Hypertensive Retinopathy/complications , Hypertensive Retinopathy/diagnosis , Pheochromocytoma/complications , Pheochromocytoma , Hypertension/classification , Hypertension/prevention & control , Vomiting/enzymology , Vomiting/metabolism , Retinal Hemorrhage/metabolism , Headache/pathologyABSTRACT
CASE REPORT: A 20 year-old healthy patient consulted due to acute loss vision in his left eye. A fundus examination showed a macular alteration compatible with unifocal helioid choroiditis, characterized by being an atypical inflammatory yellow-white, round, single lesion of approximately an optic disc in diameter. The etiology study detected low Antitoxoplasma gondii Ig G (immunoglobulin) titers. DISCUSSION: The non-specificity of the serology and the atypical characteristics of the lesion is a limitation in the diagnosis. The Goldmann-Witmer coefficient may be useful in the diagnosis of atypical lesions, by comparing the concentration of IgG from the serum and aqueous humor.
Subject(s)
Algorithms , Antibodies, Protozoan/analysis , Aqueous Humor/immunology , Choroiditis/diagnosis , Immunoglobulin G/analysis , Toxoplasma/immunology , Toxoplasmosis, Ocular/diagnosis , Antibodies, Protozoan/blood , Choroiditis/diagnostic imaging , Choroiditis/drug therapy , Choroiditis/etiology , Fluorescein Angiography , Humans , Immunoglobulin G/blood , Male , Prednisolone/therapeutic use , Retinal Detachment/etiology , Retinal Hemorrhage/etiology , Toxoplasmosis, Ocular/diagnostic imaging , Toxoplasmosis, Ocular/drug therapy , Toxoplasmosis, Ocular/immunology , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , Vision Disorders/etiology , Young AdultSubject(s)
Adrenal Gland Neoplasms/complications , Hypertensive Retinopathy/etiology , Pheochromocytoma/complications , Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/diagnostic imaging , Adrenal Gland Neoplasms/surgery , Adrenalectomy , Adult , Emergencies , Headache/etiology , Humans , Hyperhidrosis/etiology , Hypertension, Malignant/etiology , Hypertensive Retinopathy/diagnostic imaging , Magnetic Resonance Imaging , Male , Pheochromocytoma/diagnosis , Pheochromocytoma/diagnostic imaging , Pheochromocytoma/surgery , Remission Induction , Retinal Hemorrhage/etiology , Tomography, Optical CoherenceSubject(s)
Adrenergic beta-Antagonists/therapeutic use , Angiogenesis Inhibitors/therapeutic use , Hemangioblastoma/complications , Propranolol/therapeutic use , Ranibizumab/therapeutic use , Retinal Detachment/drug therapy , Retinal Neoplasms/complications , Administration, Oral , Adrenergic beta-Antagonists/administration & dosage , Adult , Angiogenesis Inhibitors/administration & dosage , Combined Modality Therapy , Drug Therapy, Combination , Humans , Intravitreal Injections , Laser Coagulation , Male , Propranolol/administration & dosage , Ranibizumab/administration & dosage , Recurrence , Retinal Detachment/etiology , Retinal Detachment/surgeryABSTRACT
PURPOSE: An analysis is made of a serious late complication (opacification) of different models of hydrophilic acrylic intraocular lenses (IOLs). METHODS: Seven lenses were explanted from seven patients treated for cataracts with phacoemulsification and implantation of different types of hydrophilic acrylic IOLs (five SC60B-OUV from MDR, one Aquasense from OII, and one H60M Hydroview lens from Bausch & Lomb) who developed important vision impairment in the late postoperative period (1 to 3 years) due to lens opacification. The explanted lenses were subjected to exhaustive study involving photographic analysis, scanning electron microscopy, and energy dispersive X-ray spectroscopy. RESULTS: Light and scanning electron microscopy revealed diffuse, variable-size granular deposits within the optic of the SC60B-OUV lens, and on the anterior and posterior optic surfaces of the H60M Hydroview lens, though without affecting the haptics in any of the models. Dispersive energy X-ray spectroscopy of the deposits revealed the presence mainly of calcium and phosphorus salts. CONCLUSIONS: Hydrophilic acrylic IOL opacification is a serious late complication of unknown etiology. The condition is more frequent among diabetic patients, and the only management option is IOL explantation and replacement with a lens of some other material. More frequent and longer follow-up is required of those patients wearing lenses for which cases of opacification have been documented, particularly in the presence of predisposing factors (diabetes, uveitis). Caution is required with new lenses, avoiding their generalized use until they have successfully passed the test of time.
