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1.
Regen Med ; 16(1): 87-100, 2021 01.
Article in English | MEDLINE | ID: mdl-33533657

ABSTRACT

The purpose of this manuscript is to highlight and review the status of literature regarding efficacy of platelet-rich plasma (PRP) in the treatment of sacroiliac joint (SIJ) dysfunction. A review of the literature on PRP interventions on the SIJ or ligaments was performed. Seven studies had improvements in their respective primary end point and demonstrated a strong safety profile without any serious adverse events. Only five articles demonstrated clinical efficacy of >50% in their primary outcome measures. There appears to be inconsistent and insufficient evidence for a conclusive recommendation for or against SIJ PRP. There is a need for adequately powered well-designed, standardized, double-blinded randomized clinical trials to determine the effectiveness of PRP in SIJ-mediated pain.


Subject(s)
Low Back Pain , Platelet-Rich Plasma , Back Pain , Humans , Sacroiliac Joint , Treatment Outcome
2.
Knee Surg Sports Traumatol Arthrosc ; 26(4): 1096-1103, 2018 Apr.
Article in English | MEDLINE | ID: mdl-28321475

ABSTRACT

PURPOSE: Limited objective data exist detailing the quantitative anatomy of the individual bundles of the proximal tibiofibular joint and their relation to surgically pertinent osseous landmarks. The purpose of this study was to qualitatively and quantitatively describe the ligamentous anatomy of the proximal tibiofibular joint and its relation to relevant bony landmarks. METHODS: Ten non-paired, fresh-frozen cadaveric knee specimens were dissected to identify the proximal tibiofibular joint ligament bundles. Pertinent bony landmarks were identified and served as reference points for the tibial and fibular attachments for each bundle. Ligament bundle footprints, lengths and orientations were measured using a 3D coordinate measuring device. RESULTS: Up to four bundles were identified anteriorly and up to three bundles posteriorly. The inferior bundle was identified anteriorly and posteriorly in 60% and 20% of the cases, respectively. For the anterior complex, the centres of the tibial attachments were a mean distance of 12.5 mm (95% CI [10.7, 14.3]) and 25.3 mm (95% CI [21.6, 29.0]) from the tibial plateau for the superior and inferior bundles, respectively. The centres of the fibular attachments were 11.3 mm (95% CI [7.4, 15.1]) and 27.0 mm (95% CI [24.0, 30.0]) from the apex of the fibular styloid for the superior and inferior bundles, respectively. For the bundles of the posterior complex, the centres of the tibial attachments were 13.4 mm (95% CI [11.6, 15.2]) and 38.8 mm (95% CI [31.0, 46.6]) distal to the tibial plateau for the superior and inferior bundles, respectively, and the centres of the fibular attachments were 8.0 mm (95% CI [5.8, 10.1]) and 29.3 mm (95% CI [25.5, 33.1]) from the apex of the fibular styloid for the superior and inferior bundles, respectively. In the coronal plane, the mean 2D angle between the medial to lateral knee joint axis and the axis passing through the centre of the proximal tibiofibular joint and the centre of the tibial plateau was 16.9° (95% CI [12.8, 21.0]). CONCLUSION: The ligament bundles of the proximal tibiofibular joint were reproducibly identified between specimens in relation to surrounding bony landmarks. Up to four bundles were identified in the anterior ligament complex and up to three in the posterior complex. Variation in bundle orientation and footprint size was observed. Based on these findings, an anatomic reconstruction can be performed using surrounding reliable landmarks.


Subject(s)
Anatomic Landmarks/anatomy & histology , Fibula/anatomy & histology , Knee Joint/anatomy & histology , Ligaments, Articular/anatomy & histology , Tibia/anatomy & histology , Aged , Female , Humans , Male , Middle Aged
3.
Am J Sports Med ; 46(3): 687-694, 2018 03.
Article in English | MEDLINE | ID: mdl-29266961

