Neurobiological mechanisms supporting experience-dependent resistance to social stress.

Humans and other animals show a remarkable capacity for resilience following traumatic, stressful events. Resilience is thought to be an active process related to coping with stress, although the cellular and molecular mechanisms that support active coping and stress resistance remain poorly understood. In this review, we focus on the neurobiological mechanisms by which environmental and social experiences promote stress resistance. In male Syrian hamsters, exposure to a brief social defeat stressor leads to increased avoidance of novel opponents, which we call conditioned defeat. Also, hamsters that have achieved dominant social status show reduced conditioned defeat as well as cellular and molecular changes in the neural circuits controlling the conditioned defeat response. We propose that experience-dependent neural plasticity occurs in the prelimbic (PL) cortex, infralimbic (IL) cortex, and ventral medial amygdala (vMeA) during the maintenance of dominance relationships, and that adaptations in these neural circuits support stress resistance in dominant individuals. Overall, behavioral treatments that promote success in competitive interactions may represent valuable interventions for instilling resilience.

Optical properties of synthetic carbon nanoparticles as model of cosmic dust.

Carbon nanoparticles synthesised by laser pyrolysis of small hydrocarbons are deposited at low energy on a silicon substrate. Infrared spectroscopy of the as-formed films are studied as a function of the synthesis parameters and post-treatments, such as annealing and heavy ion irradiation. Correlation between infrared spectroscopy and multiscale organisation of the samples is made through transmission electron microscopy, including image analysis. Changes in infrared spectra are analysed in terms of the carbon network building. The relevance of the results to model the structure and spectroscopy of carbon dust in the carbon-rich circumstellar media is discussed.