ABSTRACT
Respiratory syncytial virus (RSV) is the most important cause of acute viral bronchiolitis and pneumonia in infants and children. Management of RSV infection has changed dramatically over the past 5 to 7 years because of (1) the advent of widely available rapid tests for its specific identification and (2) use of the antiviral agent ribavirin (Virazole). Although RSV infection remains a life-threatening disease, particularly in certain high-risk groups, appropriate management and judicious use of ribavirin should help physicians reduce its morbidity and mortality.
Subject(s)
Respiratory Syncytial Viruses , Respirovirus Infections , Aerosols , Ambulatory Care , Antiviral Agents/administration & dosage , Bronchiolitis, Viral/diagnosis , Bronchiolitis, Viral/therapy , Cross Infection/prevention & control , Hospitalization , Humans , Infant , Respirovirus Infections/diagnosis , Respirovirus Infections/therapy , Respirovirus Infections/transmission , Risk FactorsABSTRACT
Benign osteoblastoma is a rare lesion of bone, usually confined to the long bones and the vertebrae. There have been 16 cases reported in the calvarium and only four in the frontal bone. We treated a patient with benign osteoblastoma of the frontal bone (supraorbital ridge and roof of orbit), and we review the literature. The histologic and radiologic characteristics are described and the treatment modalities are reviewed.
Subject(s)
Frontal Bone , Osteoma, Osteoid/diagnostic imaging , Skull Neoplasms/diagnostic imaging , Adolescent , Curettage , Humans , Male , Orbit , Osteoma, Osteoid/pathology , Osteoma, Osteoid/surgery , Skull Neoplasms/pathology , Skull Neoplasms/surgery , Tomography, X-Ray ComputedABSTRACT
Fifty eight patients receiving planned high-dose preoperative radiotherapy followed by en bloc oro-mandibular-cervical resection for oropharyngeal cancer were reviewed. These patients received continued close observation and care from both the Otolaryngology and Radiotherapy services. In light of the ongoing controversy of preoperative vs. postoperative radiotherapy, we present our data demonstrating the value of preoperative radiation. An overall tumor control rate of 66% was achieved, with an adjusted survival rate of 62%. This was not only for early lesions, but also in patients having advanced (T3, T4) tumor and/or nodal disease (N1-4). These figures are somewhat higher than expected from the literature. A review and discussion of the surgical complications are also presented.
