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J Clin Densitom ; 15(1): 116-9, 2012.
Article in English | MEDLINE | ID: mdl-22154431

ABSTRACT

Human progeroid syndromes (PSs) include a group of genetic "premature aging" diseases that affect a variety of organ systems. Bone diseases are common sequelae of patients diagnosed with PSs. Teriparatide therapy is recommended for elderly men with low bone mineral density (BMD; T-score <-2.5) and at least 1 fragility fracture who are unable to tolerate bisphosphonates. We describe a 20-yr-old patient affected by PS and severe osteoporosis complicated with femoral fracture. The patient experienced a significant improvement in lumbar spine BMD after treatment with teriparatide.


Subject(s)
Bone Density Conservation Agents/therapeutic use , Osteoporosis/drug therapy , Osteoporosis/etiology , Progeria/complications , Bone Density , Humans , Male , Syndrome , Teriparatide/therapeutic use , Young Adult
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