ABSTRACT

BACKGROUND: The anterior bundle of the medial ulnar collateral ligament (UCL) and the forearm flexors provide primary static and dynamic stability to valgus stress of the elbow in overhead-throwing athletes. Quantitative anatomic relationships between the dynamic and static stabilizers have not been described. PURPOSE: To perform qualitative and quantitative anatomic evaluations of the medial elbow-UCL complex with specific attention to pertinent osseous and soft tissue landmarks. STUDY DESIGN: Descriptive laboratory study. METHODS: Ten nonpaired, fresh-frozen human cadaveric elbows (mean age, 54.1 years [range, 42-64 years]; all male) were utilized for this study. Quantitative analysis was performed with a 3-dimensional coordinate measuring device to quantify the location of pertinent bony landmarks and tendon and ligament footprints on the humerus, ulna, and radius. RESULTS: The anterior bundle of the UCL attached 8.5 mm (95% CI, 6.9-10.0) distal and 7.8 mm (95% CI, 6.6-9.1) lateral to the medial epicondyle, 1.5 mm (95% CI, 0.5-2.5) distal to the sublime tubercle, and 7.3 mm (95% CI, 6.1-8.5) distal to the joint line on the ulna along the ulnar ridge. The flexor digitorum superficialis (FDS) ulnar tendinous insertion was closely related and interposed within the anterior bundle of the UCL, overlapping with 45.6% (95% CI, 38.1-53.6) of the length of the anterior bundle of the UCL. The flexor carpi ulnaris (FCU) attached 1.9 mm (95% CI, 0.8-2.9) posterior and 1.3 mm (95% CI, 0.6-3.2) proximal to the sublime tubercle and overlapped with 20.9% (95% CI, 7.2-34.5) of the area of the distal footprint of the anterior bundle of the UCL. CONCLUSION: The anterior bundle of the UCL had consistent attachment points relative to the medial epicondyle and sublime tubercle. The ulnar limb of the FDS and FCU tendons demonstrated consistent insertions onto the ulnar attachment of the anterior bundle of the UCL. These anatomic relationships are important to consider when evaluating distal UCL tears both operatively and nonoperatively. Excessive stripping of the sublime tubercle should be avoided during UCL reconstruction to prevent violation of these tendinous attachments. CLINICAL RELEVANCE: The findings of this study enhance the understanding of valgus restraint in throwing athletes and provide insight into the difference in nonoperative outcomes between proximal and distal tears of the UCL.


Subject(s)
Elbow/anatomy & histology , Adult , Cadaver , Collateral Ligament, Ulnar/anatomy & histology , Forearm , Humans , Male , Middle Aged , Muscle, Skeletal/anatomy & histology , Tendons/anatomy & histology
4.
Arthroscopy ; 32(9): 1919-25, 2016 09.
Article in English | MEDLINE | ID: mdl-27234653

ABSTRACT

PURPOSE: To systematically review meniscal radial tear repair procedures and compare the techniques, outcomes, and complications. METHODS: Studies were identified through a systematic review of the literature using the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, PubMed (1980-2014), Medline (1980-2014), and Embase. Inclusion criteria included a minimum follow-up of 24 months, English language, and publications from 1980 or later. Exclusion criteria were surgical techniques not reporting follow-up, biomechanical studies, cadaver/anatomic studies, and non-radial tear meniscal repair procedures. Meniscal radial repair, meniscal radial tear, meniscal radial tear repair, radial repair and radial tear were used as search terms. RESULTS: A total of 6 studies (55 patients) met the inclusion criteria. The mean duration of follow-up ranged from 24 to 71 months. Of the 6 studies, 5 reported radial tears to the lateral meniscus and 1 study reported cases of both medial and lateral meniscal radial tears. Two studies reported different inside-out repair techniques, 2 studies reported the use of an all-inside anchor-based repair system, 1 study reported an all-inside repair technique with absorbable sutures, and 1 study reported an inside-out repair with fibrin clots. Average postoperative Lysholm scores were reported in all 6 studies and ranged from 86.9 to 95.6. Average postoperative Tegner activity scores were reported in 4 studies and ranged from 1 to 6.7. The majority of studies concluded that their techniques produced satisfactory healing of the radial tear, without serious subsequent complications. CONCLUSIONS: Radial repair techniques differed among studies; however, postoperative subjective outcomes revealed patient improvement with repairing radial tears. With the increasing concern of long-term osteoarthritis after meniscectomy, meniscal preservation with repair of radial tears results in improved short-term clinical outcomes; however, long-term outcomes remain unknown. LEVEL OF EVIDENCE: Level IV, systematic review of level IV studies.


