ABSTRACT
De 35 pacientes com pielonefrite aguda, inicialmente triados para participarem do estudo, 28 receberam tratamento com 400 mg de pefloxacina, uma quinolona fluorada, duas vezes ao dia, por um período de 10 dias. Todos os pacientes foram acompanhados, clínica e laboratorialmente, por cerca de 40 dias. O índice de sucesso, ou seja, cura clínica e laboratorial, foi de 96,3 por cento. Três pacientes (10,7 por cento) apresentaram reaçao adversa, caracterizada por intolerância gástrica. Em apenas um paciente foi necessária a suspensao da antibioticoterapia
Subject(s)
Humans , Female , Male , Acute Disease , Pefloxacin/therapeutic use , Pyelonephritis/drug therapyABSTRACT
Transurethral microwave thermotherapy was administered to 91 consecutive men with moderate to severe benign prostatic hyperplasia. Mean patient age was 68 years, with a range of 55 to 87 years. Treatment was given in one 60-minute session, on an outpatient basis and without anesthesia. Of the 91 original patients 67 (73.6%) were followed from 3 to 18 months, mean 6.1 months. The microwave emission was continuously monitored to permit the control of the urethral temperature level. Patients were prospective and randomly assessed into 2 groups: group 1 (34 patients) who underwent treatment with urethral temperature between 42 and 43 degrees C and group 2 (33 patients) treated with higher temperature ranging between 43.1 and 45 degrees C. There was improvement of the irritative and obstructive symptoms, prostate weight and residual urine, in both groups after treatment (p < 0.001). PSA did not show a statistically significant difference after TUMT in both groups. Uroflow improved in both groups after the treatment; however, only the group treated with higher temperature showed statistically significant difference (p < 0.001). In the lower temperature group there were 2/34 (5.8%) failures; both patients were still obstructed and underwent transurethral resection. A total of 2/33 (6%) failures were observed in the higher temperature group. Patients showed no general conditions which might allow the use of anesthesia. Therefore, they underwent a second postoperative microwave treatment after 2 and 3 months with uneventful clinical recovery at an early follow-up. No systemic complications were encountered. There were minor complications such as epididymitis, urethral bleeding and severe micturition discomfort within the first 30 days postoperative.(ABSTRACT TRUNCATED AT 250 WORDS)
Subject(s)
Hyperthermia, Induced , Microwaves/therapeutic use , Prostatic Hyperplasia/therapy , Aged , Aged, 80 and over , Ambulatory Care , Body Temperature , Follow-Up Studies , Humans , Hyperthermia, Induced/adverse effects , Hyperthermia, Induced/methods , Male , Microwaves/adverse effects , Middle Aged , Monitoring, Physiologic , Prospective Studies , Prostatic Hyperplasia/physiopathology , Time Factors , Treatment Failure , Treatment Outcome , Urethra/physiopathology , Urination/physiologyABSTRACT
The records of 325 azoospermic patients were reviewed. A total of 109 patients (33.5%) had obstructive azoospermia and 48 of them underwent surgical treatment. Three patients had vas deferens agenesia and underwent artificial spermatocele; 14 with epididymal obstruction were treated by an end-to-end microsurgical vasoepididymostomy; and 31 vasectomized patients were submitted to microsurgical reversal. There was no pregnancy in the spermatocele patients. In the vasoepididymostomy patients 60% became patent and 30% achieved pregnancy. In the reversal group 90% of patency and pregnancy rate of 80% were observed, in a mean follow-up of 21 months. The last 8 cases were treated with a biological glue and 7 showed patency and one pregnancy in a 3-month follow-up period. One was lost to follow-up.
Subject(s)
Oligospermia/surgery , Adult , Aged , Follow-Up Studies , Genital Diseases, Male/complications , Humans , Male , Middle Aged , Oligospermia/etiologyABSTRACT
A total of 71 patients with superficial transitional cell carcinoma underwent transurethral resection of bladder tumor. All patients had stage pTa or pT1 transitional cell carcinoma or carcinoma in situ without other concurrent malignancies. The patients were assigned to 3 treatment groups: control group--transurethral resection discontinued within the study, oral bacillus Calmette-Guerin (BCG) group--transurethral resection of bladder tumor plus BCG (Moreau) and intravesical BCG group--transurethral resection of bladder tumor plus BCG. Of 9 patients in the control group 8 (89%) experienced tumor recurrence during a mean followup of 20 months. Of the 28 patients in the oral BCG group 11 (39.3%) had recurrence during a mean followup of 36 months. Of the 34 patients in the intravesical group 6 (18%) had recurrence in a 24-month mean followup. The incidence of complications was higher in the intravesical (41.2%) than in the oral BCG group (28.5%). These results show that intravesical BCG is a more effective immunotherapy; however, oral BCG can be used in patients who do not accept intravesical BCG administration.
