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1.
Actas urol. esp ; 45(10): 642-647, diciembre 2021. tab
Article in Spanish | IBECS | ID: ibc-217141

ABSTRACT

Introducción: La tasa de complicaciones a largo plazo tras la reparación del hipospadias distal puede ascender al 20%, y aún no disponemos de directrices sobre la colocación de la sonda en la uretroplastia distal. Hemos analizado de forma retrospectiva la tasa de reintervención de la uretroplastia a medio plazo y los resultados estéticos tras un estudio piloto de 2años sobre las uretroplastias distales con colocación de sonda o sin ella.Materiales y métodosUn cirujano pediátrico realizó 11 procedimientos con la técnica de Snodgrass con colocación de sonda (grupo A) y 17 sin colocación de sonda (grupo B) en nuestra institución (2011-2013). La mediana de edad de los pacientes en la cirugía fue de 2,1 años (rango 1-8,5).Los criterios de inclusión fueron: defecto distal primitivo, un único cirujano en ambos procedimientos y alta sin sonda.La mediana de seguimiento fue de 6,4 años (rango 1,5-8,1).Los resultados clínicos y estéticos postoperatorios fueron evaluados al menos una vez mediante la herramienta HOSE (Hypospadias Objective Scoring Evaluation).El objetivo de nuestro estudio fue comparar las complicaciones y las tasas de repetición de la uretroplastia a medio plazo antes de iniciar un estudio aleatorizado. Se hizo un análisis retrospectivo. Se utilizó la prueba exacta de Fisher (p <0,05) para el análisis estadístico.ResultadosDe los 28 del total, 5 complicaciones requirieron una segunda cirugía: 2/11 casos con sonda, 3/17 sin sonda. Los resultados estéticos fueron satisfactorios en ambos grupos. Los resultados no alcanzaron significación estadística (p=1.000). (AU)


Introduction: Long-term complication rates after distal hypospadias repair can be close to 20%. There are no available guidelines regarding the need of a catheter in distal urethroplasty. We report a retrospective analysis on medium-term redo-urethroplasty rate and cosmetic results after a two-year pilot study on stented/un-stented distal urethroplasties.Materials and methodsA total of 11 stented (Group A) and 17 un-stented (Group B) Snodgrass-procedures were performed by one pediatric surgeon at our Institution (2011-2013). The median age at surgery was 2.1 years (range 1-8.5).Inclusion criteria were primitive distal defect, same surgeon in both interventions, catheter-free discharge.The median follow-up was 6.4 years (range 1.5-8.1).All patients received at least one post-operative clinical-cosmetic examination (HOSE).The aim of our study was to compare medium-term complications and redo-urethroplasty rates before starting a randomized study. A retrospective analysis was performed. We used Fisher's exact-test (P<0.05) for statistical analysis.ResultsOf 28 complications, 5 required redo-surgery: 2/11 stented-cases, 3/17 un-stented. Cosmetic results were satisfactory in both groups. These results were not statistically significant (P=1.000). (AU)


Subject(s)
Humans , Hypospadias , Treatment Outcome , Urologic Surgical Procedures , Retrospective Studies
2.
Actas Urol Esp (Engl Ed) ; 45(10): 642-647, 2021 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-34764052

ABSTRACT

INTRODUCTION: Long-term complication rates after distal hypospadias repair can be close to 20%. There are no available guidelines regarding the need for a catheter in distal urethroplasty. We report a retrospective analysis on medium-term redo-urethroplasty rate and cosmetic results after a two-years pilot study on stented/un-stented distal urethroplasties. MATERIALS AND METHODS: A total of 11 stented (Group A) and 17 un-stented (Group B) Snodgrass-procedures were performed by the same pediatric surgeon at our Institution (2011-2013). The median age at surgery was 2.1 years (range 1-8.5). Inclusion criteria were primitive distal defect, same surgeon in both interventions, catheter-free discharge. The median follow-up was 6.4 years (range 1.5-8.1). All patients received at least one post-operative clinical-cosmetic examination (HOSE). The aim of our study was to compare medium-term complications and redo-urethroplasty rates before starting a randomized study. A retrospective analysis was performed. We used Fisher's exact-test (P < 0.05) for statistical analysis. RESULTS: Of 28 complications, 5 required redo-surgery: 2/11 stented-cases, 3/17 un-stented. Cosmetic results were satisfactory in both groups. These results were not statistically significant (P = 1.000). CONCLUSION: Long-term follow-up is mandatory to know redo-urethroplasty rate and cosmetic outcome after distal stented/un-stented repair. Further studies are needed to evaluate the role of catheter placement and the definitive outcome in distal urethroplasty.