Subject(s)
Arthroscopy/methods , Menisci, Tibial/surgery , Tibial Meniscus Injuries/surgery , Follow-Up Studies , Humans , Knee Injuries/surgery , Knee Joint/surgery , Lysholm Knee Score , Osteoarthritis/surgery , Postoperative Period , Sutures , Treatment Outcome
5.
Am J Sports Med ; 44(3): 639-45, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26646516

ABSTRACT

BACKGROUND: Complete radial tears of the medial meniscus have been reported to be functionally similar to a total meniscectomy. At present, there is no consensus on an ideal technique for repair of radial midbody tears of the medial meniscus. Prior attempts at repair with double horizontal mattress suture techniques have led to a reportedly high rate of incomplete healing or healing in a nonanatomic (gapped) position, which compromises the ability of the meniscus to withstand hoop stresses. HYPOTHESIS: A newly proposed 2-tunnel radial meniscal repair method will result in decreased gapping and increased ultimate failure loads compared with the double horizontal mattress suture repair technique under cyclic loading. STUDY DESIGN: Controlled laboratory study. METHODS: Ten matched pairs of male human cadaveric knees (average age, 58.6 years; range, 48-66 years) were used. A complete radial medial meniscal tear was made at the junction of the posterior one-third and middle third of the meniscus. One knee underwent a horizontal mattress inside-out repair, while the contralateral knee underwent a radial meniscal repair entailing the same technique with a concurrent novel 2-tunnel repair. Specimens were potted and mounted on a universal testing machine. Each specimen was cyclically loaded 1000 times with loads between 5 and 20 N before experiencing a load to failure. Gap distances at the tear site and failure load were measured. RESULTS: The 2-tunnel repairs exhibited a significantly stronger ultimate failure load (median, 196 N; range, 163-212 N) than did the double horizontal mattress suture repairs (median, 106 N; range, 63-229 N) (P = .004). In addition, the 2-tunnel repairs demonstrated decreased gapping at all testing states (P < .05) with a final measured gapping of 1.7 mm and 4.1 mm after 1000 cycles for the 2-tunnel and double horizontal mattress suture repairs, respectively. CONCLUSION: The 2-tunnel repairs displayed significantly less gapping distance after cyclic loading and had significantly stronger ultimate failure loads compared with the double horizontal mattress suture repairs. CLINICAL RELEVANCE: Complete radial tears of the medial meniscus significantly decrease the ability of the meniscus to dissipate tibiofemoral loads, predisposing patients to early osteoarthritis. Improving the ability to repair medial meniscal radial tears in a way that withstands cyclic loads and heals in an anatomic position could significantly improve patient healing rates and result in improved preservation of the articular cartilage of the medial compartment of the knee. The 2-tunnel repair may be a more reliable and stronger repair option for midbody radial tears of the medial meniscus. Clinical studies are warranted to further evaluate these repairs.


Subject(s)
Suture Techniques , Tibial Meniscus Injuries , Adult , Aged , Arthroplasty, Replacement, Knee/methods , Biomechanical Phenomena , Cartilage Diseases/physiopathology , Cartilage Diseases/surgery , Cartilage, Articular/physiology , Cartilage, Articular/surgery , Female , Humans , Knee Injuries/surgery , Knee Joint/surgery , Lacerations/surgery , Male , Menisci, Tibial/physiology , Menisci, Tibial/surgery , Osteoarthritis, Knee/etiology , Rupture/physiopathology , Rupture/surgery , Sutures , Wound Healing/physiology
6.
Am J Sports Med ; 43(8): 1957-64, 2015 Aug.
Article in English | MEDLINE | ID: mdl-26063402

