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Oncol Res Treat ; 2024 Jun 13.
Article in English | MEDLINE | ID: mdl-38870920

ABSTRACT

INTRODUCTION: Stomach cancer is one of the most common causes of cancer worldwide, especially in the population over 65 years, the survival rate is less in comparison with young people, the evaluation of geriatric assessment would be key for assessing the prognosis of these patients. METHODS: A search was performed in the OVID, EMBASE and PUBMED databases, and after applying inclusion and exclusion criteria, four (4) articles were analyzed. RESULTS: In the included studies, the MGA battery was not implemented, but rather easily measurable scales as nutritional status, functional status, cognitive and behavioral disorders, comorbidities, and polypharmacy, some authors proposed through the assessment of overall survival is not explicit among the included studies, patients with gastric cancer and mild, moderate, severe, and total dependence had a higher mortality than independent patients (39% HR 1.39; 95% CI 1.09-1.7), 68% (95% CI: 1.46-1.93), 187% (HR 2.87 95% CI: 2.47-3.34), and 234% 95% CI: 2.81-3.97), respectively. The Zhou study showed an association between sarcopenia, assessed by imaging studies, and a longer hospital stay in days (16 [9] vs. 13 [6], p 0.004). The study by Pujara found that polypharmacy (OR 2.36 CI 1.08-5.17) and weight loss greater than 10% in the past 6 months were associated with greater postoperative morbidity at 90 days (OR 2.36 CI 1.08-5.17, (OR 11.21 IC 2.16-58.24). CONCLUSION: Geriatric assessment dependency appear to be prognostic markers of survival in patients with gastric cancer, however, higher quality studies in this specific population are required to support the systematic use of this assessment for the choice of appropriate therapy according to the patient.

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