ABSTRACT
We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.
Subject(s)
Anti-Bacterial Agents/pharmacology , Enterococcus faecium/genetics , Enterococcus faecium/isolation & purification , Gram-Positive Bacterial Infections/microbiology , Vancomycin-Resistant Enterococci/genetics , Vancomycin-Resistant Enterococci/isolation & purification , Vancomycin/pharmacology , Bacterial Proteins/genetics , Carbon-Oxygen Ligases , DNA, Bacterial/genetics , Denmark/epidemiology , Electrophoresis, Gel, Pulsed-Field , Enterococcus faecium/drug effects , Gram-Positive Bacterial Infections/epidemiology , Humans , Microbial Sensitivity Tests , Multilocus Sequence Typing , Polymerase Chain Reaction , Prevalence , Sentinel Surveillance , Sequence Analysis, DNA , Vancomycin-Resistant Enterococci/drug effectsABSTRACT
A 27-year-old female patient with no previous medical history, presented a computed tomography displaying a calcified retroperitoneal cyst. The patient had experienced occasional abdominal pain in her right side. The tumour was found in the retroperitoneum, was non-adherent to neighbouring organs and was excised laparoscopically without postoperative complications. Histology revealed a benign, cystic mass, with calcification and osseous metaplasia in the cyst wall, and no epithelia. The material of the cyst was amorphic and necrotic. No other retroperitoneal masses alike has been described in the literature.