ABSTRACT

BACKGROUND: While the nonoperative management of Achilles tendon ruptures is a viable option, surgical repair is preferred in healthy and active populations. Recently, minimally invasive percutaneous repair methods with assistive devices have been developed. HYPOTHESIS/PURPOSE: The purpose of this study was to biomechanically analyze 3 commercially available, minimally invasive percutaneous techniques compared with an open Achilles repair during a simulated, progressive rehabilitation program. It was hypothesized that no significant biomechanical differences would exist between repair techniques. STUDY DESIGN: Controlled laboratory study. METHODS: A simulated, midsubstance Achilles rupture was created 6 cm proximal to the calcaneal insertion in 33 fresh-frozen cadaveric ankles. Specimens were then randomly allocated to 1 of 4 different Achilles repair techniques: (1) open repair, (2) the Achillon Achilles Tendon Suture System, (3) the PARS Achilles Jig System, or (4) an Achilles Midsubstance SpeedBridge Repair variation. Repairs were subjected to a cyclic loading protocol representative of progressive postoperative rehabilitation: 250 cycles at 1 Hz for each loading range: 20-100 N, 20-200 N, 20-300 N, and 20-400 N. RESULTS: The open repair technique demonstrated significantly less elongation (5.2 ± 1.1 mm) when compared with all minimally invasive percutaneous repair methods after 250 cycles (P < .05). No significant differences were observed after 250 cycles between the Achillon, PARS, or SpeedBridge repairs, with mean displacements of 9.9 ± 2.2 mm, 12.2 ± 4.4 mm, and 10.0 ± 3.9 mm, respectively. When examined over smaller cyclic intervals, the majority of elongation, regardless of repair, occurred within the first 10 cycles. Within the first 10 cycles, open repairs achieved 71.2% of the total elongation observed after 250 cycles. Corresponding values for the Achillon, PARS, and SpeedBridge repairs were 81.8%, 77.9%, and 69.0%, respectively. No significant differences were observed in the total number of cycles to failure between minimally invasive percutaneous repairs and open repairs. Minor differences in the mechanism of failure were noted; however, the majority of all repairs failed at the suture-tendon interface. CONCLUSION: Minimally invasive percutaneous repair techniques demonstrated a susceptibility to significant early repair elongation when compared with open repairs. However, the ultimate strengths of repairs (cycles to failure) were comparable across all techniques. CLINICAL RELEVANCE: The reduced early elongation of open repairs suggests that patients treated with this technique may be able to progress through an earlier and/or more aggressive postoperative rehabilitation protocol with a lower risk of early irrevocable repair elongation or gapping about the repair site. However, in cases where cosmesis or wound-healing complications are of significant concern, minimally invasive percutaneous techniques provide a biomechanically reasonable alternative based on their repair strengths (cycles to failure). These repairs may need to be protected longer postoperatively to allow for biological healing and avoid early repair elongation and potential gapping between the healing tendon ends.


Subject(s)
Achilles Tendon/injuries , Achilles Tendon/surgery , Orthopedic Procedures/methods , Achilles Tendon/physiopathology , Adult , Aged , Biomechanical Phenomena , Cadaver , Female , Humans , Male , Middle Aged , Minimally Invasive Surgical Procedures , Rupture/surgery , Suture Techniques/instrumentation , Sutures , Wound Healing
7.
Am J Sports Med ; 43(12): 3077-92, 2015 Dec.
Article in English | MEDLINE | ID: mdl-25776184

ABSTRACT

The posterior cruciate ligament (PCL) is recognized as an essential stabilizer of the knee. However, the complexity of the ligament has generated controversy about its definitive role and the recommended treatment after injury. A proper understanding of the functional role of the PCL is necessary to minimize residual instability, osteoarthritic progression, and failure of additional concomitant ligament graft reconstructions or meniscal repairs after treatment. Recent anatomic and biomechanical studies have elucidated the surgically relevant quantitative anatomy and confirmed the codominant role of the anterolateral and posteromedial bundles of the PCL. Although nonoperative treatment has historically been the initial treatment of choice for isolated PCL injury, possibly biased by the historically poorer objective outcomes postoperatively compared with anterior cruciate ligament reconstructions, surgical intervention has been increasingly used for isolated and combined PCL injuries. Recent studies have more clearly elucidated the biomechanical and clinical effects after PCL tears and resultant treatments. This article presents a thorough review of updates on the clinically relevant anatomy, epidemiology, biomechanical function, diagnosis, and current treatments for the PCL, with an emphasis on the emerging clinical and biomechanical evidence regarding each of the treatment choices for PCL reconstruction surgery. It is recommended that future outcomes studies use PCL stress radiographs to determine objective outcomes and that evidence level 1 and 2 studies be performed to assess outcomes between transtibial and tibial inlay reconstructions and also between single- and double-bundle PCL reconstructions.