Subject(s)
Hypospadias , Urologic Surgical Procedures, Male , Child , Child, Preschool , Humans , Hypospadias/surgery , Infant , Male , Pilot Projects , Retrospective Studies , Treatment Outcome
3.
Article in English, Spanish | MEDLINE | ID: mdl-34332810

ABSTRACT

INTRODUCTION: Long-term complication rates after distal hypospadias repair can be close to 20%. There are no available guidelines regarding the need of a catheter in distal urethroplasty. We report a retrospective analysis on medium-term redo-urethroplasty rate and cosmetic results after a two-year pilot study on stented/un-stented distal urethroplasties. MATERIALS AND METHODS: A total of 11 stented (Group A) and 17 un-stented (Group B) Snodgrass-procedures were performed by one pediatric surgeon at our Institution (2011-2013). The median age at surgery was 2.1 years (range 1-8.5). Inclusion criteria were primitive distal defect, same surgeon in both interventions, catheter-free discharge. The median follow-up was 6.4 years (range 1.5-8.1). All patients received at least one post-operative clinical-cosmetic examination (HOSE). The aim of our study was to compare medium-term complications and redo-urethroplasty rates before starting a randomized study. A retrospective analysis was performed. We used Fisher's exact-test (P<0.05) for statistical analysis. RESULTS: Of 28 complications, 5 required redo-surgery: 2/11 stented-cases, 3/17 un-stented. Cosmetic results were satisfactory in both groups. These results were not statistically significant (P=1.000). CONCLUSION: Long-term follow-up is mandatory to know redo-urethroplasty rate and cosmetic outcome after distal stented/un-stented repair. Further studies are needed to evaluate the role of catheter placement and the definitive outcome in distal urethroplasty.

4.
J Pediatr Surg ; 50(9): 1441-56, 2015 Sep.
Article in English | MEDLINE | ID: mdl-25783403

ABSTRACT

BACKGROUND: Our study aims at disclosing epidemiology and most relevant clinical features of esophageal atresia (EA) pointing to a model of multicentre collaboration. METHODS: A detailed questionnaire was sent to all Italian Units of pediatric surgery in order to collect data of patients born with EA between January and December 2012. The results were crosschecked by matching date and place of birth of the patients with those of diagnosis-related group provided by the Italian Ministry of Health (MOH). RESULTS: A total of 146 questionnaires were returned plus a further 32 patients reported in the MOH database. Basing on a total of 178 patients with EA born in Italy in 2012, the incidence of EA was calculated in 3.33 per 10,000 live births. Antenatal diagnosis was suspected in 29.5% patients. 55.5% showed associated anomalies. The most common type of EA was Gross type C (89%). Postoperative complications occurred in 37% of type C EA and 100% of type A EA. A 9.5% mortality rate was reported. CONCLUSIONS: This is the first Italian cross-sectional nationwide survey on EA. We can now develop shared guidelines and provide more reliable prognostic expectations for our patients.


Subject(s)
Esophageal Atresia/epidemiology , Prenatal Diagnosis , Surveys and Questionnaires , Tracheoesophageal Fistula/epidemiology , Adult , Cross-Sectional Studies , Diagnosis-Related Groups , Esophageal Atresia/diagnosis , Female , Humans , Incidence , Infant, Newborn , Italy/epidemiology , Male , Pregnancy , Tracheoesophageal Fistula/diagnosis , Young Adult
5.
Hernia ; 18(3): 417-21, 2014 Jun.
Article in English | MEDLINE | ID: mdl-23324869

ABSTRACT

Hepatic pulmonary fusion is a rare malformation associated with right congenital diaphragmatic hernia (CDH), often only discovered during surgical repair of the defect. Fourteen previous cases have been reported in the literature. We describe a case of a full term male newborn with prenatal ultrasound diagnosis of right CDH who underwent a thoracoscopy converted to a thoracotomy, due to this rare aforementioned intraoperative incidental finding. We reviewed the previous reported literature, especially focusing on the chosen surgical approach, concluding that an early and appropriate preoperative imaging investigation may be crucial for the best management of these kinds of patients.


