Subject(s)
Abscess/microbiology , Breast Diseases/microbiology , Leuconostoc/isolation & purification , Abscess/drug therapy , Adolescent , Breast Diseases/drug therapy , Drug Resistance, Microbial , Escherichia coli/isolation & purification , Female , Humans , Penicillins/therapeutic use , Streptococcus/isolation & purificationABSTRACT
An outbreak of gentamicin- and tobramycin-resistant Pseudomonas aeruginosa infection occurred in a surgical ward over a three-month period. Resistant Ps. aeruginosa strains with the same serological, phage, and pyocin type were cultured from the urine of six patients. Identical organisms were found on urine bottles, bedpans, and the hands of attendant staff. Inadequate disinfection played a major role in cross-infection. Isolates of the epidemic strain from each of the patients and of an unrelated but similarly resistant Ps. aeruginosa from one of them could transfer resistance to a recipient strain of Ps. aeruginosa. Resistance to gentamicin, kanamycin, tobramycin, sulphonamides, and mercuric chloride was determined by R factors belonging to Pseudomonas incompatibility group P-3. Aminoglycoside resistance was due to acetylation.
Subject(s)
Anti-Bacterial Agents/pharmacology , Cross Infection/microbiology , Gentamicins/pharmacology , Hospital Departments , Hospital Units , Pseudomonas Infections/microbiology , Pseudomonas aeruginosa/drug effects , Surgery Department, Hospital , Tobramycin/pharmacology , Aged , Bacteriuria/microbiology , Drug Resistance, Microbial , Female , Humans , Ireland , Male , Middle Aged , Pseudomonas aeruginosa/genetics , R FactorsABSTRACT
Opportunistic fungal infection is recognised as a complication of intravenous therapy (Zinneret al., 1969), prolonged antibiotic usage, immuno-suppressives, steroids, radiotherapy and in patients whose host defences are impaired (Klainer and Beisel, 1969). We describe here a patient with Hodgkin's disease who developed disseminated candidiasis associated with an indwelling venous catheter.
ABSTRACT
A case of Clostridium welchii septicaemia following acute cholecystitis is described. The onset was acute and a rapidly fatal outcome ensued. Radiological findings were negative. An approach to the antibiotic treatment and general management is discussed.