Subject(s)
Knee Injuries/surgery , Posterior Cruciate Ligament/injuries , Posterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Reconstruction , Biomechanical Phenomena , Humans , Joint Instability/surgery , Knee Injuries/diagnosis , Knee Injuries/physiopathology , Knee Joint/anatomy & histology , Knee Joint/physiopathology , Posterior Cruciate Ligament/anatomy & histology , Posterior Cruciate Ligament/physiopathology
8.
Clin J Sport Med ; 24(5): 403-8, 2014 Sep.
Article in English | MEDLINE | ID: mdl-24346735

ABSTRACT

OBJECTIVE: To determine hip kinematics and ground impact forces of the butterfly movement in ice hockey goaltenders for the pre-2005/06 season pads (30.5 cm) versus the current regulation width pads (27.9 cm). DESIGN: Prospective laboratory controlled study. SETTING: Research Institute BioMotion Laboratory. PARTICIPANTS: Ten male ice hockey goaltenders at the Midget AA level or higher. ASSESSMENT OF RISK FACTORS: The participants performed butterfly motions wearing 3 different types of leg pads in a randomized order: own 27.9 cm, standard 27.9 cm, and standard 30.5 cm. In addition, this study investigated hip kinematics and ground impact forces in the pre-2005/06 season pads versus the current regulation width pads. MAIN OUTCOME MEASURES: Kinematics and kinetics were calculated using motion analysis software. RESULTS: The knee ground reaction force upon landing was 1.45 ± 0.43 times the body weight. Hip internal rotation was reduced when goaltenders wore their own, previously "broken-in," set of pads as compared with the set of standard, new 27.9-cm pads (17.5 ± 4.8 vs 20.1 ± 4.8 degrees, respectively; P = 0.032). The recent mandated change in goalie pad from 30.5- to 27.9-cm width had no significant effect on hip kinematics. However, previously worn versus new pads did have an effect on hip kinematics. CONCLUSIONS: The butterfly movement placed ice hockey goaltenders' hips at their passive limits of hip internal rotation and involved knee forces 1.45 times the body weight. The recent mandated change in goalie pad from 30.5- to 27.9-cm width had no significant effect on hip kinematics. However, previously worn versus new pads did have an effect on hip kinematics.


Subject(s)
Hip Joint/physiology , Hockey/physiology , Protective Devices , Range of Motion, Articular/physiology , Adolescent , Biomechanical Phenomena , Humans , Male , Prospective Studies , Young Adult
9.
Am J Sports Med ; 40(10): 2342-7, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22962297

ABSTRACT

BACKGROUND: The clinical importance of the meniscal posterior root attachments has been recently reported by both biomechanical and clinical studies. Although several studies have been performed to evaluate surgical techniques, there have been few studies on the quantitative arthroscopically pertinent anatomy of the posterior meniscal root attachments. HYPOTHESIS: The posterior root attachments of the medial and lateral menisci are consistent among specimens, and repeatable quantitative measurements using arthroscopically pertinent landmarks are achievable. STUDY DESIGN: Descriptive laboratory study. METHODS: Twelve nonpaired, fresh-frozen cadaveric knees were used. The positions of the posterior root attachments of the medial and lateral menisci were identified, and 3-dimensional measurements to arthroscopically pertinent landmarks were performed using a coordinate measuring system. RESULTS: The direct distance (±standard error of the mean) between the medial tibial eminence apex and the medial meniscus posterior root attachment center was 11.5 (±0.9) mm. When split into directional components along the knee's main axes, the medial meniscus posterior root attachment center was 9.6 (±0.8) mm posterior and 0.7 (±0.4) mm lateral along the bony surface from the medial tibial eminence apex. It was located 3.5 (±0.4) mm lateral from the medial articular cartilage inflection point and directly 8.2 (±0.7) mm from the nearest tibial attachment margin of the posterior cruciate ligament. The direct distance between the lateral tibial eminence apex and the lateral meniscus posterior root attachment center was 5.3 (±0.3) mm. When it was split into directional components using the knee's main axes, the lateral meniscus posterior root attachment center was 4.2 (±0.4) mm medial and 1.5 (±0.7) mm posterior from the lateral tibial eminence apex. The lateral meniscus posterior root attachment center was located 4.3 (±0.5) mm medial from the nearest articular cartilage margin and directly 12.7 (±1.1) mm from the nearest margin of the tibial attachment of the posterior cruciate ligament. CONCLUSION: This quantitative study reproducibly identified the posterior root attachment centers of the medial and lateral menisci in relation to arthroscopically pertinent landmarks and guidelines. CLINICAL RELEVANCE: These data can be directly applied to assist in anatomic meniscal root repairs.


Subject(s)
Knee Joint/anatomy & histology , Menisci, Tibial/anatomy & histology , Adult , Arthroscopy , Cadaver , Female , Humans , Knee Joint/surgery , Male , Menisci, Tibial/surgery , Middle Aged , Young Adult
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