Subject(s)
Digestive System Abnormalities/diagnosis , Hernias, Diaphragmatic, Congenital/surgery , Liver/abnormalities , Lung/abnormalities , Respiratory System Abnormalities/diagnosis , Hernias, Diaphragmatic, Congenital/complications , Humans , Incidental Findings , Infant, Newborn , Male
6.
Minim Invasive Surg ; 2013: 216416, 2013.
Article in English | MEDLINE | ID: mdl-23606960

ABSTRACT

The paper reports the results of a retrospective review of the medical charts of 203 patients admitted to a pediatric surgical unit with a diagnosis of acute appendicitis between January 2006 and December 2010 when a transumbilical laparoscopic-assisted appendectomy (TULAA) was introduced as a new surgical technique. Among 203 admitted patients, 7 (3.5%) had a localized appendiceal abscess and were treated with antibiotics. All of them responded to antibiotics and underwent TULAA interval appendectomy 8 weeks later. 196 patients (96.5%) underwent immediate surgery. In 12/181 (6.6%) urgent cases, conversion to laparotomy was necessary, in 3 patients because of bowel distension and in 9 for retrocecal position of appendix. In all 181 TULAA completed procedures, one trocar was used in 151 cases (89.4%), two trocars in 16 (9.4%), and three trocars in 2 (1.2%). The mean operative time for single port TULAA was 52' Complications included 5 wound infections and 5 intra-abdominal abscesses, all managed conservatively. In conclusion, TULAA is a safe, minimally invasive approach with acute appendicitis, regardless of the perforation status, and can be recommended in the pediatric urgical settings.

7.
Curr Med Chem ; 20(17): 2176-87, 2013.
Article in English | MEDLINE | ID: mdl-23458614

ABSTRACT

This review focuses on the use of Raman spectroscopy, an analytical technique based on the inelastic scattering of harmless laser light with biological tissues, as an innovative diagnostic tool in pediatrics. After a brief introduction to explain the fundamental concepts behind Raman spectroscopy and imaging, a short summary is given of the most important and common issues arising when handling spectral data with multivariate statistics. Then, the most relevant papers in which Raman spectroscopy or imaging has been applied with diagnostic purposes to pediatric patients are reviewed, and grouped according to the type of pathology: neoplastic, inflammatory, allergic, malformative as well as other kinds. Raman spectroscopy has been used both in vivo, mostly using optical fibers for tissue illumination, as well as on ex vivo tissue sections in a microscopic imaging approach defined as "spectral histopathology". According to the results reported so far, this technique showed a huge potential for mini- or non-invasive real-time, bedside and intra-operatory diagnosis, as well as for an ex vivo imaging tool in support to pathologists. Despite many studies are limited by the small sample size, this technique is extremely promising in terms of sensitivity and specificity.


Subject(s)
Neoplasms/diagnosis , Spectrum Analysis, Raman , Barrett Esophagus/pathology , Brain Neoplasms/pathology , Child , Cluster Analysis , Dermatitis, Atopic/pathology , Humans , Inflammatory Bowel Diseases/pathology , Models, Statistical , Neoplasms/pathology , Principal Component Analysis
8.
Pediatr Surg Int ; 17(7): 521-3, 2001 Sep.
Article in English | MEDLINE | ID: mdl-11666049

ABSTRACT

Internal anal sphincter (IAS) achalasia is a disorder of defecation in which the IAS fails to relax. Botulinum toxin (BT), which has been successfully used to relax the anal and lower esophageal sphincters, was injected twice into the IAS of one adolescent and three infants with manometric, radiologic, and in 2 cases histochemical diagnosis of anal achalasia: in the adolescent a third injection was necessary. Spontaneous defecation was achieved in all patients following the second injection. In one case a diagnosis of short-segment Hirschsprung's disease was obtained after the second injection. Local infiltration of BT into the IAS proved effective in the treatment of IAS achalasia. Double-blind studies and longer follow-up periods are needed to better evaluate these preliminary results and define the limits of this promising therapy.


Subject(s)
Botulinum Toxins, Type A/therapeutic use , Defecation , Neuromuscular Agents/therapeutic use , Rectal Diseases/drug therapy , Botulinum Toxins, Type A/pharmacology , Child , Constipation/drug therapy , Female , Humans , Infant, Newborn , Male , Muscle, Smooth/drug effects , Neuromuscular Agents/pharmacology , Pilot Projects
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